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Showing results for
acid mefenamic mk
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acido-mefenamico-mk
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Evidence for neuroprotection by the fenamate NSAID, mefenamic acid.
Neurochem Int. 2009 Dec;55(7):683-8. doi: 10.1016/j.neuint.2009.06.014. Epub 2009 Jun 27.
Neurochem Int. 2009.
PMID: 19563851
The aim of this study was to investigate the hypothesis that the fenamate, mefenamic acid, is neuroprotective in an in vitro and in vivo model of stroke. ...Ischemic damage was then assessed 24h after MCAO. In vitro, mefenamic acid (10-100microM) and …
The aim of this study was to investigate the hypothesis that the fenamate, mefenamic acid, is neuroprotective in an in vitro a …
Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions( ).
Kahma H, Filppula AM, Neuvonen M, Tarkiainen EK, Tornio A, Holmberg MT, Itkonen MK, Finel M, Neuvonen PJ, Niemi M, Backman JT.
Kahma H, et al.
Drug Metab Dispos. 2018 Feb;46(2):141-150. doi: 10.1124/dmd.117.078162. Epub 2017 Nov 14.
Drug Metab Dispos. 2018.
PMID: 29138287
The UGT2B17 inhibitor imatinib and the UGT2B7 and UGT1A9 inhibitor mefenamic acid inhibited clopidogrel carboxylic acid glucuronidation in HIMs and HLMs, respectively. Incubation of clopidogrel carboxylic acid in HLMs with UDPGA and NADPH resulted in s …
The UGT2B17 inhibitor imatinib and the UGT2B7 and UGT1A9 inhibitor mefenamic acid inhibited clopidogrel carboxylic acid …
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Physiological role of Ca2+-permeable nonselective cation channel in endothelin-1-induced contraction of rabbit aorta.
Komuro T, Miwa S, Zhang XF, Minowa T, Enoki T, Kobayashi S, Okamoto Y, Ninomiya H, Sawamura T, Kikuta K, Iwamuro Y, Furutani H, Hasegawa H, Uemura Y, Kikuchi H, Masaki T.
Komuro T, et al.
J Cardiovasc Pharmacol. 1997 Oct;30(4):504-9. doi: 10.1097/00005344-199710000-00015.
J Cardiovasc Pharmacol. 1997.
PMID: 9335411
Mefenamic acid (< or =10[-3] M) had little effect on the contraction induced by 45 x 10(-3) M K+ or 1 x 10(-6) M Bay K-8644 in combination with 15 x 10(-3) M K+, indicating that it does not affect voltage-operated calcium channels (VOCs) and contractile mechanism …
Mefenamic acid (< or =10[-3] M) had little effect on the contraction induced by 45 x 10(-3) M K+ or 1 x 10(-6) M Bay K-8644 …
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