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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1966 2
1967 1
1968 1
1969 2
1971 2
1973 1
1974 2
1975 2
1976 4
1977 1
1978 1
1979 2
1980 7
1981 3
1982 7
1983 11
1984 13
1985 17
1986 47
1987 76
1988 135
1989 245
1990 244
1991 331
1992 466
1993 568
1994 669
1995 656
1996 802
1997 802
1998 853
1999 869
2000 1105
2001 1167
2002 1332
2003 1421
2004 1710
2005 1852
2006 2079
2007 2020
2008 2355
2009 2638
2010 3066
2011 3231
2012 3576
2013 3735
2014 3754
2015 3841
2016 3974
2017 4238
2018 4422
2019 4624
2020 5182
2021 5221
2022 5173
2023 5337
2024 2340
2025 2

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77,389 results

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Page 1
beta-Amyloid aggregation and heterogeneous nucleation.
Srivastava AK, Pittman JM, Zerweck J, Venkata BS, Moore PC, Sachleben JR, Meredith SC. Srivastava AK, et al. Protein Sci. 2019 Sep;28(9):1567-1581. doi: 10.1002/pro.3674. Epub 2019 Aug 6. Protein Sci. 2019. PMID: 31276610 Free PMC article. Review.
In this article, we consider the role of heterogeneous nucleation in beta-amyloid aggregation. Heterogeneous nucleation is more common and occurs at lower levels of supersaturation than homogeneous nucleation. ...These two broad classes of nucleators affect beta
In this article, we consider the role of heterogeneous nucleation in beta-amyloid aggregation. Heterogeneous nucleation is mor …
Towards an understanding of amyloid-beta oligomers: characterization, toxicity mechanisms, and inhibitors.
Lee SJ, Nam E, Lee HJ, Savelieff MG, Lim MH. Lee SJ, et al. Chem Soc Rev. 2017 Jan 23;46(2):310-323. doi: 10.1039/c6cs00731g. Chem Soc Rev. 2017. PMID: 27878186 Review.
Alzheimer's disease (AD) is characterized by an imbalance between production and clearance of amyloid-beta (Abeta) species. Abeta peptides can transform structurally from monomers into beta-stranded fibrils via multiple oligomeric states. ...Based on the coll …
Alzheimer's disease (AD) is characterized by an imbalance between production and clearance of amyloid-beta (Abeta) species. Ab …
The role of amyloid-beta in the regulation of memory.
Morley JE, Farr SA. Morley JE, et al. Biochem Pharmacol. 2014 Apr 15;88(4):479-85. doi: 10.1016/j.bcp.2013.12.018. Epub 2014 Jan 4. Biochem Pharmacol. 2014. PMID: 24398426 Review.
In this review there is evidence that amyloid-beta peptide is a memory enhancer at physiological (picomolar) concentrations. ...Antisenses to amyloid precursor protein (APP) can reverse these effects in mice when they lower amyloid-beta protein …
In this review there is evidence that amyloid-beta peptide is a memory enhancer at physiological (picomolar) concentrations. . …
Biological and methodological complexities of beta-amyloid peptide: Implications for Alzheimer's disease research.
Matuszyk MM, Garwood CJ, Ferraiuolo L, Simpson JE, Staniforth RA, Wharton SB. Matuszyk MM, et al. J Neurochem. 2022 Feb;160(4):434-453. doi: 10.1111/jnc.15538. Epub 2021 Nov 24. J Neurochem. 2022. PMID: 34767256 Free article. Review.
Although controversial, the amyloid cascade hypothesis remains central to the Alzheimer's disease (AD) field and posits amyloid-beta (Abeta) as the central factor initiating disease onset. ...
Although controversial, the amyloid cascade hypothesis remains central to the Alzheimer's disease (AD) field and posits amyloid
Amyloid-beta junkies.
Perry G, Nunomura A, Raina AK, Smith MA. Perry G, et al. Lancet. 2000 Feb 26;355(9205):757. doi: 10.1016/S0140-6736(05)72173-5. Lancet. 2000. PMID: 10703837 No abstract available.
Impact of a discordant helix on beta-amyloid structure, aggregation ability and toxicity.
Chen YC. Chen YC. Eur Biophys J. 2017 Oct;46(7):681-687. doi: 10.1007/s00249-017-1235-5. Epub 2017 Jul 7. Eur Biophys J. 2017. PMID: 28687859 Review.
According to amyloid cascade hypothesis, the deposit of amyloid-beta (Abeta) peptide is the main cause of Alzheimer's disease (AD). ...A discordant helix is a helical segment with a tendency to form a beta-strand conformation and has been found in many …
According to amyloid cascade hypothesis, the deposit of amyloid-beta (Abeta) peptide is the main cause of Alzheimer's d …
The Role of Amyloid-beta Oligomers in Toxicity, Propagation, and Immunotherapy.
Sengupta U, Nilson AN, Kayed R. Sengupta U, et al. EBioMedicine. 2016 Apr;6:42-49. doi: 10.1016/j.ebiom.2016.03.035. Epub 2016 Apr 5. EBioMedicine. 2016. PMID: 27211547 Free PMC article. Review.
The incidence of Alzheimer's disease (AD) is growing every day and finding an effective treatment is becoming more vital. Amyloid-beta (Abeta) has been the focus of research for several decades. ...
The incidence of Alzheimer's disease (AD) is growing every day and finding an effective treatment is becoming more vital. Amyloid- …
Amyloid Beta (Abeta) Peptide and Factors that Play Important Roles in Alzheimer's Disease.
Jamasbi E, Wade JD, Separovic F, Hossain MA. Jamasbi E, et al. Curr Med Chem. 2016;23(9):884-92. doi: 10.2174/0929867323666160229113911. Curr Med Chem. 2016. PMID: 26923680 Review.
Amyloid beta peptide (Abeta) is recognised as a main feature of Alzheimer's disease (AD). ...
Amyloid beta peptide (Abeta) is recognised as a main feature of Alzheimer's disease (AD). ...
Cross beta amyloid assemblies as complex catalytic machinery.
Pal S, Goswami S, Das D. Pal S, et al. Chem Commun (Camb). 2021 Aug 3;57(62):7597-7609. doi: 10.1039/d1cc02880d. Chem Commun (Camb). 2021. PMID: 34278403
Inspired by Nature's ingenuity in creating complex catalytic structures for exotic functions, short peptide-based cross beta amyloid sequences have been shown to access intricate binding surfaces demonstrating the traits of extant enzymes and proteins. ...Herein, we …
Inspired by Nature's ingenuity in creating complex catalytic structures for exotic functions, short peptide-based cross beta amylo
Focus on: amyloid beta.
Normando EM, Coxon KM, Guo L, Cordeiro MF. Normando EM, et al. Exp Eye Res. 2009 Oct;89(4):446-7. doi: 10.1016/j.exer.2009.05.004. Epub 2009 May 21. Exp Eye Res. 2009. PMID: 19464289 Review. No abstract available.
77,389 results
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