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Peripheral monocytes are functionally altered and invade the CNS in ALS patients.
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, Hengerer B, Gottschalk KE, Hill O, Kluge M, Ludolph AC, Danzer KM, Weishaupt JH. Zondler L, et al. Acta Neuropathol. 2016 Sep;132(3):391-411. doi: 10.1007/s00401-016-1548-y. Epub 2016 Feb 24. Acta Neuropathol. 2016. PMID: 26910103
Inflammatory dysregulation of blood monocytes in Parkinson's disease patients.
Grozdanov V, Bliederhaeuser C, Ruf WP, Roth V, Fundel-Clemens K, Zondler L, Brenner D, Martin-Villalba A, Hengerer B, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. Grozdanov V, et al. Among authors: zondler l. Acta Neuropathol. 2014 Nov;128(5):651-63. doi: 10.1007/s00401-014-1345-4. Epub 2014 Oct 5. Acta Neuropathol. 2014. PMID: 25284487 Free PMC article.
Serum microRNAs in sporadic amyotrophic lateral sclerosis.
Freischmidt A, Müller K, Zondler L, Weydt P, Mayer B, von Arnim CA, Hübers A, Dorst J, Otto M, Holzmann K, Ludolph AC, Danzer KM, Weishaupt JH. Freischmidt A, et al. Among authors: zondler l. Neurobiol Aging. 2015 Sep;36(9):2660.e15-20. doi: 10.1016/j.neurobiolaging.2015.06.003. Epub 2015 Jun 9. Neurobiol Aging. 2015. PMID: 26142125
Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes.
Bliederhaeuser C, Grozdanov V, Speidel A, Zondler L, Ruf WP, Bayer H, Kiechle M, Feiler MS, Freischmidt A, Brenner D, Witting A, Hengerer B, Fändrich M, Ludolph AC, Weishaupt JH, Gillardon F, Danzer KM. Bliederhaeuser C, et al. Among authors: zondler l. Acta Neuropathol. 2016 Mar;131(3):379-91. doi: 10.1007/s00401-015-1504-2. Epub 2015 Nov 17. Acta Neuropathol. 2016. PMID: 26576561
α-synuclein interacts with SOD1 and promotes its oligomerization.
Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. Helferich AM, et al. Among authors: zondler l. Mol Neurodegener. 2015 Dec 8;10:66. doi: 10.1186/s13024-015-0062-3. Mol Neurodegener. 2015. PMID: 26643113 Free PMC article.
Impaired activation of ALS monocytes by exosomes.
Zondler L, Feiler MS, Freischmidt A, Ruf WP, Ludolph AC, Danzer KM, Weishaupt JH. Zondler L, et al. Immunol Cell Biol. 2017 Feb;95(2):207-214. doi: 10.1038/icb.2016.89. Epub 2016 Sep 12. Immunol Cell Biol. 2017. PMID: 27616750
LRRK2 contributes to monocyte dysregulation in Parkinson's disease.
Bliederhaeuser C, Zondler L, Grozdanov V, Ruf WP, Brenner D, Melrose HL, Bauer P, Ludolph AC, Gillardon F, Kassubek J, Weishaupt JH, Danzer KM. Bliederhaeuser C, et al. Among authors: zondler l. Acta Neuropathol Commun. 2016 Nov 24;4(1):123. doi: 10.1186/s40478-016-0396-2. Acta Neuropathol Commun. 2016. PMID: 27884177 Free PMC article. No abstract available.
Age Increases Monocyte Adhesion on Collagen.
Khalaji S, Zondler L, KleinJan F, Nolte U, Mulaw MA, Danzer KM, Weishaupt JH, Gottschalk KE. Khalaji S, et al. Among authors: zondler l. Sci Rep. 2017 May 17;7:46532. doi: 10.1038/srep46532. Sci Rep. 2017. PMID: 28513618 Free PMC article.
Proteasome impairment by α-synuclein.
Zondler L, Kostka M, Garidel P, Heinzelmann U, Hengerer B, Mayer B, Weishaupt JH, Gillardon F, Danzer KM. Zondler L, et al. PLoS One. 2017 Sep 25;12(9):e0184040. doi: 10.1371/journal.pone.0184040. eCollection 2017. PLoS One. 2017. PMID: 28945746 Free PMC article.
19 results