Zhang JG - Search Results

1

The LIF receptor antagonist PEGLA is effectively delivered to the uterine endometrium and blocks LIF activity in cynomolgus monkeys.

Aschenbach LC, Hester KE, McCann NC, Zhang JG, Dimitriadis E, Duffy DM. Aschenbach LC, et al. Among authors: zhang jg. Contraception. 2013 Jun;87(6):813-23. doi: 10.1016/j.contraception.2012.09.032. Epub 2012 Oct 31. Contraception. 2013. PMID: 23121824

2

Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy.

White CA, Zhang JG, Salamonsen LA, Baca M, Fairlie WD, Metcalf D, Nicola NA, Robb L, Dimitriadis E. White CA, et al. Among authors: zhang jg. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19357-62. doi: 10.1073/pnas.0710110104. Epub 2007 Nov 27. Proc Natl Acad Sci U S A. 2007. PMID: 18042698 Free PMC article.

3

Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.

Menkhorst E, Zhang JG, Sims NA, Morgan PO, Soo P, Poulton IJ, Metcalf D, Alexandrou E, Gresle M, Salamonsen LA, Butzkueven H, Nicola NA, Dimitriadis E. Menkhorst E, et al. Among authors: zhang jg. PLoS One. 2011;6(5):e19665. doi: 10.1371/journal.pone.0019665. Epub 2011 May 18. PLoS One. 2011. PMID: 21611124 Free PMC article.

4

Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT.

Lalitkumar S, Boggavarapu NR, Menezes J, Dimitriadis E, Zhang JG, Nicola NA, Gemzell-Danielsson K, Lalitkumar LP. Lalitkumar S, et al. Among authors: zhang jg. Fertil Steril. 2013 Oct;100(4):1160-9. doi: 10.1016/j.fertnstert.2013.06.023. Epub 2013 Jul 19. Fertil Steril. 2013. PMID: 23876532 Free article.

5

Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss.

Winship A, Correia J, Krishnan T, Menkhorst E, Cuman C, Zhang JG, Nicola NA, Dimitriadis E. Winship A, et al. Among authors: zhang jg. Sci Rep. 2015 Aug 14;5:13237. doi: 10.1038/srep13237. Sci Rep. 2015. PMID: 26272398 Free PMC article.

6

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice.

Winship A, Correia J, Zhang JG, Nicola NA, Dimitriadis E. Winship A, et al. Among authors: zhang jg. PLoS One. 2015 Oct 19;10(10):e0129110. doi: 10.1371/journal.pone.0129110. eCollection 2015. PLoS One. 2015. PMID: 26479247 Free PMC article.

7

Interleukin-11 alters placentation and causes preeclampsia features in mice.

Winship AL, Koga K, Menkhorst E, Van Sinderen M, Rainczuk K, Nagai M, Cuman C, Yap J, Zhang JG, Simmons D, Young MJ, Dimitriadis E. Winship AL, et al. Among authors: zhang jg. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15928-33. doi: 10.1073/pnas.1515076112. Epub 2015 Dec 11. Proc Natl Acad Sci U S A. 2015. PMID: 26655736 Free PMC article.

8

Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.

Menkhorst E, Zhou W, Santos L, Zhang JG, St-Pierre Y, Young MJ, Dimitriadis E. Menkhorst E, et al. Among authors: zhang jg. Pregnancy Hypertens. 2022 Dec;30:130-136. doi: 10.1016/j.preghy.2022.09.008. Epub 2022 Sep 26. Pregnancy Hypertens. 2022. PMID: 36183583

9

IL11 activates the placental inflammasome to drive preeclampsia.

Menkhorst E, Santos LL, Zhou W, Yang G, Winship AL, Rainczuk KE, Nguyen P, Zhang JG, Moore P, Williams M, Lê Cao KA, Mansell A, Dimitriadis E. Menkhorst E, et al. Among authors: zhang jg. Front Immunol. 2023 May 24;14:1175926. doi: 10.3389/fimmu.2023.1175926. eCollection 2023. Front Immunol. 2023. PMID: 37292200 Free PMC article.

10

An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.

Huyton T, Zhang JG, Luo CS, Lou MZ, Hilton DJ, Nicola NA, Garrett TP. Huyton T, et al. Among authors: zhang jg. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12737-42. doi: 10.1073/pnas.0705577104. Epub 2007 Jul 24. Proc Natl Acad Sci U S A. 2007. PMID: 17652170 Free PMC article.

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