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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1929 1
1935 1
1936 1
1937 2
1945 1
1946 4
1947 3
1948 7
1949 4
1950 1
1952 3
1953 9
1954 8
1955 7
1956 14
1957 15
1958 13
1959 14
1960 15
1961 24
1962 28
1963 44
1964 42
1965 82
1966 65
1967 84
1968 105
1969 100
1970 104
1971 189
1972 340
1973 339
1974 367
1975 460
1976 472
1977 478
1978 552
1979 608
1980 602
1981 743
1982 756
1983 828
1984 940
1985 876
1986 922
1987 895
1988 830
1989 799
1990 977
1991 865
1992 981
1993 969
1994 998
1995 1051
1996 1074
1997 965
1998 1050
1999 1076
2000 1246
2001 1312
2002 1361
2003 1331
2004 1496
2005 1579
2006 1666
2007 1725
2008 1782
2009 1754
2010 1910
2011 2042
2012 2050
2013 2149
2014 2167
2015 2087
2016 2180
2017 2171
2018 2242
2019 2262
2020 2467
2021 2421
2022 2396
2023 2216
2024 856

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64,737 results

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Page 1
Peroxisomal acyl-CoA synthetases.
Watkins PA, Ellis JM. Watkins PA, et al. Biochim Biophys Acta. 2012 Sep;1822(9):1411-20. doi: 10.1016/j.bbadis.2012.02.010. Epub 2012 Feb 17. Biochim Biophys Acta. 2012. PMID: 22366061 Free PMC article. Review.
Peroxisomes carry out many essential lipid metabolic functions. Nearly all of these functions require that an acyl group-either a fatty acid or the acyl side chain of a steroid derivative-be thioesterified to coenzyme A (CoA) for subsequent reactions to proceed. ... …
Peroxisomes carry out many essential lipid metabolic functions. Nearly all of these functions require that an acyl group-either a fat …
Acyl glucuronide metabolites: Implications for drug safety assessment.
Van Vleet TR, Liu H, Lee A, Blomme EAG. Van Vleet TR, et al. Toxicol Lett. 2017 Apr 15;272:1-7. doi: 10.1016/j.toxlet.2017.03.003. Epub 2017 Mar 7. Toxicol Lett. 2017. PMID: 28286018 Review.
While there is circumstantial evidence that drugs forming acyl glucuronide metabolites can be associated with rare, but severe idiosyncratic toxic reactions, many widely prescribed drugs with good safety records are also metabolized through acyl glucuronidation. The …
While there is circumstantial evidence that drugs forming acyl glucuronide metabolites can be associated with rare, but severe idiosy …
Acyl-coenzyme A:(holo-acyl carrier protein) transacylase enzymes as templates for engineering.
Marcella AM, Barb AW. Marcella AM, et al. Appl Microbiol Biotechnol. 2018 Aug;102(15):6333-6341. doi: 10.1007/s00253-018-9114-2. Epub 2018 Jun 1. Appl Microbiol Biotechnol. 2018. PMID: 29858956 Review.
Furthermore, this review will focus on in vitro characteristics and not cover engineering of the upstream or downstream reactions or strategies to manipulate metabolic flux in vivo. The malonyl-coenzyme A(CoA)-holo-acyl-carrier protein (holo-ACP) transacylase (FabD) from E …
Furthermore, this review will focus on in vitro characteristics and not cover engineering of the upstream or downstream reactions or strateg …
Physiological Consequences of Compartmentalized Acyl-CoA Metabolism.
Cooper DE, Young PA, Klett EL, Coleman RA. Cooper DE, et al. J Biol Chem. 2015 Aug 14;290(33):20023-31. doi: 10.1074/jbc.R115.663260. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124277 Free PMC article. Review.
Indirect evidence suggests that acyl-CoAs do not wander freely within cells, but instead, are channeled into specific pathways. In this review, we will discuss the evidence for acyl-CoA compartmentalization, highlight the key modes of acyl-CoA regulation, and …
Indirect evidence suggests that acyl-CoAs do not wander freely within cells, but instead, are channeled into specific pathways. In th …
Are there acyl-homoserine lactones within mammalian intestines?
