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Identification of ZMYND19 as a novel biomarker of colorectal cancer: RNA-sequencing and machine learning analysis.
Khalili-Tanha G, Mohit R, Asadnia A, Khazaei M, Dashtiahangar M, Maftooh M, Nassiri M, Hassanian SM, Ghayour-Mobarhan M, Kiani MA, Ferns GA, Batra J, Nazari E, Avan A. Khalili-Tanha G, et al. J Cell Commun Signal. 2023 Dec;17(4):1469-1485. doi: 10.1007/s12079-023-00779-2. Epub 2023 Jul 10. J Cell Commun Signal. 2023. PMID: 37428302 Free PMC article.
Furthermore, the survival analysis identified NOP58, OSBPL3, DNAJC2, and ZMYND19 as prognostic markers. The combineROC curve analysis indicated that the combination of C10orf2 -PPAT- ZMYND19 can be considered as diagnostic markers with sensitivity, specificity, and …
Furthermore, the survival analysis identified NOP58, OSBPL3, DNAJC2, and ZMYND19 as prognostic markers. The combineROC curve analysis …
LncRNA FABP5P3/miR-589-5p/ZMYND19 axis contributes to hepatocellular carcinoma cell proliferation, migration and invasion.
Zhu Q, Luo Z, Lu G, Gui F, Wu J, Li F, Ni Y. Zhu Q, et al. Biochem Biophys Res Commun. 2018 Apr 6;498(3):551-558. doi: 10.1016/j.bbrc.2018.03.017. Epub 2018 Mar 6. Biochem Biophys Res Commun. 2018. PMID: 29522715
In mechanism, we showed that FABP5P3 bond to miR-589-5p which served as a tumor suppressor. MiR-589-5p targeted directly the mRNA of ZMYND19 whose function has not been defined in HCC. FABP5P3 promoted HCC development and progression by sponging miR-589-5p and up-regulatin …
In mechanism, we showed that FABP5P3 bond to miR-589-5p which served as a tumor suppressor. MiR-589-5p targeted directly the mRNA of ZMYN …
The human GID complex engages two independent modules for substrate recruitment.
Mohamed WI, Park SL, Rabl J, Leitner A, Boehringer D, Peter M. Mohamed WI, et al. EMBO Rep. 2021 Nov 4;22(11):e52981. doi: 10.15252/embr.202152981. Epub 2021 Oct 14. EMBO Rep. 2021. PMID: 34647674 Free PMC article.
In contrast, GID4 functions as an adaptor for the substrate ZMYND19, which surprisingly lacks a Pro/N-end degron. GID4 substrate binding and ligase activity is regulated by ARMC8alpha, while the shorter ARMC8beta isoform assembles into a stable hGID complex that is unable …
In contrast, GID4 functions as an adaptor for the substrate ZMYND19, which surprisingly lacks a Pro/N-end degron. GID4 substrate bind …
Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury.
Gáspár R, Gömöri K, Kiss B, Szántai Á, Pálóczi J, Varga ZV, Pipis J, Váradi B, Ágg B, Csont T, Ferdinandy P, Barteková M, Görbe A. Gáspár R, et al. Molecules. 2020 Jul 28;25(15):3426. doi: 10.3390/molecules25153426. Molecules. 2020. PMID: 32731559 Free PMC article.
No one of the inhibitors of survival pathways (L-NAME, KT-5823, TAK-242) influenced the cardiocytoprotective effect of decorin. MYND-type containing 19 (Zmynd19) and eukaryotic translation initiation factor 4E nuclear import factor 1 (Eif4enif1) were significantly upregula …
No one of the inhibitors of survival pathways (L-NAME, KT-5823, TAK-242) influenced the cardiocytoprotective effect of decorin. MYND-type co …
Biomarker Identification through Multiomics Data Analysis of Prostate Cancer Prognostication Using a Deep Learning Model and Similarity Network Fusion.
Wang TH, Lee CY, Lee TY, Huang HD, Hsu JB, Chang TH. Wang TH, et al. Cancers (Basel). 2021 May 21;13(11):2528. doi: 10.3390/cancers13112528. Cancers (Basel). 2021. PMID: 34064004 Free PMC article.
Then, multiomics panels were constructed according to the intersected omics biomarkers identified from the two models. Six intersected omics biomarkers, TELO2, ZMYND19, miR-143, miR-378a, cg00687383 (MED4), and cg02318866 (JMJD6; METTL23), were collected for multiomics pan …
Then, multiomics panels were constructed according to the intersected omics biomarkers identified from the two models. Six intersected omics …