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Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.
Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E. Schug ZT, et al. Among authors: zhang q. Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002. Cancer Cell. 2015. PMID: 25584894 Free PMC article.
Lipidomics in the analysis of malignancy.
Zhang Q, Wakelam MJ. Zhang Q, et al. Adv Biol Regul. 2014 Jan;54:93-8. doi: 10.1016/j.jbior.2013.11.001. Epub 2013 Nov 18. Adv Biol Regul. 2014. PMID: 24332194 Review.
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.
Peck B, Schug ZT, Zhang Q, Dankworth B, Jones DT, Smethurst E, Patel R, Mason S, Jiang M, Saunders R, Howell M, Mitter R, Spencer-Dene B, Stamp G, McGarry L, James D, Shanks E, Aboagye EO, Critchlow SE, Leung HY, Harris AL, Wakelam MJO, Gottlieb E, Schulze A. Peck B, et al. Among authors: zhang q. Cancer Metab. 2016 Apr 1;4:6. doi: 10.1186/s40170-016-0146-8. eCollection 2016. Cancer Metab. 2016. PMID: 27042297 Free PMC article.
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.
Casciano JC, Perry C, Cohen-Nowak AJ, Miller KD, Vande Voorde J, Zhang Q, Chalmers S, Sandison ME, Liu Q, Hedley A, McBryan T, Tang HY, Gorman N, Beer T, Speicher DW, Adams PD, Liu X, Schlegel R, McCarron JG, Wakelam MJO, Gottlieb E, Kossenkov AV, Schug ZT. Casciano JC, et al. Among authors: zhang q. Br J Cancer. 2020 Mar;122(6):868-884. doi: 10.1038/s41416-019-0711-3. Epub 2020 Jan 16. Br J Cancer. 2020. PMID: 31942031 Free PMC article.
Runx regulation of sphingolipid metabolism and survival signaling.
Kilbey A, Terry A, Jenkins A, Borland G, Zhang Q, Wakelam MJ, Cameron ER, Neil JC. Kilbey A, et al. Among authors: zhang q. Cancer Res. 2010 Jul 15;70(14):5860-9. doi: 10.1158/0008-5472.CAN-10-0726. Epub 2010 Jun 29. Cancer Res. 2010. PMID: 20587518 Free PMC article.
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