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1993 1
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2005 11
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260 results

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Page 1
Levetiracetam in absence epilepsy.
Verrotti A, Cerminara C, Domizio S, Mohn A, Franzoni E, Coppola G, Zamponi N, Parisi P, Iannetti P, Curatolo P. Verrotti A, et al. Dev Med Child Neurol. 2008 Nov;50(11):850-3. doi: 10.1111/j.1469-8749.2008.03099.x. Epub 2008 Sep 19. Dev Med Child Neurol. 2008. PMID: 18808424 Free article. Clinical Trial.
The aim of the study was to assess the efficacy, tolerability, and safety of levetiracetam therapy in children and adolescents with absence epilepsy. ...Two patients who had shown no improvement at 6 months had decreased seizures at the second follow-up. Our …
The aim of the study was to assess the efficacy, tolerability, and safety of levetiracetam therapy in children and adolescents with …
Epilepsy in Angelman syndrome: A scoping review.
Samanta D. Samanta D. Brain Dev. 2021 Jan;43(1):32-44. doi: 10.1016/j.braindev.2020.08.014. Epub 2020 Sep 4. Brain Dev. 2021. PMID: 32893075 Free PMC article. Review.
Underlying pathophysiology may involve neocortical and thalamocortical hyperexcitability secondary to severe reduction of GABAergic input, as well as dysfunctional synaptic plasticity, deficient synaptogenesis, and neuronal morphological immaturity. The onset of epilepsy i …
Underlying pathophysiology may involve neocortical and thalamocortical hyperexcitability secondary to severe reduction of GABAergic input, a …
Therapeutic Options for Childhood Absence Epilepsy.
Rinaldi VE, Di Cara G, Mencaroni E, Verrotti A. Rinaldi VE, et al. Pediatr Rep. 2021 Dec 16;13(4):658-667. doi: 10.3390/pediatric13040078. Pediatr Rep. 2021. PMID: 34941639 Free PMC article. Review.
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. ...In the case of first line treatment failure, after two monotherapies it is usual to start a bi-therapy. In the case of absence seizures that are refractory to traditiona …
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. ...In the case of first line treatment …
Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.
Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Guerreiro C, Kälviäinen R, Mattson R, French JA, Perucca E, Tomson T; ILAE Subcommission on AED Guidelines. Glauser T, et al. Epilepsia. 2013 Mar;54(3):551-63. doi: 10.1111/epi.12074. Epub 2013 Jan 25. Epilepsia. 2013. PMID: 23350722 Free article. Review.
New efficacy/effectiveness findings include the following: levetiracetam and zonisamide have level A evidence in adults with partial onset seizures and both ethosuximide and valproic acid have level A evidence in children with childhood absence epilepsy. ...A …
New efficacy/effectiveness findings include the following: levetiracetam and zonisamide have level A evidence in adults with partial …
Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis.
Chu H, Zhang X, Shi J, Zhou Z, Yang X. Chu H, et al. J Neurol. 2023 Oct;270(10):4713-4728. doi: 10.1007/s00415-023-11834-8. Epub 2023 Jun 28. J Neurol. 2023. PMID: 37378757 Free PMC article. Review.
Studies on the efficacy and safety of ASM monotherapies or adjunctive therapies for IGEs and related entities-including juvenile myoclonic epilepsy, childhood absence epilepsy (CAE), juvenile absence epilepsy, or generalized tonic-clonic seizure …
Studies on the efficacy and safety of ASM monotherapies or adjunctive therapies for IGEs and related entities-including juvenile myoclonic …
Current advances in childhood absence epilepsy.
Matricardi S, Verrotti A, Chiarelli F, Cerminara C, Curatolo P. Matricardi S, et al. Pediatr Neurol. 2014 Mar;50(3):205-12. doi: 10.1016/j.pediatrneurol.2013.10.009. Epub 2013 Oct 23. Pediatr Neurol. 2014. PMID: 24530152 Review.
BACKGROUND: Childhood absence epilepsy is an age-dependent, idiopathic, generalized epilepsy with a characteristic seizure appearance. The disorder is likely to be multifactorial, resulting from interactions between genetic and acquired factors, but the debat …
BACKGROUND: Childhood absence epilepsy is an age-dependent, idiopathic, generalized epilepsy with a characteristic seiz …
Levetiracetam.
Haria M, Balfour JA. Haria M, et al. CNS Drugs. 1997 Feb;7(2):159-64. doi: 10.2165/00023210-199707020-00006. CNS Drugs. 1997. PMID: 23338133
[Symbol: see text] Levetiracetam is an ethyl analogue of the nootropic agent piracetam.[Symbol: see text] Results from rodent studies indicate that the drug may offer protection against absence, generalised and partial seizures....[Symbol: see text] Initial findings …
[Symbol: see text] Levetiracetam is an ethyl analogue of the nootropic agent piracetam.[Symbol: see text] Results from rodent studies …
Psychiatric and behavioral side effects of antiepileptic drugs in adults with epilepsy.
Chen B, Choi H, Hirsch LJ, Katz A, Legge A, Buchsbaum R, Detyniecki K. Chen B, et al. Epilepsy Behav. 2017 Nov;76:24-31. doi: 10.1016/j.yebeh.2017.08.039. Epub 2017 Sep 18. Epilepsy Behav. 2017. PMID: 28931473 Review.
History of psychiatric condition(s), secondary generalized seizures, absence seizures, and intractable epilepsy were associated with increased incidence of PBSE. Levetiracetam (LEV) had the greatest PBSE rate (22.1%). This was statistically significant when c …
History of psychiatric condition(s), secondary generalized seizures, absence seizures, and intractable epilepsy were associate …
Effects of in utero exposure to valproate or levetiracetam on the seizures and newborn histopathology of genetic absence epilepsy rats.
Can Kantarci B, Sanli A, Gavas S, Toplu A, Nur Turgan Asik Z, Tugce Cilingir-Kaya O, Gulcebi Idrizoglu M, Ercan F, Onat F. Can Kantarci B, et al. Neurosci Lett. 2022 Apr 17;776:136574. doi: 10.1016/j.neulet.2022.136574. Epub 2022 Mar 8. Neurosci Lett. 2022. PMID: 35271996
Valproate (VPA) and levetiracetam (LEV), the two broad spectrum antiseizure drugs with antiabsence effects were previously tested for their antiepileptogenic effects when administered in the early postnatal period and revealed possible modification of the epileptogenic pro …
Valproate (VPA) and levetiracetam (LEV), the two broad spectrum antiseizure drugs with antiabsence effects were previously tested for …
Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new-onset epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society.
Kanner AM, Ashman E, Gloss D, Harden C, Bourgeois B, Bautista JF, Abou-Khalil B, Burakgazi-Dalkilic E, Llanas Park E, Stern J, Hirtz D, Nespeca M, Gidal B, Faught E, French J. Kanner AM, et al. Neurology. 2018 Jul 10;91(2):74-81. doi: 10.1212/WNL.0000000000005755. Epub 2018 Jun 13. Neurology. 2018. PMID: 29898971
RESULTS: Several second-generation AEDs are effective for new-onset focal epilepsy. Data are lacking on efficacy in new-onset generalized tonic-clonic seizures, juvenile myoclonic epilepsy, or juvenile absence epilepsy, and on efficacy of third-generat …
RESULTS: Several second-generation AEDs are effective for new-onset focal epilepsy. Data are lacking on efficacy in new-onset general …
260 results