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Year Number of Results
1982 2
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2000 7
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2002 11
2003 11
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2005 16
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2007 26
2008 25
2009 30
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Page 1
Synthesis and antioxidant activity of conjugates of hydroxytyrosol and coumarin.
Li WB, Qiao XP, Wang ZX, Wang S, Chen SW. Li WB, et al. Bioorg Chem. 2020 Dec;105:104427. doi: 10.1016/j.bioorg.2020.104427. Epub 2020 Oct 24. Bioorg Chem. 2020. PMID: 33161248
The all target compounds 14a-t exhibited better radical scavenging activity than BHT, hydroxytyrosol, and coumarin in both DPPH radical and ABTS(+) radical cation scavenging assays. The structure-activity relationships study indicated that the number and posi …
The all target compounds 14a-t exhibited better radical scavenging activity than BHT, hydroxytyrosol, and coumarin in both DPP …
Antibacterial Activity of Hydroxytyrosol Acetate from Olive Leaves (Olea Europaea L.).
Wei J, Wang S, Pei D, Qu L, Li Y, Chen J, Di D, Gao K. Wei J, et al. Nat Prod Res. 2018 Aug;32(16):1967-1970. doi: 10.1080/14786419.2017.1356830. Epub 2017 Aug 2. Nat Prod Res. 2018. PMID: 28768425
Bacterial growth inhibition, membrane permeabilisation assessment and DNA interaction assays, as well as agarose gel electrophoresis, were employed to elucidate the antibacterial activity of hydroxytyrosol acetate. Results showed that hydroxytyrosol acetate h …
Bacterial growth inhibition, membrane permeabilisation assessment and DNA interaction assays, as well as agarose gel electrophoresis, were e …
Inhibitory Activity of Hydroxytyrosol against Streptolysin O-Induced Hemolysis.
Sogawa K, Kobayashi M, Suzuki J, Sanda A, Kodera Y, Fukuyama M. Sogawa K, et al. Biocontrol Sci. 2018;23(2):77-80. doi: 10.4265/bio.23.77. Biocontrol Sci. 2018. PMID: 29910212 Free article.
Hydroxytyrosol inhibited SLO-induced hemolytic activity, and the amount required for 50% inhibition of hemolysis was 1.30 g. These findings suggest that the water-soluble polyphenols contained in olives have inhibitory activity against SLO-induced hemolysis.. …
Hydroxytyrosol inhibited SLO-induced hemolytic activity, and the amount required for 50% inhibition of hemolysis was 1.30 g. T …
Antioxidant activity of Hydroxytyrosol and Vitamin E reduces systemic inflammation in children with paediatric NAFLD.
Mosca A, Crudele A, Smeriglio A, Braghini MR, Panera N, Comparcola D, Alterio A, Sartorelli MR, Tozzi G, Raponi M, Trombetta D, Alisi A. Mosca A, et al. Dig Liver Dis. 2021 Sep;53(9):1154-1158. doi: 10.1016/j.dld.2020.09.021. Epub 2020 Oct 13. Dig Liver Dis. 2021. PMID: 33060043 Clinical Trial.
BACKGROUND: The rise in paediatric non-alcoholic fatty liver disease (NAFLD) is particularly alarming. We recently reported that Hydroxytyrosol (HXT) and Vitamin E (VitE) may improve oxidative stress, insulin resistance, and steatosis in children with biopsy-proven NAFLD. …
BACKGROUND: The rise in paediatric non-alcoholic fatty liver disease (NAFLD) is particularly alarming. We recently reported that Hydroxyt …
Hydroxytyrosol: Bioavailability, toxicity, and clinical applications.
Robles-Almazan M, Pulido-Moran M, Moreno-Fernandez J, Ramirez-Tortosa C, Rodriguez-Garcia C, Quiles JL, Ramirez-Tortosa M. Robles-Almazan M, et al. Food Res Int. 2018 Mar;105:654-667. doi: 10.1016/j.foodres.2017.11.053. Epub 2017 Nov 21. Food Res Int. 2018. PMID: 29433260 Review.
The interest in this molecule has led to wide research on its biological activities, its beneficial effects in humans and how to synthetize new molecules from hydroxytyrosol. ...This review also serves to highlight the role of hydroxytyrosol as a nutraceutica …
The interest in this molecule has led to wide research on its biological activities, its beneficial effects in humans and how to synt …
Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity.