Swearingen MC, Sabag-Daigle A, Ahmer BM. Swearingen MC, et al. J Bacteriol. 2013 Jan;195(2):173-9. doi: 10.1128/JB.01341-12. Epub 2012 Nov 9. J Bacteriol. 2013. PMID: 23144246 Free PMC article. Review.
Many Proteobacteria are capable of quorum sensing using N-acyl-homoserine lactone (acyl-HSL) signaling molecules that are synthesized by LuxI or LuxM homologs and detected by transcription factors of the LuxR family. ...However, there is currently no evidence of …
Many Proteobacteria are capable of quorum sensing using N-acyl-homoserine lactone (acyl-HSL) signaling molecules that are synt …
Ischemia promotes acyl-CoAs dephosphorylation and propionyl-CoA accumulation.
He W, Berthiaume JM, Previs S, Kasumov T, Zhang GF. He W, et al. Metabolomics. 2023 Feb 7;19(2):12. doi: 10.1007/s11306-023-01975-2. Metabolomics. 2023. PMID: 36750484
OBJECTIVES: To understand the relationship between acyl-CoAs dephosphorylation and energy status as implied in our previous work, we seek to investigate how ischemia (energy depletion) triggers metabolic changes, specifically acyl-CoAs dephosphorylation in this work …
OBJECTIVES: To understand the relationship between acyl-CoAs dephosphorylation and energy status as implied in our previous work, we …
Acyl-CoA-binding protein (ACBP) and its relation to fatty acid-binding protein (FABP): an overview.
Knudsen J. Knudsen J. Mol Cell Biochem. 1990 Oct 15-Nov 8;98(1-2):217-23. doi: 10.1007/BF00231387. Mol Cell Biochem. 1990. PMID: 2266962 Review.
Acyl-CoA-binding protein is a 10 Kd protein which binds medium- and long-chain acyl-CoA esters with high affinity. The concentration in liver is 2-4 times the acyl-CoA concentration. ACBP has much greater affinity for acyl-CoA than FABP. ...
Acyl-CoA-binding protein is a 10 Kd protein which binds medium- and long-chain acyl-CoA esters with high affinity. The concent …
The acyl carrier protein dance.
Zamberlan F. Zamberlan F. Nat Chem Biol. 2024 Jan;20(1):3. doi: 10.1038/s41589-023-01517-w. Nat Chem Biol. 2024. PMID: 38102405 No abstract available.
Long-chain acyl-CoA hydrolase in the brain.
Yamada J. Yamada J. Amino Acids. 2005 May;28(3):273-8. doi: 10.1007/s00726-005-0181-1. Epub 2005 Mar 2. Amino Acids. 2005. PMID: 15731883 Review.
Long-chain acyl-CoA hydrolases are a group of enzymes that cleave acyl-CoAs into fatty acids and coenzyme A (CoA-SH). ...Therefore, acyl-CoA synthetases have been intensively studied. In contrast, acyl-CoA hydrolases have been less investigated, especi …
Long-chain acyl-CoA hydrolases are a group of enzymes that cleave acyl-CoAs into fatty acids and coenzyme A (CoA-SH). ...There …
Drug-S-acyl-glutathione thioesters: synthesis, bioanalytical properties, chemical reactivity, biological formation and degradation.
Grillo MP. Grillo MP. Curr Drug Metab. 2011 Mar;12(3):229-44. doi: 10.2174/138920011795101886. Curr Drug Metab. 2011. PMID: 20946099 Review.
Chemical reactivity comparisons have shown that S-acyl-CoA thioester and acyl-adenylate conjugates are more reactive than their corresponding 1-beta-O-acyl glucuronides toward the transacylation of GSH forming S-acyl-GSH thioesters. ...Glutathione S-tr …
Chemical reactivity comparisons have shown that S-acyl-CoA thioester and acyl-adenylate conjugates are more reactive than thei …
64,737 results
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