Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1966 1
1970 1
1971 1
1972 2
1973 1
1975 2
1976 5
1977 1
1978 3
1979 3
1980 5
1981 2
1982 4
1983 5
1984 6
1985 8
1986 10
1987 6
1988 7
1989 12
1990 7
1991 8
1992 9
1993 11
1994 16
1995 14
1996 14
1997 18
1998 30
1999 23
2000 29
2001 38
2002 32
2003 47
2004 45
2005 46
2006 62
2007 56
2008 48
2009 56
2010 57
2011 83
2012 93
2013 56
2014 46
2015 72
2016 47
2017 82
2018 79
2019 102
2020 117
2021 152
2022 125
2023 142
2024 69

Text availability

Article attribute

Article type

Publication date

Search Results

1,844 results

Results by year

Filters applied: . Clear all
Page 1
Targets and Mechanisms of Geminivirus Silencing Suppressor Protein AC2.
Veluthambi K, Sunitha S. Veluthambi K, et al. Front Microbiol. 2021 Apr 9;12:645419. doi: 10.3389/fmicb.2021.645419. eCollection 2021. Front Microbiol. 2021. PMID: 33897657 Free PMC article. Review.
This review discusses what is currently known about the targets and mechanism of the viral suppressor AC2/AL2/transcriptional activator protein (TrAP) and explore the biotechnological applications of AC2....
This review discusses what is currently known about the targets and mechanism of the viral suppressor AC2/AL2/transcriptional activat …
Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling.
Li W, Jiang H, Bai C, Yu S, Pan Y, Wang C, Li H, Li M, Sheng Y, Chu F, Wang J, Chen Y, Li J, Jiang J. Li W, et al. PeerJ. 2022 Sep 28;10:e14086. doi: 10.7717/peerj.14086. eCollection 2022. PeerJ. 2022. PMID: 36193422 Free PMC article.
We discovered that Ac2-26 reduced the Suzuki score and cell death rate, and increased the cell viability after HIRI. ...Finally, we revealed that Ac2-26 pretreatment could significantly inhibit the activation of IL-22/IL22R1/STAT3 signaling. ...
We discovered that Ac2-26 reduced the Suzuki score and cell death rate, and increased the cell viability after HIRI. ...Finally, we r …
Ac2-26 mitigated acute respiratory distress syndrome rats via formyl peptide receptor pathway.
Ju Y, Qiu L, Sun X, Liu H, Gao W. Ju Y, et al. Ann Med. 2021 Dec;53(1):653-661. doi: 10.1080/07853890.2021.1925149. Ann Med. 2021. PMID: 34008449 Free PMC article.
The present study aims to evaluate the effect and mechanism of Ac2-26 in ARDS. METHODS: Thirty-two rats were anaesthetized and randomized into four groups: sham (S), ARDS (A), ARDS/Ac2-26 (AA), and ARDS/Ac2-26/BOC-2 (AAB) groups. ...The protection of Ac2 …
The present study aims to evaluate the effect and mechanism of Ac2-26 in ARDS. METHODS: Thirty-two rats were anaesthetized and random …
Ac2-26 ameliorates lung ischemia-reperfusion injury via the eNOS pathway.
Gong J, Ju YN, Wang XT, Zhu JL, Jin ZH, Gao W. Gong J, et al. Biomed Pharmacother. 2019 Sep;117:109194. doi: 10.1016/j.biopha.2019.109194. Epub 2019 Jul 4. Biomed Pharmacother. 2019. PMID: 31387174 Free article.
This study aimed to determine the effects and mechanism of AnxA1 on LIRI after lung transplantation. METHODS: Thirty-two rats were randomized into sham, saline, Ac2-26 and Ac2-26/L groups. Rats in the saline, Ac2-26 and Ac2-26/L groups underwent left l …
This study aimed to determine the effects and mechanism of AnxA1 on LIRI after lung transplantation. METHODS: Thirty-two rats were randomize …
Ac2-26 alleviates hepatic ischemia-reperfusion injury based on inhibiting the positive feedback loop of HMGB1/TLR4/NF-kappaB/neutrophils.
Bai C, Jiang Z, Jiang H, Yu S, Li M, Chu F, Sheng Y, Li J, Jiang J, Li W. Bai C, et al. Exp Ther Med. 2022 Sep 14;24(5):673. doi: 10.3892/etm.2022.11609. eCollection 2022 Nov. Exp Ther Med. 2022. PMID: 36237600 Free PMC article.
However the effects of Ac2-26 on an HIRI model have not been reported to date. The purpose of the present study was to determine whether Ac2-26 pretreatment could protect hepatocytes against acute HIRI by inhibiting neutrophil infiltration through regulation of the …
