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5-aminolevulinic acid-mediated plant adaptive responses to abiotic stress.
Rhaman MS, Imran S, Karim MM, Chakrobortty J, Mahamud MA, Sarker P, Tahjib-Ul-Arif M, Robin AHK, Ye W, Murata Y, Hasanuzzaman M. Rhaman MS, et al. Plant Cell Rep. 2021 Aug;40(8):1451-1469. doi: 10.1007/s00299-021-02690-9. Epub 2021 Apr 10. Plant Cell Rep. 2021. PMID: 33839877 Review.
5-aminolevulinic acid (ALA) modulates various defense systems in plants and confers abiotic stress tolerance. ...Exogenous application of different plant growth regulators is a well-renowned approach to ameliorate adverse effects of abiotic stresses on crop plants. …
5-aminolevulinic acid (ALA) modulates various defense systems in plants and confers abiotic stress tolerance. ...Exogenous app …
Advances in 5-Aminolevulinic Acid Priming to Enhance Plant Tolerance to Abiotic Stress.
Tan S, Cao J, Xia X, Li Z. Tan S, et al. Int J Mol Sci. 2022 Jan 9;23(2):702. doi: 10.3390/ijms23020702. Int J Mol Sci. 2022. PMID: 35054887 Free PMC article. Review.
Stimuli from chemicals, abiotic cues, and pathogens can trigger the establishment of priming state. Priming with 5-aminolevulinic acid (ALA), a potential plant growth regulator, can enhance plant tolerance to the subsequent abiotic stresses, including salinity, drou …
Stimuli from chemicals, abiotic cues, and pathogens can trigger the establishment of priming state. Priming with 5-aminolevulinic …
5-aminolevulinic acid photodynamic therapy: where we have been and where we are going.
Gold MH, Goldman MP. Gold MH, et al. Dermatol Surg. 2004 Aug;30(8):1077-83; discussion 1083-4. doi: 10.1111/j.1524-4725.2004.30331.x. Dermatol Surg. 2004. PMID: 15274696 Review.
BACKGROUND: Photodynamic therapy, utilizing the topical administration of 20% 5-aminolevulinic acid, has generated a great deal of interest in the dermatology community over the past several years. ...METHODS: A literature review and results of new clinical trials w …
BACKGROUND: Photodynamic therapy, utilizing the topical administration of 20% 5-aminolevulinic acid, has generated a great dea …
On the Possibility of Using 5-Aminolevulinic Acid in the Light-Induced Destruction of Microorganisms.
Zdubek A, Maliszewska I. Zdubek A, et al. Int J Mol Sci. 2024 Mar 22;25(7):3590. doi: 10.3390/ijms25073590. Int J Mol Sci. 2024. PMID: 38612403 Free PMC article. Review.
Antimicrobial photodynamic inactivation (aPDI) is a method that specifically kills target cells by combining a photosensitizer and irradiation with light at the appropriate wavelength. The natural amino acid, 5-aminolevulinic acid (5-ALA), is the precursor of …
Antimicrobial photodynamic inactivation (aPDI) is a method that specifically kills target cells by combining a photosensitizer and irradiati …
Effect of 5-aminolevulinic Acid on Mitochondrial Activity.
Markina YV, Markin AM, Kirichenko TV, Tolstik TV, Cherednichenko VR, Kiseleva DG, Orekhov AN. Markina YV, et al. Front Biosci (Schol Ed). 2023 Dec 27;15(4):17. doi: 10.31083/j.fbs1504017. Front Biosci (Schol Ed). 2023. PMID: 38163956 Free article.
Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5-aminolevulinic acid. This study aimed to investigate the activity of mitochondria in cells with different mutation loads. MATERIALS AND METH …
Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5-aminolevuli …
Chemical approaches for the enhancement of 5-aminolevulinic acid-based photodynamic therapy and photodiagnosis.
Tewari KM, Eggleston IM. Tewari KM, et al. Photochem Photobiol Sci. 2018 Nov 1;17(11):1553-1572. doi: 10.1039/c8pp00362a. Epub 2018 Oct 17. Photochem Photobiol Sci. 2018. PMID: 30328459 Review.
The administration of 5-aminolevulinic acid (ALA) to generate enhanced intracellular levels of endogenous porphyrins is currently one of the most important approaches for photodynamic therapy (PDT) and photodiagnosis (PDD). ...
The administration of 5-aminolevulinic acid (ALA) to generate enhanced intracellular levels of endogenous porphyrins is curren …
Reactive Oxygen Species Produced by 5-Aminolevulinic Acid Photodynamic Therapy in the Treatment of Cancer.
Pignatelli P, Umme S, D'Antonio DL, Piattelli A, Curia MC. Pignatelli P, et al. Int J Mol Sci. 2023 May 18;24(10):8964. doi: 10.3390/ijms24108964. Int J Mol Sci. 2023. PMID: 37240309 Free PMC article. Review.
Added to this is the ancient hypothesis that light alone can be used to kill cancer cells. 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) is a therapeutic option for a variety of cutaneous and internal malignancies. ...
Added to this is the ancient hypothesis that light alone can be used to kill cancer cells. 5-aminolevulinic acid-photodynamic …
Topical aminolevulinic acid HCl photodynamic therapy.
Ormrod D, Jarvis B. Ormrod D, et al. Am J Clin Dermatol. 2000 Mar-Apr;1(2):133-9; discussion 140-1. doi: 10.2165/00128071-200001020-00009. Am J Clin Dermatol. 2000. PMID: 11702313 Review.
Photodynamic therapy (PDT) is the treatment of tumors or dysplasic tissue with drugs that produce cytotoxic metabolites when exposed to light. Aminolevulinic acid HCl (5-aminolevulinic acid HCl; ALA) is a prodrug that is metabolized intracellularly to …
Photodynamic therapy (PDT) is the treatment of tumors or dysplasic tissue with drugs that produce cytotoxic metabolites when exposed to ligh …
Microbial production and applications of 5-aminolevulinic acid.
Liu S, Zhang G, Li X, Zhang J. Liu S, et al. Appl Microbiol Biotechnol. 2014 Sep;98(17):7349-57. doi: 10.1007/s00253-014-5925-y. Epub 2014 Jul 13. Appl Microbiol Biotechnol. 2014. PMID: 25022665 Review.
5-Aminolevulinic acid (ALA), an important intermediate in tetrapyrrole biosynthesis in organisms, has been widely applied in many fields, such as medicine, agriculture, and the food industry, due to its biochemical characteristics. ...
5-Aminolevulinic acid (ALA), an important intermediate in tetrapyrrole biosynthesis in organisms, has been widely applied in m …
5-aminolevulinic acid-photodynamic therapy ameliorates cutaneous granuloma by killing drug-resistant Mycobacterium marinum.
Yang Z, Feng Y, Li D, Pang Z, Wang S, Chen H, Jiang M, Yan H, Li T, Fu H, Xiong H, Shi D. Yang Z, et al. Photodiagnosis Photodyn Ther. 2022 Jun;38:102839. doi: 10.1016/j.pdpdt.2022.102839. Epub 2022 Mar 31. Photodiagnosis Photodyn Ther. 2022. PMID: 35367615
BACKGROUND: Although 5-aminolevulinic acid photodynamic therapy (ALA-PDT) has been extensively used to treat various skin diseases, application for the treatment of cutaneous infection caused by Mycobacterium marinum (M. marinum), especially drug-resistant M. marinu …
BACKGROUND: Although 5-aminolevulinic acid photodynamic therapy (ALA-PDT) has been extensively used to treat various skin dise …
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