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Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer's disease.
Hartlage-Rübsamen M, Ratz V, Zeitschel U, Finzel L, Machner L, Köppen J, Schulze A, Demuth HU, von Hörsten S, Höfling C, Roßner S. Hartlage-Rübsamen M, et al. Among authors: zeitschel u. Acta Neuropathol Commun. 2019 May 20;7(1):79. doi: 10.1186/s40478-019-0726-2. Acta Neuropathol Commun. 2019. PMID: 31109380 Free PMC article.
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.
Hartlage-Rübsamen M, Morawski M, Waniek A, Jäger C, Zeitschel U, Koch B, Cynis H, Schilling S, Schliebs R, Demuth HU, Rossner S. Hartlage-Rübsamen M, et al. Among authors: zeitschel u. Acta Neuropathol. 2011 Jun;121(6):705-19. doi: 10.1007/s00401-011-0806-2. Epub 2011 Feb 8. Acta Neuropathol. 2011. PMID: 21301857 Free PMC article.
Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Höfling C, Morawski M, Zeitschel U, Zanier ER, Moschke K, Serdaroglu A, Canneva F, von Hörsten S, De Simoni MG, Forloni G, Jäger C, Kremmer E, Roßner S, Lichtenthaler SF, Kuhn PH. Höfling C, et al. Among authors: zeitschel u. Aging Cell. 2016 Oct;15(5):953-63. doi: 10.1111/acel.12508. Epub 2016 Jul 29. Aging Cell. 2016. PMID: 27470171 Free PMC article.
The transcription factor Yin Yang 1 is an activator of BACE1 expression.
Nowak K, Lange-Dohna C, Zeitschel U, Günther A, Lüscher B, Robitzki A, Perez-Polo R, Rossner S. Nowak K, et al. Among authors: zeitschel u. J Neurochem. 2006 Mar;96(6):1696-707. doi: 10.1111/j.1471-4159.2006.03692.x. J Neurochem. 2006. PMID: 16539685 Free article.
29 results