Zhang C - Search Results

1

TrkB kinase activity maintains synaptic function and structural integrity at adult neuromuscular junctions.

Mantilla CB, Stowe JM, Sieck DC, Ermilov LG, Greising SM, Zhang C, Shokat KM, Sieck GC. Mantilla CB, et al. Among authors: zhang c. J Appl Physiol (1985). 2014 Oct 15;117(8):910-20. doi: 10.1152/japplphysiol.01386.2013. Epub 2014 Aug 28. J Appl Physiol (1985). 2014. PMID: 25170066 Free PMC article.

2

Generation of a novel system for studying spleen tyrosine kinase function in macrophages and B cells.

Miller AL, Zhang C, Shokat KM, Lowell CA. Miller AL, et al. Among authors: zhang c. J Immunol. 2009 Jan 15;182(2):988-98. doi: 10.4049/jimmunol.182.2.988. J Immunol. 2009. PMID: 19124742 Free PMC article.

3

Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach.

Fan QW, Specht KM, Zhang C, Goldenberg DD, Shokat KM, Weiss WA. Fan QW, et al. Among authors: zhang c. Cancer Res. 2003 Dec 15;63(24):8930-8. Cancer Res. 2003. PMID: 14695210

4

Structural bioinformatics-based design of selective, irreversible kinase inhibitors.

Cohen MS, Zhang C, Shokat KM, Taunton J. Cohen MS, et al. Among authors: zhang c. Science. 2005 May 27;308(5726):1318-21. doi: 10.1126/science1108367. Science. 2005. PMID: 15919995 Free PMC article.

5

GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor.

Chou WH, Wang D, McMahon T, Qi ZH, Song M, Zhang C, Shokat KM, Messing RO. Chou WH, et al. Among authors: zhang c. J Neurosci. 2010 Oct 20;30(42):13955-65. doi: 10.1523/JNEUROSCI.0270-10.2010. J Neurosci. 2010. PMID: 20962217 Free PMC article.

6

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity.

Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A. Au-Yeung BB, et al. Among authors: zhang c. Nat Immunol. 2010 Dec;11(12):1085-92. doi: 10.1038/ni.1955. Epub 2010 Oct 31. Nat Immunol. 2010. PMID: 21037577 Free PMC article.

7

TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex.

Yoshii A, Murata Y, Kim J, Zhang C, Shokat KM, Constantine-Paton M. Yoshii A, et al. Among authors: zhang c. J Neurosci. 2011 Aug 17;31(33):11894-904. doi: 10.1523/JNEUROSCI.2190-11.2011. J Neurosci. 2011. PMID: 21849550 Free PMC article.

8

Genetic deletion of trkB.T1 increases neuromuscular function.

Dorsey SG, Lovering RM, Renn CL, Leitch CC, Liu X, Tallon LJ, Sadzewicz LD, Pratap A, Ott S, Sengamalay N, Jones KM, Barrick C, Fulgenzi G, Becker J, Voelker K, Talmadge R, Harvey BK, Wyatt RM, Vernon-Pitts E, Zhang C, Shokat K, Fraser-Liggett C, Balice-Gordon RJ, Tessarollo L, Ward CW. Dorsey SG, et al. Among authors: zhang c. Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C141-53. doi: 10.1152/ajpcell.00469.2010. Epub 2011 Oct 5. Am J Physiol Cell Physiol. 2012. PMID: 21865582 Free PMC article.

9

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.

Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. Horiuchi D, et al. Among authors: zhang c. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1019-27. doi: 10.1073/pnas.1111317109. Epub 2012 Apr 3. Proc Natl Acad Sci U S A. 2012. PMID: 22474407 Free PMC article.

10

Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling.

Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. Tan YX, et al. Among authors: zhang c. Nat Immunol. 2014 Feb;15(2):186-94. doi: 10.1038/ni.2772. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317039 Free PMC article.

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