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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 2
1986 3
1987 2
1988 1
1989 1
1991 3
1992 2
1993 1
1994 2
1995 1
1996 1
1997 1
1999 2
2002 2
2003 7
2004 9
2005 6
2006 3
2007 7
2008 9
2009 6
2010 10
2011 17
2012 25
2013 16
2014 15
2015 14
2016 14
2017 17
2018 21
2019 27
2020 33
2021 31
2022 38
2023 18
2024 25

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361 results

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Page 1
Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Ma T, Tian X, Zhang B, Li M, Wang Y, Yang C, Wu J, Wei X, Qu Q, Yu Y, Long S, Feng JW, Li C, Zhang C, Xie C, Wu Y, Xu Z, Chen J, Yu Y, Huang X, He Y, Yao L, Zhang L, Zhu M, Wang W, Wang ZC, Zhang M, Bao Y, Jia W, Lin SY, Ye Z, Piao HL, Deng X, Zhang CS, Lin SC. Ma T, et al. Among authors: zhang cs. Nature. 2022 Mar;603(7899):159-165. doi: 10.1038/s41586-022-04431-8. Epub 2022 Feb 23. Nature. 2022. PMID: 35197629 Free PMC article.
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Zhang CS, Hawley SA, Zong Y, Li M, Wang Z, Gray A, Ma T, Cui J, Feng JW, Zhu M, Wu YQ, Li TY, Ye Z, Lin SY, Yin H, Piao HL, Hardie DG, Lin SC. Zhang CS, et al. Nature. 2017 Aug 3;548(7665):112-116. doi: 10.1038/nature23275. Epub 2017 Jul 19. Nature. 2017. PMID: 28723898 Free PMC article.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC. Zhang CS, et al. Nat Metab. 2022 Oct;4(10):1369-1401. doi: 10.1038/s42255-022-00640-7. Epub 2022 Oct 10. Nat Metab. 2022. PMID: 36217034 Free PMC article.
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function.
Xu X, Ding G, Liu C, Ding Y, Chen X, Huang X, Zhang CS, Lu S, Zhang Y, Huang Y, Chen Z, Wei W, Liao L, Lin SH, Li J, Liu W, Li J, Lin SC, Ma X, Wong J. Xu X, et al. Among authors: zhang cs. Cell Res. 2022 Jan;32(1):54-71. doi: 10.1038/s41422-021-00565-y. Epub 2021 Sep 24. Cell Res. 2022. PMID: 34561619 Free PMC article.
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Wu YQ, Zhang CS, Xiong J, Cai DQ, Wang CZ, Wang Y, Liu YH, Wang Y, Li Y, Wu J, Wu J, Lan B, Wang X, Chen S, Cao X, Wei X, Hu HH, Guo H, Yu Y, Ghafoor A, Xie C, Wu Y, Xu Z, Zhang C, Zhu M, Huang X, Sun X, Lin SY, Piao HL, Zhou J, Lin SC. Wu YQ, et al. Among authors: zhang cs. Cell Res. 2023 Nov;33(11):835-850. doi: 10.1038/s41422-023-00874-4. Epub 2023 Sep 19. Cell Res. 2023. PMID: 37726403 Free PMC article.
AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.
Zhang Q, Liu S, Zhang CS, Wu Q, Yu X, Zhou R, Meng F, Wang A, Zhang F, Chen S, Wang X, Li L, Huang J, Huang YW, Zou J, Qin J, Liang T, Feng XH, Lin SC, Xu P. Zhang Q, et al. Among authors: zhang cs. Mol Cell. 2022 Dec 1;82(23):4519-4536.e7. doi: 10.1016/j.molcel.2022.10.026. Epub 2022 Nov 15. Mol Cell. 2022. PMID: 36384137 Free article.
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Li M, Zhang CS, Zong Y, Feng JW, Ma T, Hu M, Lin Z, Li X, Xie C, Wu Y, Jiang D, Li Y, Zhang C, Tian X, Wang W, Yang Y, Chen J, Cui J, Wu YQ, Chen X, Liu QF, Wu J, Lin SY, Ye Z, Liu Y, Piao HL, Yu L, Zhou Z, Xie XS, Hardie DG, Lin SC. Li M, et al. Among authors: zhang cs. Cell Metab. 2019 Sep 3;30(3):508-524.e12. doi: 10.1016/j.cmet.2019.05.018. Epub 2019 Jun 13. Cell Metab. 2019. PMID: 31204282 Free PMC article.
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, Li J, Li Q, Zhong Z, Zhang M, Yuan Q, Hu H, Wang S, Hu MM, Cai C, Wu GS, Jiang C, Zhang YL, Zhang CS, Zhang J. Jiang W, et al. Among authors: zhang cs. EMBO J. 2023 Oct 16;42(20):e113743. doi: 10.15252/embj.2023113743. Epub 2023 Sep 4. EMBO J. 2023. PMID: 37661833 Free PMC article.
361 results