Zhou YL - Search Results

1

Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer.

Zou LJ, Xiang QP, Xue XQ, Zhang C, Li CC, Wang C, Li Q, Wang R, Wu S, Zhou YL, Zhang Y, Xu Y. Zou LJ, et al. Among authors: zhou yl. Acta Pharmacol Sin. 2019 Nov;40(11):1436-1447. doi: 10.1038/s41401-019-0237-5. Epub 2019 May 16. Acta Pharmacol Sin. 2019. PMID: 31097763 Free PMC article.

2

Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivation.

Lv M, Zhang B, Shi Y, Han Z, Zhang Y, Zhou Y, Zhang W, Niu J, Yu XF. Lv M, et al. Sci Rep. 2015 Jun 29;5:11736. doi: 10.1038/srep11736. Sci Rep. 2015. PMID: 26119070 Free PMC article.

3

Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation.

Xue X, Zhang Y, Liu Z, Song M, Xing Y, Xiang Q, Wang Z, Tu Z, Zhou Y, Ding K, Xu Y. Xue X, et al. J Med Chem. 2016 Feb 25;59(4):1565-79. doi: 10.1021/acs.jmedchem.5b01511. Epub 2016 Jan 12. J Med Chem. 2016. PMID: 26731490

4

Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new RORγ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation.

Song Y, Xue X, Wu X, Wang R, Xing Y, Yan W, Zhou Y, Qian CN, Zhang Y, Xu Y. Song Y, et al. Eur J Med Chem. 2016 Jun 30;116:13-26. doi: 10.1016/j.ejmech.2016.03.052. Epub 2016 Mar 21. Eur J Med Chem. 2016. PMID: 27043267

5

Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)-ones as RORc inverse agonists.

Wu XS, Wang R, Xing YL, Xue XQ, Zhang Y, Lu YZ, Song Y, Luo XY, Wu C, Zhou YL, Jiang JQ, Xu Y. Wu XS, et al. Among authors: zhou yl. Acta Pharmacol Sin. 2016 Nov;37(11):1516-1524. doi: 10.1038/aps.2016.32. Epub 2016 Jul 4. Acta Pharmacol Sin. 2016. PMID: 27374490 Free PMC article.

6

Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.

Xiang Q, Wang C, Zhang Y, Xue X, Song M, Zhang C, Li C, Wu C, Li K, Hui X, Zhou Y, Smaill JB, Patterson AV, Wu D, Ding K, Xu Y. Xiang Q, et al. Eur J Med Chem. 2018 Mar 10;147:238-252. doi: 10.1016/j.ejmech.2018.01.087. Epub 2018 Feb 6. Eur J Med Chem. 2018. PMID: 29448139

7

Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer.

Xiang Q, Zhang Y, Li J, Xue X, Wang C, Song M, Zhang C, Wang R, Li C, Wu C, Zhou Y, Yang X, Li G, Ding K, Xu Y. Xiang Q, et al. ACS Med Chem Lett. 2018 Feb 13;9(3):262-267. doi: 10.1021/acsmedchemlett.8b00003. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541371 Free PMC article.

8

Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC).

Zhang M, Zhang Y, Song M, Xue X, Wang J, Wang C, Zhang C, Li C, Xiang Q, Zou L, Wu X, Wu C, Dong B, Xue W, Zhou Y, Chen H, Wu D, Ding K, Xu Y. Zhang M, et al. J Med Chem. 2018 Apr 12;61(7):3037-3058. doi: 10.1021/acs.jmedchem.8b00103. Epub 2018 Apr 3. J Med Chem. 2018. PMID: 29566488

9

Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.

Li J, Zhang C, Xu H, Wang C, Dong R, Shen H, Zhuang X, Chen X, Li Q, Lu J, Zhang M, Wu X, Loomes KM, Zhou Y, Zhang Y, Liu J, Xu Y. Li J, et al. J Med Chem. 2022 Apr 14;65(7):5760-5799. doi: 10.1021/acs.jmedchem.2c00100. Epub 2022 Mar 25. J Med Chem. 2022. PMID: 35333526

10

[Detection of antigen-receptor gene rearrangement clonality for diagnosis of lymphoma].

Li XB, Wang YP, Gao JN, Wang C, Zou YB, Wang HY, Zhou YL, Duan XM. Li XB, et al. Among authors: zhou yl. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Aug;20(4):906-11. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012. PMID: 22931652 Chinese.

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