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A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.
Nishikawa T, Bellance N, Damm A, Bing H, Zhu Z, Handa K, Yovchev MI, Sehgal V, Moss TJ, Oertel M, Ram PT, Pipinos II, Soto-Gutierrez A, Fox IJ, Nagrath D. Nishikawa T, et al. Among authors: zhu z. J Hepatol. 2014 Jun;60(6):1203-11. doi: 10.1016/j.jhep.2014.02.014. Epub 2014 Feb 26. J Hepatol. 2014. PMID: 24583248 Free PMC article.
Mitochondriopathy of peripheral arterial disease.
Makris KI, Nella AA, Zhu Z, Swanson SA, Casale GP, Gutti TL, Judge AR, Pipinos II. Makris KI, et al. Among authors: zhu z. Vascular. 2007 Nov-Dec;15(6):336-43. doi: 10.2310/6670.2007.00054. Vascular. 2007. PMID: 18053417 Review.
Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage.
Pipinos II, Swanson SA, Zhu Z, Nella AA, Weiss DJ, Gutti TL, McComb RD, Baxter BT, Lynch TG, Casale GP. Pipinos II, et al. Among authors: zhu z. Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R290-6. doi: 10.1152/ajpregu.90374.2008. Epub 2008 May 14. Am J Physiol Regul Integr Comp Physiol. 2008. PMID: 18480238 Free PMC article.
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