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Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF. Niu NK, et al. Among authors: zhou zw, zhou sf. Drug Des Devel Ther. 2015 Mar 12;9:1555-84. doi: 10.2147/DDDT.S74197. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25792811 Free PMC article.
Identification of drugs that interact with herbs in drug development.
Zhou SF, Zhou ZW, Li CG, Chen X, Yu X, Xue CC, Herington A. Zhou SF, et al. Among authors: zhou zw. Drug Discov Today. 2007 Aug;12(15-16):664-73. doi: 10.1016/j.drudis.2007.06.004. Epub 2007 Jul 30. Drug Discov Today. 2007. PMID: 17706549 Free article. Review.
509 results