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1995 5
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2002 6
2003 8
2004 11
2005 7
2006 15
2007 16
2008 20
2009 27
2010 24
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664 results

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Page 1
Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis.
Yu W, Xie Z, Li J, Lin J, Su Z, Che Y, Ye F, Zhang Z, Xu P, Zeng Y, Xu X, Li Z, Feng P, Mi R, Wu Y, Shen H. Yu W, et al. Bone Res. 2023 Jun 7;11(1):30. doi: 10.1038/s41413-023-00267-8. Bone Res. 2023. PMID: 37280207 Free PMC article.
Through integrated analysis, we identified the most common SE-targeted and osteoporosis-related osteogenic gene, ZBTB16. ZBTB16, positively regulated by SEs, promoted MSC osteogenesis but was expressed at lower levels in osteoporosis. ...During osteogenesis, histone …
Through integrated analysis, we identified the most common SE-targeted and osteoporosis-related osteogenic gene, ZBTB16. ZBTB16 …
ZBTB16 and metabolic syndrome: a network perspective.
Šeda O, Šedová L, Včelák J, Vaňková M, Liška F, Bendlová B. Šeda O, et al. Physiol Res. 2017 Sep 26;66(Suppl 3):S357-S365. doi: 10.33549/physiolres.933730. Physiol Res. 2017. PMID: 28948820 Free article. Review.
Based on current evidence, we provide a network view of relations between ZBTB16 and hallmarks of metabolic syndrome in order to elucidate the potential functional links involving the ZBTB16 node. ...In summary, ZBTB16 represents a promising pleiotropic candi …
Based on current evidence, we provide a network view of relations between ZBTB16 and hallmarks of metabolic syndrome in order to eluc …
Enhanced ZBTB16 Levels by Progestin-Only Contraceptives Induces Decidualization and Inflammation.
Arlier S, Kayisli UA, Semerci N, Ozmen A, Larsen K, Schatz F, Lockwood CJ, Guzeloglu-Kayisli O. Arlier S, et al. Int J Mol Sci. 2023 Jun 23;24(13):10532. doi: 10.3390/ijms241310532. Int J Mol Sci. 2023. PMID: 37445713 Free PMC article.
ZBTB16 was overexpressed in cultured HESCs for 72 h followed by a 1 IU/mL thrombin treatment for 6 h. ...The in vitro findings indicated that: (1) ZBTB16 levels were significantly elevated by all progestin treatments; (2) MPA exerted the greatest effect on ZBTB16 …
ZBTB16 was overexpressed in cultured HESCs for 72 h followed by a 1 IU/mL thrombin treatment for 6 h. ...The in vitro findings indica …
Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC.
Dong D, Du Y, Fei X, Yang H, Li X, Yang X, Ma J, Huang S, Ma Z, Zheng J, Chan DW, Shi L, Li Y, Irving AT, Yuan X, Liu X, Ni P, Hu Y, Meng G, Peng Y, Sadler A, Xu D. Dong D, et al. Nat Commun. 2023 Dec 20;14(1):8465. doi: 10.1038/s41467-023-43945-1. Nat Commun. 2023. PMID: 38123560 Free PMC article.
We show that the function of ASC in assembling the inflammasome is controlled by its modification with SUMO (small ubiquitin-like modifier) and identify that the nuclear ZBTB16 (zinc-finger and BTB domain-containing protein 16) promotes this SUMOylation. The physiological …
We show that the function of ASC in assembling the inflammasome is controlled by its modification with SUMO (small ubiquitin-like modifier) …
Zbtb16 regulates social cognitive behaviors and neocortical development.
Usui N, Berto S, Konishi A, Kondo M, Konopka G, Matsuzaki H, Shimada S. Usui N, et al. Transl Psychiatry. 2021 Apr 24;11(1):242. doi: 10.1038/s41398-021-01358-y. Transl Psychiatry. 2021. PMID: 33895774 Free PMC article.
Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor cell proliferation and neuronal differentiation during development, however, how the function of ZBTB16 is involved in brain function and behaviors unknown. ...Co-expression ne …
Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor cell proliferation and neuronal differentia …
Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia.
