Zhang H - Search Results

1

Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells.

Kim C, Hu B, Jadhav RR, Jin J, Zhang H, Cavanagh MM, Akondy RS, Ahmed R, Weyand CM, Goronzy JJ. Kim C, et al. Among authors: zhang h. Cell Rep. 2018 Nov 20;25(8):2148-2162.e5. doi: 10.1016/j.celrep.2018.10.074. Cell Rep. 2018. PMID: 30463012 Free PMC article.

2

Metabolic reprogramming in memory CD4 T cell responses of old adults.

Yanes RE, Zhang H, Shen Y, Weyand CM, Goronzy JJ. Yanes RE, et al. Among authors: zhang h. Clin Immunol. 2019 Oct;207:58-67. doi: 10.1016/j.clim.2019.07.003. Epub 2019 Jul 4. Clin Immunol. 2019. PMID: 31279855 Free PMC article.

3

FOXO1 deficiency impairs proteostasis in aged T cells.

Jin J, Li X, Hu B, Kim C, Cao W, Zhang H, Weyand CM, Goronzy JJ. Jin J, et al. Among authors: zhang h. Sci Adv. 2020 Apr 22;6(17):eaba1808. doi: 10.1126/sciadv.aba1808. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32494657 Free PMC article.

4

The GSK3β-β-catenin-TCF1 pathway improves naive T cell activation in old adults by upregulating miR-181a.

Ye Z, Gould TM, Zhang H, Jin J, Weyand CM, Goronzy JJ. Ye Z, et al. Among authors: zhang h. NPJ Aging Mech Dis. 2021 Feb 8;7(1):4. doi: 10.1038/s41514-021-00056-9. NPJ Aging Mech Dis. 2021. PMID: 33558531 Free PMC article.

5

Hallmarks of the aging T-cell system.

Zhang H, Weyand CM, Goronzy JJ. Zhang H, et al. FEBS J. 2021 Dec;288(24):7123-7142. doi: 10.1111/febs.15770. Epub 2021 Mar 3. FEBS J. 2021. PMID: 33590946 Free PMC article. Review.

6

Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals.

Jin J, Kim C, Xia Q, Gould TM, Cao W, Zhang H, Li X, Weiskopf D, Grifoni A, Sette A, Weyand CM, Goronzy JJ. Jin J, et al. Among authors: zhang h. Sci Immunol. 2021 Jun 18;6(60):eabg0791. doi: 10.1126/sciimmunol.abg0791. Sci Immunol. 2021. PMID: 34145066 Free PMC article.

7

Understanding T cell aging to improve anti-viral immunity.

Zhang H, Weyand CM, Goronzy JJ, Gustafson CE. Zhang H, et al. Curr Opin Virol. 2021 Dec;51:127-133. doi: 10.1016/j.coviro.2021.09.017. Epub 2021 Oct 21. Curr Opin Virol. 2021. PMID: 34688983 Free PMC article. Review.

8

The cell-surface 5'-nucleotidase CD73 defines a functional T memory cell subset that declines with age.

Fang F, Cao W, Zhu W, Lam N, Li L, Gaddam S, Wang Y, Kim C, Lambert S, Zhang H, Hu B, Farber DL, Weyand CM, Goronzy JJ. Fang F, et al. Among authors: zhang h. Cell Rep. 2021 Nov 9;37(6):109981. doi: 10.1016/j.celrep.2021.109981. Cell Rep. 2021. PMID: 34758299 Free PMC article.

9

Lysosomes in T Cell Immunity and Aging.

Jin J, Zhang H, Weyand CM, Goronzy JJ. Jin J, et al. Among authors: zhang h. Front Aging. 2021 Dec 9;2:809539. doi: 10.3389/fragi.2021.809539. eCollection 2021. Front Aging. 2021. PMID: 35822050 Free PMC article. Review.

10

The influence of three-dimensional structure on naïve T cell homeostasis and aging.

Lambert S, Cao W, Zhang H, Colville A, Liu JY, Weyand CM, Goronzy JJ, Gustafson CE. Lambert S, et al. Among authors: zhang h. Front Aging. 2022 Nov 7;3:1045648. doi: 10.3389/fragi.2022.1045648. eCollection 2022. Front Aging. 2022. PMID: 36419548 Free PMC article.

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