Zhang H - Search Results

1

Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model.

Shan L, Yang HC, Rabi SA, Bravo HC, Shroff NS, Irizarry RA, Zhang H, Margolick JB, Siliciano JD, Siliciano RF. Shan L, et al. Among authors: zhang h. J Virol. 2011 Jun;85(11):5384-93. doi: 10.1128/JVI.02536-10. Epub 2011 Mar 23. J Virol. 2011. PMID: 21430059 Free PMC article.

2

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation.

Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Yang HC, et al. Among authors: zhang h. J Clin Invest. 2009 Nov;119(11):3473-86. doi: 10.1172/JCI39199. Epub 2009 Oct 1. J Clin Invest. 2009. PMID: 19805909 Free PMC article.

3

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.

Xing S, Bullen CK, Shroff NS, Shan L, Yang HC, Manucci JL, Bhat S, Zhang H, Margolick JB, Quinn TC, Margolis DM, Siliciano JD, Siliciano RF. Xing S, et al. Among authors: zhang h. J Virol. 2011 Jun;85(12):6060-4. doi: 10.1128/JVI.02033-10. Epub 2011 Apr 6. J Virol. 2011. PMID: 21471244 Free PMC article.

4

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.

Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Xing S, et al. Among authors: zhang h. J Antimicrob Chemother. 2012 Feb;67(2):398-403. doi: 10.1093/jac/dkr496. Epub 2011 Dec 7. J Antimicrob Chemother. 2012. PMID: 22160146 Free PMC article.

5

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation.

Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, Zhang H, Margolick JB, Blankson JN, Siliciano RF. Shan L, et al. Among authors: zhang h. Immunity. 2012 Mar 23;36(3):491-501. doi: 10.1016/j.immuni.2012.01.014. Epub 2012 Mar 8. Immunity. 2012. PMID: 22406268 Free PMC article.

6

A novel PCR assay for quantification of HIV-1 RNA.

Shan L, Rabi SA, Laird GM, Eisele EE, Zhang H, Margolick JB, Siliciano RF. Shan L, et al. Among authors: zhang h. J Virol. 2013 Jun;87(11):6521-5. doi: 10.1128/JVI.00006-13. Epub 2013 Mar 27. J Virol. 2013. PMID: 23536672 Free PMC article.

7

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells.

Shan L, Xing S, Yang HC, Zhang H, Margolick JB, Siliciano RF. Shan L, et al. Among authors: zhang h. J Antimicrob Chemother. 2014 Jan;69(1):28-33. doi: 10.1093/jac/dkt338. Epub 2013 Sep 1. J Antimicrob Chemother. 2014. PMID: 23999005 Free PMC article.

8

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.

Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. Deng K, et al. Among authors: zhang h. Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7. Nature. 2015. PMID: 25561180 Free PMC article.

9

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4⁺ T Cells Permissive for Latent HIV-1 Infection.

Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, Ke R, Flavell RA, Siliciano JD, Siliciano RF. Shan L, et al. Among authors: zhang h. Immunity. 2017 Oct 17;47(4):766-775.e3. doi: 10.1016/j.immuni.2017.09.014. Immunity. 2017. PMID: 29045905 Free PMC article.

10

A novel assay allows genotyping of the latent reservoir for human immunodeficiency virus type 1 in the resting CD4+ T cells of viremic patients.

Monie D, Simmons RP, Nettles RE, Kieffer TL, Zhou Y, Zhang H, Karmon S, Ingersoll R, Chadwick K, Zhang H, Margolick JB, Quinn TC, Ray SC, Wind-Rotolo M, Miller M, Persaud D, Siliciano RF. Monie D, et al. Among authors: zhang h. J Virol. 2005 Apr;79(8):5185-202. doi: 10.1128/JVI.79.8.5185-5202.2005. J Virol. 2005. PMID: 15795302 Free PMC article.

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