Fabiani E, Cicconi L, Nardozza AM, Cristiano A, Rossi M, Ottone T, Falconi G, Divona M, Testi AM, Annibali O, Castelli R, Lazarevic V, Rego E, Montesinos P, Esteve J, Venditti A, Della Porta M, Arcese W, Lo-Coco F, Voso MT. Fabiani E, et al. Cancer Med. 2021 Jun;10(12):3839-3847. doi: 10.1002/cam4.3904. Epub 2021 May 27. Cancer Med. 2021. PMID: 34042280 Free PMC article.
BACKGROUND: The ZBTB16-RARA fusion gene, resulting from the reciprocal translocation between ZBTB16 on chromosome 11 and RARA genes on chromosome 17 [t(11;17)(q23;q21)], is rarely observed in acute myeloid leukemia (AML), and accounts for about 1% of retinoic acid r …
BACKGROUND: The ZBTB16-RARA fusion gene, resulting from the reciprocal translocation between ZBTB16 on chromosome 11 and RARA …
ZBTB16 eases lipopolysaccharide-elicited inflammation, apoptosis and degradation of extracellular matrix in chondrocytes during osteoarthritis by suppressing GRK2 transcription.
Xiong B, Chen L, Huang Y, Lu G, Chen C, Nong J, Pan H. Xiong B, et al. Exp Ther Med. 2023 Apr 24;25(6):276. doi: 10.3892/etm.2023.11975. eCollection 2023 Jun. Exp Ther Med. 2023. PMID: 37206562 Free PMC article.
The present study was designed to elaborate the potential impact of ZBTB16 on OA and to possibly assess any latent regulatory mechanism. ...Chromatin immunoprecipitation and luciferase reporter assays were then used to determine the potential interaction between ZBTB16 …
The present study was designed to elaborate the potential impact of ZBTB16 on OA and to possibly assess any latent regulatory mechani …
ZBTB16: A new biomarker for primitive neuroectodermal tumor element / Ewing sarcoma.
Xiao GQ, Sherrod AE, Hurth KM. Xiao GQ, et al. Pathol Res Pract. 2019 Oct;215(10):152536. doi: 10.1016/j.prp.2019.152536. Epub 2019 Jul 13. Pathol Res Pract. 2019. PMID: 31326195
Of note, compared to the expression of ZBTB16 in pPNET/Ewing sarcoma and gPNET, the expression of ZBTB16 in cPNET was more variable, which appears consistent with the heterogeneity of cPNET. The close proximity of ZBTB16 and FLI-1 genes on chromosome 11q may …
Of note, compared to the expression of ZBTB16 in pPNET/Ewing sarcoma and gPNET, the expression of ZBTB16 in cPNET was more var …
ZBTB16-RARalpha-Positive Atypical Promyelocytic Leukemia: A Case Report.
Pardo Gambarte L, Franganillo Suárez A, Cornago Navascués J, Soto de Ozaeta C, Blas López C, Atance Pasarisas M, Salgado Sánchez RN, Serrano Del Castillo C, Mata Serna R, Velasco Rodríguez D, López-Lorenzo JL, Llamas-Sillero P, Solán Blanco L. Pardo Gambarte L, et al. Medicina (Kaunas). 2022 Apr 6;58(4):520. doi: 10.3390/medicina58040520. Medicina (Kaunas). 2022. PMID: 35454359 Free PMC article.
CASE SUMMARY: We describe the case of variant APL with the ZBTB16-RARA fusion gene, showing a distinct morphology of classical APL, characterized by crystalline intracytoplasmic inclusions in both peripheral blood (PB) and bone marrow (BM) patients' blasts. ...This observa …
CASE SUMMARY: We describe the case of variant APL with the ZBTB16-RARA fusion gene, showing a distinct morphology of classical APL, c …
Zbtb16 mediates a switch between Fgf signalling regimes in the developing hindbrain.
Leino SA, Constable SCJ, Streit A, Wilkinson DG. Leino SA, et al. Development. 2023 Sep 15;150(18):dev201319. doi: 10.1242/dev.201319. Epub 2023 Sep 14. Development. 2023. PMID: 37642135 Free PMC article.
Zbtb16 expression is high in the early anterior hindbrain, then gradually upregulated posteriorly and confined to neural progenitors. In mutants lacking functional Zbtb16, fgf3 expression fails to be downregulated and persists until a late stage, resulting in excess …
Zbtb16 expression is high in the early anterior hindbrain, then gradually upregulated posteriorly and confined to neural progenitors. …
664 results