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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1990 1
1991 2
1992 5
1994 7
1995 10
1996 13
1997 13
1998 9
1999 15
2000 16
2001 12
2002 7
2003 15
2004 21
2005 19
2006 29
2007 24
2008 28
2009 26
2010 47
2011 52
2012 59
2013 60
2014 52
2015 37
2016 52
2017 52
2018 43
2019 47
2020 45
2021 26
2022 45
2023 32
2024 18

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843 results

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Page 1
The CD6/ALCAM pathway promotes lupus nephritis via T cell-mediated responses.
Chalmers SA, Ayilam Ramachandran R, Garcia SJ, Der E, Herlitz L, Ampudia J, Chu D, Jordan N, Zhang T, Parodis I, Gunnarsson I, Ding H, Shen N, Petri M, Mok CC, Saxena R, Polu KR, Connelly S, Ng CT, Mohan C, Putterman C. Chalmers SA, et al. J Clin Invest. 2022 Jan 4;132(1):e147334. doi: 10.1172/JCI147334. J Clin Invest. 2022. PMID: 34981775 Free PMC article.
T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM), are involved in T cell activation …
T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE). CD6 and its li …
ALCAM/CD166: A pleiotropic mediator of cell adhesion, stemness and cancer progression.
Ferragut F, Vachetta VS, Troncoso MF, Rabinovich GA, Elola MT. Ferragut F, et al. Cytokine Growth Factor Rev. 2021 Oct;61:27-37. doi: 10.1016/j.cytogfr.2021.07.001. Epub 2021 Jul 9. Cytokine Growth Factor Rev. 2021. PMID: 34272152 Review.
Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein involved in homotypic and heterotypic cell adhesion. ...Finally, we highlight the role of ALCAM as a cancer stem cell marker and introd
Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein involved in homotypic a
ALCAM/CD166: cancer-related issues.
Weidle UH, Eggle D, Klostermann S, Swart GW. Weidle UH, et al. Cancer Genomics Proteomics. 2010 Sep-Oct;7(5):231-43. Cancer Genomics Proteomics. 2010. PMID: 20952758 Review.
Activated leucocyte adhesion molecule (ALCAM) was originally identified as a transmembrane receptor which is involved in T-cell activation and has other still unresolved functions in hematopoiesis, development, inflammation and transendothelial migrati …
Activated leucocyte adhesion molecule (ALCAM) was originally identified as a transmembrane receptor which is involved i …
ALCAM Makes It All Calm by Inhibiting Apoptosis.
Chen P, Parimon T. Chen P, et al. Am J Respir Cell Mol Biol. 2022 Apr;66(4):356-357. doi: 10.1165/rcmb.2021-0506ED. Am J Respir Cell Mol Biol. 2022. PMID: 35143367 Free PMC article. No abstract available.
ALCAM-EGFR interaction regulates myelomagenesis.
Luo H, Zhang D, Wang F, Wang Q, Wu Y, Gou M, Hu Y, Zhang W, Huang J, Gong Y, Pan L, Li T, Zhao P, Zhang D, Qu Y, Liu Z, Jiang T, Dai Y, Guo T, Zhu J, Ye L, Zhang L, Liu W, Yi Q, Zheng Y. Luo H, et al. Blood Adv. 2021 Dec 14;5(23):5269-5282. doi: 10.1182/bloodadvances.2021004695. Blood Adv. 2021. PMID: 34592762 Free PMC article.
In this study, we discovered that the activated leukocyte cell adhesion molecule (ALCAM) interacted with epidermal growth factor receptor (EGFR), and regulated myelomagenesis. ...BMSCs supported myeloma colony formation by secreted epider …
In this study, we discovered that the activated leukocyte cell adhesion molecule (ALCAM) interacte …
ALCAM regulates multiple myeloma chemoresistant side population.
Wang F, Dan Z, Luo H, Huang J, Cui Y, Ding H, Xu J, Lin Z, Gao Y, Zhai X, Yang Y, Qu Y, Zhang L, Chen F, Wang Q, Wang X, Feng Y, Liu T, Yi Q, Niu T, Zheng Y. Wang F, et al. Cell Death Dis. 2022 Feb 10;13(2):136. doi: 10.1038/s41419-022-04556-8. Cell Death Dis. 2022. PMID: 35145058 Free PMC article.
