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ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export.
Malla S, Prasad Bhattarai D, Groza P, Melguizo-Sanchis D, Atanasoai I, Martinez-Gamero C, Román ÁC, Zhu D, Lee DF, Kutter C, Aguilo F. Malla S, et al. EMBO Rep. 2022 Feb 3;23(3):e53191. doi: 10.15252/embr.202153191. Epub 2022 Jan 17. EMBO Rep. 2022. PMID: 35037361 Free PMC article.
Here, we employ multiple functional analyses to characterize its role in mouse embryonic stem cells (ESCs). We find that ZFP207 plays a pivotal role in ESC maintenance, and silencing of Zfp207 leads to severe neuroectodermal differentiation defects. ...Our study exp …
Here, we employ multiple functional analyses to characterize its role in mouse embryonic stem cells (ESCs). We find that ZFP207 plays …
Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.
Dai XX, Xiong H, Zhang M, Sun S, Xiong B. Dai XX, et al. Oncotarget. 2016 May 24;7(21):30155-65. doi: 10.18632/oncotarget.9310. Oncotarget. 2016. PMID: 27177335 Free PMC article.
The precocious polar body extrusion and escape of metaphase I arrest induced by nocodazole treatment in Zfp207-depleted oocytes indicates that Zfp207 is essential for activation of SAC (Spindle Assembly Checkpoint) activity. Notably, we find that Zfp207 binds …
The precocious polar body extrusion and escape of metaphase I arrest induced by nocodazole treatment in Zfp207-depleted oocytes indic …
Aging-related aneuploidy is associated with mitochondrial imbalance and failure of spindle assembly.
Zhang FL, Li WD, Zhu KX, Zhou X, Li L, Lee TL, Shen W. Zhang FL, et al. Cell Death Discov. 2023 Jul 8;9(1):235. doi: 10.1038/s41420-023-01539-2. Cell Death Discov. 2023. PMID: 37422452 Free PMC article.
Moreover, we verified the DEGs related to spindle assembly (such as Naip1, Aspm, Racgap1, Zfp207) by real-time quantitative PCR (RT-qPCR) and checked the mitochondrial dysfunction by JC-1 staining. ...
Moreover, we verified the DEGs related to spindle assembly (such as Naip1, Aspm, Racgap1, Zfp207) by real-time quantitative PCR (RT-q …
BCAS2 is involved in alternative splicing and mouse oocyte development.
Zhang J, Liu W, Li G, Xu C, Nie X, Qin D, Wang Q, Lu X, Liu J, Li L. Zhang J, et al. FASEB J. 2022 Feb;36(2):e22128. doi: 10.1096/fj.202101279R. FASEB J. 2022. PMID: 34972250
The deletion of Bcas2 in mouse oocytes caused alteration in 991 AS events that corresponded to 706 genes, including Pabpc1l, Nobox, Zfp207, Mybl2, Prc1, and Spc25, which were associated with oogenesis and spindle assembly. ...
The deletion of Bcas2 in mouse oocytes caused alteration in 991 AS events that corresponded to 706 genes, including Pabpc1l, Nobox, Zfp20 …
[Cloning and expression analysis of ZFP207 encoding a TFA-type zinc finger protein in rice].
Meng FJ, Huang J, Bao YM, Jiang Y, Zhang HS. Meng FJ, et al. Yi Chuan. 2010 Apr;32(4):387-92. doi: 10.3724/sp.j.1005.2010.00387. Yi Chuan. 2010. PMID: 20423894 Chinese.
The expression pattern of ZFP207 gene was also investigated in various rice tissues at adult stage by RT-PCR and the results showed that ZFP207 was expressed with high levels in culms and leaves, but lower in roots and spikes. Finally, the trans-activation assay in …
The expression pattern of ZFP207 gene was also investigated in various rice tissues at adult stage by RT-PCR and the results showed t …
A Cys2/His2 Zinc Finger Protein Acts as a Repressor of the Green Revolution Gene SD1/OsGA20ox2 in Rice (Oryza sativa L.).
Duan M, Ke XJ, Lan HX, Yuan X, Huang P, Xu ES, Gao XY, Wang RQ, Tang HJ, Zhang HS, Huang J. Duan M, et al. Plant Cell Physiol. 2021 Feb 4;61(12):2055-2066. doi: 10.1093/pcp/pcaa120. Plant Cell Physiol. 2021. PMID: 32966570
ZFP207-overexpression (ZFP207OE) plants displayed semidwarfism phenotype and small grains by modulating cell length. ...Moreover, ZFP207 repressed the expression of OsGA20ox2 via binding to its promoter region. ...
ZFP207-overexpression (ZFP207OE) plants displayed semidwarfism phenotype and small grains by modulating cell length. ...Moreover, …
Candidate genes in ocular dominance plasticity.
Rietman ML, Sommeijer JP; Neuro-Bsik Mouse Phenomics Consortium; Levelt CN, Heimel JA. Rietman ML, et al. Front Neurosci. 2012 Feb 1;6:11. doi: 10.3389/fnins.2012.00011. eCollection 2012. Front Neurosci. 2012. PMID: 22347157 Free PMC article.
More interestingly, the following novel candidate genes were identified: Akap7, Akt1, Camk2d, Cckbr, Cd44, Crim1, Ctdsp2, Dnajc5, Gnai1, Itpka, Mapk8, Nbea, Nfatc3, Nlk, Npy5r, Phf21a, Phip, Ppm1l, Ppp1r1b, Rbbp4, Slc1a3, Slit2, Socs2, Spock3, St8sia1, Zfp207. Whether all …
More interestingly, the following novel candidate genes were identified: Akap7, Akt1, Camk2d, Cckbr, Cd44, Crim1, Ctdsp2, Dnajc5, Gnai1, Itp …