Bedoya LM, Beltrán M, Obregón-Calderón P, García-Pérez J, de la Torre HE, González N, Pérez-Olmeda M, Auñón D, Capa L, Gómez-Acebo E, Alcamí J. Bedoya LM, et al. AIDS. 2016 Nov 28;30(18):2767-2776. doi: 10.1097/QAD.0000000000001283. AIDS. 2016. PMID: 27677167 Free PMC article.
OBJECTIVE: To investigate the toxicity and activity against HIV of 5-hydroxytyrosol as a potential microbicide. ...In-vivo toxicity of 5-hydroxytyrosol was very low even at the highest tested doses. CONCLUSION: 5-Hydroxytyrosol displayed a broad anti-H …
OBJECTIVE: To investigate the toxicity and activity against HIV of 5-hydroxytyrosol as a potential microbicide. ...In-vivo tox …
Protective activity of hydroxytyrosol metabolites on erythrocyte oxidative-induced hemolysis.
Paiva-Martins F, Silva A, Almeida V, Carvalheira M, Serra C, Rodrígues-Borges JE, Fernandes J, Belo L, Santos-Silva A. Paiva-Martins F, et al. J Agric Food Chem. 2013 Jul 10;61(27):6636-42. doi: 10.1021/jf4016202. Epub 2013 Jun 28. J Agric Food Chem. 2013. PMID: 23777263
In the presence of AAPH, all compounds showed to protect RBCs from hemolysis in a dose-dependent manner, exccept for the homovanillyl alcohol glucuronide, with the order of activity being at 20 muM hydroxytyrosol > hydroxytyrosol glucuronides = hydroxyt …
In the presence of AAPH, all compounds showed to protect RBCs from hemolysis in a dose-dependent manner, exccept for the homovanillyl alcoho …
Hydroxytyrosol: A natural compound with promising pharmacological activities.
Bertelli M, Kiani AK, Paolacci S, Manara E, Kurti D, Dhuli K, Bushati V, Miertus J, Pangallo D, Baglivo M, Beccari T, Michelini S. Bertelli M, et al. J Biotechnol. 2020 Feb 10;309:29-33. doi: 10.1016/j.jbiotec.2019.12.016. Epub 2019 Dec 26. J Biotechnol. 2020. PMID: 31884046 Review.
Hydroxytyrosol is a phenolic phytochemical with antioxidant properties in vitro. ...Due to all these biological properties, hydroxytyrosol is currently the most actively investigated natural phenol. ...
Hydroxytyrosol is a phenolic phytochemical with antioxidant properties in vitro. ...Due to all these biological properties, hydrox …
Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity.
Parra-Perez AM, Pérez-Jiménez A, Gris-Cárdenas I, Bonel-Pérez GC, Carrasco-Díaz LM, Mokhtari K, García-Salguero L, Lupiáñez JA, Rufino-Palomares EE. Parra-Perez AM, et al. Int J Mol Sci. 2022 Jun 24;23(13):7053. doi: 10.3390/ijms23137053. Int J Mol Sci. 2022. PMID: 35806065 Free PMC article.
Hydroxytyrosol (HT), the main representative of polyphenols of olive oil, has been described as one of the most powerful natural antioxidants, also showing anti-inflammatory, antimicrobial, cardioprotective and anticancer activity in different type of cancers, but h …
Hydroxytyrosol (HT), the main representative of polyphenols of olive oil, has been described as one of the most powerful natural anti …
Antimicrobial activity of hydroxytyrosol: a current controversy.
Medina-Martínez MS, Truchado P, Castro-Ibáñez I, Allende A. Medina-Martínez MS, et al. Biosci Biotechnol Biochem. 2016;80(4):801-10. doi: 10.1080/09168451.2015.1116924. Epub 2015 Dec 18. Biosci Biotechnol Biochem. 2016. PMID: 26679750
This study focus on the main factors that affect the antimicrobial capacity of hydroxytyrosol, including the concentration (200, 400, and 1000 mug/mL), target strains, and the culture media (nutrient-rich and less-rich culture media). ...It was observed that HT concentrati …
This study focus on the main factors that affect the antimicrobial capacity of hydroxytyrosol, including the concentration (200, 400, …
1,069 results