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Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.
Wargnies M, Bertiaux E, Cahoreau E, Ziebart N, Crouzols A, Morand P, Biran M, Allmann S, Hubert J, Villafraz O, Millerioux Y, Plazolles N, Asencio C, Rivière L, Rotureau B, Boshart M, Portais JC, Bringaud F. Wargnies M, et al. Among authors: ziebart n. PLoS Pathog. 2018 Dec 17;14(12):e1007502. doi: 10.1371/journal.ppat.1007502. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30557412 Free PMC article.
Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei.
Allmann S, Mazet M, Ziebart N, Bouyssou G, Fouillen L, Dupuy JW, Bonneu M, Moreau P, Bringaud F, Boshart M. Allmann S, et al. Among authors: ziebart n. PLoS One. 2014 Dec 10;9(12):e114628. doi: 10.1371/journal.pone.0114628. eCollection 2014. PLoS One. 2014. PMID: 25493940 Free PMC article.
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.
Specker E, Matthes S, Wesolowski R, Schütz A, Grohmann M, Alenina N, Pleimes D, Mallow K, Neuenschwander M, Gogolin A, Weise M, Pfeifer J, Ziebart N, Heinemann U, von Kries JP, Nazaré M, Bader M. Specker E, et al. Among authors: ziebart n. J Med Chem. 2022 Aug 25;65(16):11126-11149. doi: 10.1021/acs.jmedchem.2c00598. Epub 2022 Aug 3. J Med Chem. 2022. PMID: 35921615
From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement.
Mostinski Y, Heynen GJJE, López-Alberca MP, Paul J, Miksche S, Radetzki S, Schaller D, Shanina E, Seyffarth C, Kolomeets Y, Ziebart N, de Schryver J, Oestreich S, Neuenschwander M, Roske Y, Heinemann U, Rademacher C, Volkamer A, von Kries JP, Birchmeier W, Nazaré M. Mostinski Y, et al. Among authors: ziebart n. J Med Chem. 2020 Dec 10;63(23):14780-14804. doi: 10.1021/acs.jmedchem.0c01265. Epub 2020 Nov 19. J Med Chem. 2020. PMID: 33210922
Allosteric Inhibition of a Mammalian Lectin.
Aretz J, Anumala UR, Fuchsberger FF, Molavi N, Ziebart N, Zhang H, Nazaré M, Rademacher C. Aretz J, et al. Among authors: ziebart n. J Am Chem Soc. 2018 Nov 7;140(44):14915-14925. doi: 10.1021/jacs.8b08644. Epub 2018 Oct 24. J Am Chem Soc. 2018. PMID: 30303367