Drug-resistance is a major problem preventing a cure in patients with multiple myeloma (MM). Previously, we demonstrated that activated-leukocyte-cell-adhesion-molecule (ALCAM) is a prognostic factor in MM and inhibits EGF/EGFR-initiated …
Drug-resistance is a major problem preventing a cure in patients with multiple myeloma (MM). Previously, we demonstrated that activated
Increase of ALCAM and VCAM-1 in the plasma predicts the Alzheimer's disease.
Chen J, Dai AX, Tang HL, Lu CH, Liu HX, Hou T, Lu ZJ, Kong N, Peng XY, Lin KX, Zheng ZD, Xu SL, Ying XF, Ji XY, Pan H, Wu J, Zeng X, Wei NL. Chen J, et al. Front Immunol. 2023 Jan 4;13:1097409. doi: 10.3389/fimmu.2022.1097409. eCollection 2022. Front Immunol. 2023. PMID: 36685605 Free PMC article.
Cell adhesion molecules (CAM) are crucial in several pathological inflammation processes in Alzheimer's disease (AD). ...ALCAM and VCAM-1 combination improved the predictive accuracy significantly. ...
Cell adhesion molecules (CAM) are crucial in several pathological inflammation processes in Alzheimer's disease (AD). ...AL
ALCAM on human oligodendrocytes mediates CD4 T cell adhesion.
Jamann H, Desu HL, Cui QL, Halaweh A, Tastet O, Klement W, Zandee S, Pernin F, Mamane VH, Ouédraogo O, Daigneault A, Sidibé H, Millette F, Peelen E, Dhaeze T, Hoornaert C, Rébillard RM, Thai K, Grasmuck C, Vande Velde C, Prat A, Arbour N, Stratton JA, Antel J, Larochelle C. Jamann H, et al. Brain. 2024 Jan 4;147(1):147-162. doi: 10.1093/brain/awad286. Brain. 2024. PMID: 37640028
We found that a significant proportion of human and murine mature oligodendrocytes express melanoma cell adhesion molecule (MCAM) and activated leukocyte cell adhesion molecule (ALCAM) in multiple sclerosis, in experi …
We found that a significant proportion of human and murine mature oligodendrocytes express melanoma cell adhesion molecule
ALCAM: A Novel Surface Marker on EpCAM(low) Circulating Tumor Cells.
Signorelli R, Giret TM, Umland O, Hadisurya M, Lavania S, Charles Richard JL, Middleton A, Boone MM, Ergonul AB, Tao WA, Amirian H, Iliuk A, Khan A, Diaz R, Cortes DB, Garcia-Buitrago M, Charles Jacob HK. Signorelli R, et al. Biomedicines. 2022 Aug 16;10(8):1983. doi: 10.3390/biomedicines10081983. Biomedicines. 2022. PMID: 36009530 Free PMC article.
Background: Current strategies in circulating tumor cell (CTC) isolation in pancreatic cancer heavily rely on the EpCAM and cytokeratin cell status. ...Results: Surface proteomic profiling of CTCs identified several novel protein biomarkers. ALCAM was identif …
Background: Current strategies in circulating tumor cell (CTC) isolation in pancreatic cancer heavily rely on the EpCAM and cytokerat …
Modulation of cell adhesion and migration through regulation of the immunoglobulin superfamily member ALCAM/CD166.
von Lersner A, Droesen L, Zijlstra A. von Lersner A, et al. Clin Exp Metastasis. 2019 Apr;36(2):87-95. doi: 10.1007/s10585-019-09957-2. Epub 2019 Feb 18. Clin Exp Metastasis. 2019. PMID: 30778704 Free PMC article. Review.
In epithelial-derived cancers, altered regulation of cell-cell adhesion facilitates the disruption of tissue cohesion that is central to the progression to malignant disease. Although numerous intercellular adhesion molecules participate in epithelial …
In epithelial-derived cancers, altered regulation of cell-cell adhesion facilitates the disruption of tissue cohesion t …
843 results