Zhen G - Search Results

1

Angiogenesis stimulated by elevated PDGF-BB in subchondral bone contributes to osteoarthritis development.

Su W, Liu G, Liu X, Zhou Y, Sun Q, Zhen G, Wang X, Hu Y, Gao P, Demehri S, Cao X, Wan M. Su W, et al. Among authors: zhen g. JCI Insight. 2020 Apr 23;5(8):e135446. doi: 10.1172/jci.insight.135446. JCI Insight. 2020. PMID: 32208385 Free PMC article.

2

Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis.

Zhen G, Cao X. Zhen G, et al. Trends Pharmacol Sci. 2014 May;35(5):227-36. doi: 10.1016/j.tips.2014.03.005. Epub 2014 Apr 15. Trends Pharmacol Sci. 2014. PMID: 24745631 Free PMC article. Review.

3

Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain.

Zhu S, Zhu J, Zhen G, Hu Y, An S, Li Y, Zheng Q, Chen Z, Yang Y, Wan M, Skolasky RL, Cao Y, Wu T, Gao B, Yang M, Gao M, Kuliwaba J, Ni S, Wang L, Wu C, Findlay D, Eltzschig HK, Ouyang HW, Crane J, Zhou FQ, Guan Y, Dong X, Cao X. Zhu S, et al. Among authors: zhen g. J Clin Invest. 2019 Mar 1;129(3):1076-1093. doi: 10.1172/JCI121561. Epub 2019 Feb 4. J Clin Invest. 2019. PMID: 30530994 Free PMC article.

4

Aberrant subchondral osteoblastic metabolism modifies Na_V1.8 for osteoarthritis.

Zhu J, Zhen G, An S, Wang X, Wan M, Li Y, Chen Z, Guan Y, Dong X, Hu Y, Cao X. Zhu J, et al. Among authors: zhen g. Elife. 2020 May 22;9:e57656. doi: 10.7554/eLife.57656. Elife. 2020. PMID: 32441256 Free PMC article.

5

Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice.

Sun Q, Zhen G, Li TP, Guo Q, Li Y, Su W, Xue P, Wang X, Wan M, Guan Y, Dong X, Li S, Cai M, Cao X. Sun Q, et al. Among authors: zhen g. Elife. 2021 Mar 1;10:e66532. doi: 10.7554/eLife.66532. Elife. 2021. PMID: 33646122 Free PMC article.

6

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.

Zhen G, Wen C, Jia X, Li Y, Crane JL, Mears SC, Askin FB, Frassica FJ, Chang W, Yao J, Carrino JA, Cosgarea A, Artemov D, Chen Q, Zhao Z, Zhou X, Riley L, Sponseller P, Wan M, Lu WW, Cao X. Zhen G, et al. Nat Med. 2013 Jun;19(6):704-12. doi: 10.1038/nm.3143. Epub 2013 May 19. Nat Med. 2013. PMID: 23685840 Free PMC article.

7

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis.

Xie H, Cui Z, Wang L, Xia Z, Hu Y, Xian L, Li C, Xie L, Crane J, Wan M, Zhen G, Bian Q, Yu B, Chang W, Qiu T, Pickarski M, Duong LT, Windle JJ, Luo X, Liao E, Cao X. Xie H, et al. Among authors: zhen g. Nat Med. 2014 Nov;20(11):1270-8. doi: 10.1038/nm.3668. Epub 2014 Oct 5. Nat Med. 2014. PMID: 25282358 Free PMC article.

8

Aberrant Activation of TGF-β in Subchondral Bone at the Onset of Rheumatoid Arthritis Joint Destruction.

Xu X, Zheng L, Bian Q, Xie L, Liu W, Zhen G, Crane JL, Zhou X, Cao X. Xu X, et al. Among authors: zhen g. J Bone Miner Res. 2015 Nov;30(11):2033-43. doi: 10.1002/jbmr.2550. Epub 2015 Jun 8. J Bone Miner Res. 2015. PMID: 25967237 Free PMC article.

9

Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone.

Cui Z, Crane J, Xie H, Jin X, Zhen G, Li C, Xie L, Wang L, Bian Q, Qiu T, Wan M, Xie M, Ding S, Yu B, Cao X. Cui Z, et al. Among authors: zhen g. Ann Rheum Dis. 2016 Sep;75(9):1714-21. doi: 10.1136/annrheumdis-2015-207923. Epub 2015 Oct 15. Ann Rheum Dis. 2016. PMID: 26470720 Free PMC article.

10

Systemic neutralization of TGF-β attenuates osteoarthritis.

Xie L, Tintani F, Wang X, Li F, Zhen G, Qiu T, Wan M, Crane J, Chen Q, Cao X. Xie L, et al. Among authors: zhen g. Ann N Y Acad Sci. 2016 Jul;1376(1):53-64. doi: 10.1111/nyas.13000. Epub 2016 Feb 2. Ann N Y Acad Sci. 2016. PMID: 26837060 Free PMC article.

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