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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 5
1962 6
1963 6
1964 2
1965 6
1966 4
1967 8
1968 9
1969 12
1970 21
1971 10
1972 38
1973 57
1974 62
1975 69
1976 66
1977 72
1978 48
1979 57
1980 35
1981 42
1982 56
1983 55
1984 56
1985 61
1986 46
1987 63
1988 63
1989 51
1990 58
1991 52
1992 44
1993 42
1994 48
1995 54
1996 30
1997 39
1998 43
1999 43
2000 65
2001 43
2002 45
2003 53
2004 55
2005 65
2006 77
2007 65
2008 68
2009 58
2010 54
2011 68
2012 55
2013 82
2014 104
2015 55
2016 59
2017 58
2018 68
2019 61
2020 58
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2022 66
2023 50
2024 25

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Did you mean aspect (731,718 results)?
Spectinomycin.
Holloway WJ. Holloway WJ. Med Clin North Am. 1982 Jan;66(1):169-73. Med Clin North Am. 1982. PMID: 6460907 Review.
Spectinomycin is a broad-spectrum aminocyclitol antibiotic that is highly effective in the treatment of uncomplicated gonorrhea. ...Spectinomycin is not predictably effective in the treatment of oral pharyngeal gonorrhea but may be used in penicillin-allergic patien …
Spectinomycin is a broad-spectrum aminocyclitol antibiotic that is highly effective in the treatment of uncomplicated gonorrhea. ... …
Gonococcal keratoconjunctivitis.
Ullman S, Roussel TJ, Forster RK. Ullman S, et al. Surv Ophthalmol. 1987 Nov-Dec;32(3):199-208. doi: 10.1016/0039-6257(87)90095-6. Surv Ophthalmol. 1987. PMID: 2965423 Free article. Review.
The third generation cephalosporin, ceftriaxone, has properties that suggest it may be the best available antimicrobial agent as a single-dose treatment of gonococcal conjunctivitis. Spectinomycin may be a useful alternative in the penicillin-allergic adult patient....
The third generation cephalosporin, ceftriaxone, has properties that suggest it may be the best available antimicrobial agent as a single-do …
Aminocyclitol.
Cargill JS. Cargill JS. Lancet. 1977 Jan 29;1(8005):260. doi: 10.1016/s0140-6736(77)91062-5. Lancet. 1977. PMID: 64791 No abstract available.
Synthesis of 4-amino-4(S)-dihydrospectinomycin.
Hanessian S, Roy R, Therien M, Delorme D. Hanessian S, et al. J Antibiot (Tokyo). 1981 Mar;34(3):350-2. doi: 10.7164/antibiotics.34.350. J Antibiot (Tokyo). 1981. PMID: 6456250 Free article. No abstract available.
Drugs five years later. Spectinomycin.
McCormack WM, Finland M. McCormack WM, et al. Ann Intern Med. 1976 Jun;84(6):712-6. doi: 10.7326/0003-4819-84-6-712. Ann Intern Med. 1976. PMID: 132888 Review.
A single dose of spectinomycin does not appear to be reliably effective in the treatment of gonococcal pharyngitis. ...In the dosage used for gonococcal infections, spectinomycin has little effect on infection with Treponema pallidum. ...
A single dose of spectinomycin does not appear to be reliably effective in the treatment of gonococcal pharyngitis. ...In the dosage …
Fed-batch bioproduction of spectinomycin.
Gomes J, Menawat AS. Gomes J, et al. Adv Biochem Eng Biotechnol. 1998;59:1-46. doi: 10.1007/BFb0102295. Adv Biochem Eng Biotechnol. 1998. PMID: 9435459 Review.
A nonlinear systems theory technique termed External Differential Representation, is implemented to reconstruct the spectinomycin bioconversion process which then predicts the spectinomycin concentration from the air flow rate profile. This signifies that spectin …
A nonlinear systems theory technique termed External Differential Representation, is implemented to reconstruct the spectinomycin bio …
Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins.
Dharuman S, Wilt LA, Liu J, Reeve SM, Thompson CW, Elmore JM, Shcherbakov D, Lee RB, Böttger EC, Lee RE. Dharuman S, et al. J Antibiot (Tokyo). 2021 Jun;74(6):381-396. doi: 10.1038/s41429-021-00408-3. Epub 2021 Jan 27. J Antibiot (Tokyo). 2021. PMID: 33504919 Free PMC article.
Spectinomycin, an aminocyclitol antibiotic, is subject to inactivation by aminoglycoside modifying enzymes (AMEs) through adenylylation or phosphorylation of the 6-hydroxy group position. In this study, the effects of deoxygenation of the 2- and 6-hydroxy group positions o …
Spectinomycin, an aminocyclitol antibiotic, is subject to inactivation by aminoglycoside modifying enzymes (AMEs) through adenylylati …
Spectinomycin in gonorrhoea.
Ribeiro J, Mathieson SI. Ribeiro J, et al. Br J Vener Dis. 1975 Aug;51(4):272-3. doi: 10.1136/sti.51.4.272. Br J Vener Dis. 1975. PMID: 125619 Free PMC article. Clinical Trial.
Of 104 male and nine female patients with uncomplicated acute gonorrhoea who were treated with spectinomycin (males 2 g., females 4 g.), two patients (one male and one female) were considered to be treatment failures. ...Sensitivity tests were carried out on 44 strains of …
Of 104 male and nine female patients with uncomplicated acute gonorrhoea who were treated with spectinomycin (males 2 g., females 4 g …
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis.
Gonzalez-Juarrero M, Lukka PB, Wagh S, Walz A, Arab J, Pearce C, Ali Z, Ryman JT, Parmar K, Temrikar Z, Munoz-Gutierrez J, Robertson GT, Liu J, Lenaerts AJ, Daley C, Lee RE, Braunstein M, Hickey AJ, Meibohm B. Gonzalez-Juarrero M, et al. ACS Infect Dis. 2021 Oct 8;7(10):2850-2863. doi: 10.1021/acsinfecdis.1c00213. Epub 2021 Sep 21. ACS Infect Dis. 2021. PMID: 34546724 Free PMC article.
One approach to improve TB therapy is to develop an inhalational TB therapy that when administered in combination with oral TB drugs eases and shortens treatment. Spectinamides are new semisynthetic analogues of spectinomycin with excellent activity against Mycobacterium t …
One approach to improve TB therapy is to develop an inhalational TB therapy that when administered in combination with oral TB drugs eases a …
Spectinomycin-resistant Neisseria gonorrhoeae--worldwide.
Centers for Disease Control (CDC). Centers for Disease Control (CDC). MMWR Morb Mortal Wkly Rep. 1982 Dec 3;31(47):632, 637-8. MMWR Morb Mortal Wkly Rep. 1982. PMID: 6218390 Free article. No abstract available.
2,910 results