However the effects of Ac2-26 on an HIRI model have not been reported to date. The purpose of the present study was to determine whet …
Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle.
Guerrero J, Regedanz E, Lu L, Ruan J, Bisaro DM, Sunter G. Guerrero J, et al. Front Plant Sci. 2020 May 19;11:591. doi: 10.3389/fpls.2020.00591. eCollection 2020. Front Plant Sci. 2020. PMID: 32508858 Free PMC article. Review.
In addition to suppressing host defenses, AC2/C2 play a critical role in regulating expression of the coat protein during the viral life cycle. It is important that the timing of CP expression is regulated to ensure that ssDNA is converted to dsDNA early during an infectio …
In addition to suppressing host defenses, AC2/C2 play a critical role in regulating expression of the coat protein during the viral l …
Annexin A1 protects against cerebral ischemia-reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway.
Xu X, Gao W, Li L, Hao J, Yang B, Wang T, Li L, Bai X, Li F, Ren H, Zhang M, Zhang L, Wang J, Wang D, Zhang J, Jiao L. Xu X, et al. J Neuroinflammation. 2021 May 22;18(1):119. doi: 10.1186/s12974-021-02174-3. J Neuroinflammation. 2021. PMID: 34022892 Free PMC article.
The protection was abrogated when mice received Ac2-26 together with WRW4, which is a specific antagonist of formyl peptide receptor type 2/lipoxin A4 receptor (FPR2/ALX). Furthermore, the interaction between Ac2-26 and FPR2/ALX receptor activated the 5' adenosine m …
The protection was abrogated when mice received Ac2-26 together with WRW4, which is a specific antagonist of formyl peptide receptor …
Annexin-A1-Derived Peptide Ac2-26 Suppresses Allergic Airway Inflammation and Remodelling in Mice.
Ferreira TPT, Guimarães FV, Sá YAPJ, da Silva Ribeiro NB, de Arantes ACS, de Frias Carvalho V, Sousa LP, Perretti M, Martins MA, E Silva PMR. Ferreira TPT, et al. Cells. 2022 Feb 22;11(5):759. doi: 10.3390/cells11050759. Cells. 2022. PMID: 35269381 Free PMC article.
Annexin-A1 (AnxA1) and its N-terminal derived peptide Ac2-26 regulate the inflammatory response in several experimental models of disorders. ...Ac2-26 also inhibited AHR and mediator production. Collectively, our findings show that the AnxA1-derived peptide Ac2 …
Annexin-A1 (AnxA1) and its N-terminal derived peptide Ac2-26 regulate the inflammatory response in several experimental models of dis …
Annexin A1 (Ac2-26)-dependent Fpr2 receptor alleviates sepsis-induced acute kidney injury by inhibiting inflammation and apoptosis in vivo and in vitro.
Zheng Y, Li Y, Li S, Hu R, Zhang L. Zheng Y, et al. Inflamm Res. 2023 Feb;72(2):347-362. doi: 10.1007/s00011-022-01640-9. Epub 2022 Dec 22. Inflamm Res. 2023. PMID: 36544058 Free PMC article.
METHODS: In vivo, SI-AKI mouse models were established via caecal ligation and puncture (CLP) and were then treated with the Ac2-26 peptide of ANXA1 (ANXA1 (Ac2-26)), WRW4 (Fpr2 antagonist) or both. ...CONCLUSIONS: Taken together, this study provides evidence that t …
METHODS: In vivo, SI-AKI mouse models were established via caecal ligation and puncture (CLP) and were then treated with the Ac2-26 p …
Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway.
Gong J, Tai QH, Xu GX, Wang XT, Zhu JL, Zhao XQ, Sun HB, Zhu D, Gao W. Gong J, et al. Mediators Inflamm. 2020 Aug 18;2020:3649613. doi: 10.1155/2020/3649613. eCollection 2020. Mediators Inflamm. 2020. PMID: 32908448 Free PMC article.
METHODS: Sixty-four rats were randomized into sham, saline, Ac2-26, and Ac2-26+L-NIO (endothelial nitric oxide synthase (eNOS) inhibitor) groups. Rats received Ac2-26, Ac2-26+L-NIO, or saline after CPR. Neurologic function was assessed at baseline, 24, …
METHODS: Sixty-four rats were randomized into sham, saline, Ac2-26, and Ac2-26+L-NIO (endothelial nitric oxide synthase (eNOS) …
1,844 results