Zhai D - Search Results

1

An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins.

Wei J, Stebbins JL, Kitada S, Dash R, Zhai D, Placzek WJ, Wu B, Rega MF, Zhang Z, Barile E, Yang L, Dahl R, Fisher PB, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. Front Oncol. 2011 Sep 30;1:28. doi: 10.3389/fonc.2011.00028. eCollection 2011. Front Oncol. 2011. PMID: 22655238 Free PMC article.

2

A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy.

Placzek WJ, Wei J, Kitada S, Zhai D, Reed JC, Pellecchia M. Placzek WJ, et al. Among authors: zhai d. Cell Death Dis. 2010 May 6;1(5):e40. doi: 10.1038/cddis.2010.18. Cell Death Dis. 2010. PMID: 21364647 Free PMC article.

3

Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Kitada S, Rega MF, Stebbins JL, Zhai D, Cellitti J, Yuan H, Emdadi A, Dahl R, Zhang Z, Yang L, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. J Med Chem. 2009 Jul 23;52(14):4511-23. doi: 10.1021/jm900472s. J Med Chem. 2009. PMID: 19555126 Free PMC article.

4

BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Stebbins JL, Kitada S, Dash R, Placzek W, Rega MF, Wu B, Cellitti J, Zhai D, Yang L, Dahl R, Fisher PB, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. J Med Chem. 2010 May 27;53(10):4166-76. doi: 10.1021/jm1001265. J Med Chem. 2010. PMID: 20443627 Free PMC article.

5

Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Kitada S, Stebbins JL, Placzek W, Zhai D, Wu B, Rega MF, Zhang Z, Cellitti J, Yang L, Dahl R, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. J Med Chem. 2010 Nov 25;53(22):8000-11. doi: 10.1021/jm100746q. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033669 Free PMC article.

6

Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

Leone M, Zhai D, Sareth S, Kitada S, Reed JC, Pellecchia M. Leone M, et al. Among authors: zhai d. Cancer Res. 2003 Dec 1;63(23):8118-21. Cancer Res. 2003. PMID: 14678963

7

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC. Zhai D, et al. J Biol Chem. 2008 Apr 11;283(15):9580-6. doi: 10.1074/jbc.M708426200. Epub 2008 Jan 4. J Biol Chem. 2008. PMID: 18178565 Free PMC article.

8

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins.

Zhai D, Jin C, Shiau CW, Kitada S, Satterthwait AC, Reed JC. Zhai D, et al. Mol Cancer Ther. 2008 Jun;7(6):1639-46. doi: 10.1158/1535-7163.MCT-07-2373. Mol Cancer Ther. 2008. PMID: 18566235 Free PMC article.

9

Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists.

Wei J, Rega MF, Kitada S, Yuan H, Zhai D, Risbood P, Seltzman HH, Twine CE, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. Cancer Lett. 2009 Jan 8;273(1):107-13. doi: 10.1016/j.canlet.2008.07.031. Epub 2008 Sep 7. Cancer Lett. 2009. PMID: 18782651 Free PMC article.

10

Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins.

Wei J, Kitada S, Rega MF, Emdadi A, Yuan H, Cellitti J, Stebbins JL, Zhai D, Sun J, Yang L, Dahl R, Zhang Z, Wu B, Wang S, Reed TA, Wang HG, Lawrence N, Sebti S, Reed JC, Pellecchia M. Wei J, et al. Among authors: zhai d. Mol Cancer Ther. 2009 Apr;8(4):904-13. doi: 10.1158/1535-7163.MCT-08-1050. Mol Cancer Ther. 2009. PMID: 19372563 Free PMC article.

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