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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 3
1945 7
1946 20
1947 28
1948 20
1949 28
1950 24
1951 19
1952 32
1953 49
1954 42
1955 41
1956 30
1957 37
1958 41
1959 44
1960 52
1961 55
1962 61
1963 86
1964 84
1965 101
1966 85
1967 83
1968 129
1969 123
1970 137
1971 179
1972 178
1973 193
1974 217
1975 642
1976 599
1977 546
1978 546
1979 584
1980 635
1981 642
1982 726
1983 820
1984 931
1985 981
1986 983
1987 917
1988 951
1989 1072
1990 1123
1991 1129
1992 1130
1993 1046
1994 1089
1995 1156
1996 1162
1997 1187
1998 1243
1999 1265
2000 1347
2001 1331
2002 1369
2003 1419
2004 1539
2005 1642
2006 1742
2007 1890
2008 1938
2009 2116
2010 2213
2011 2474
2012 2778
2013 2924
2014 3096
2015 3131
2016 3348
2017 3532
2018 3819
2019 4073
2020 4503
2021 4811
2022 5009
2023 4572
2024 1922

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86,444 results

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Page 1
Crossroads of Antibiotic Resistance and Biosynthesis.
Wencewicz TA. Wencewicz TA. J Mol Biol. 2019 Aug 23;431(18):3370-3399. doi: 10.1016/j.jmb.2019.06.033. Epub 2019 Jul 6. J Mol Biol. 2019. PMID: 31288031 Free PMC article. Review.
The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic producers are an integral part of the growing antibiotic resistance threat. ...Some case studies of synergistic antibiotic combinations, adjuvants, and hybrid …
The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic producers are an integral part of …
History of Antibiotics Research.
Mohr KI. Mohr KI. Curr Top Microbiol Immunol. 2016;398:237-272. doi: 10.1007/82_2016_499. Curr Top Microbiol Immunol. 2016. PMID: 27738915 Review.
that the first milestones within the history of antibiotics research were set. Then new discoveries accelerated rapidly: Bacteria could be isolated and cultured and were identified as possible agents of diseases as well as producers of bioactive metabolites. …
that the first milestones within the history of antibiotics research were set. Then new discoveries accelerated rapidly: Bacteria cou …
Global Threat of Carbapenem-Resistant Gram-Negative Bacteria.
Jean SS, Harnod D, Hsueh PR. Jean SS, et al. Front Cell Infect Microbiol. 2022 Mar 15;12:823684. doi: 10.3389/fcimb.2022.823684. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35372099 Free PMC article. Review.
It has been determined that tigecycline is suitable for the treatment of bloodstream infections owing to GNB, with a minimum inhibitory concentration of 0.5 mg/L. Ceftazidime-avibactam is a last-resort antibiotic against GNB of Ambler class A/C/D enzyme-producers an …
It has been determined that tigecycline is suitable for the treatment of bloodstream infections owing to GNB, with a minimum inhibitory conc …
A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance.
Bell BG, Schellevis F, Stobberingh E, Goossens H, Pringle M. Bell BG, et al. BMC Infect Dis. 2014 Jan 9;14:13. doi: 10.1186/1471-2334-14-13. BMC Infect Dis. 2014. PMID: 24405683 Free PMC article. Review.
We therefore chose to assess the relationship between the antibiotic resistance pattern of bacteria circulating in the community and the consumption of antibiotics in the community. ...Increased consumption of antibiotics may not only produce greater r …
We therefore chose to assess the relationship between the antibiotic resistance pattern of bacteria circulating in the community and …
Antibiotics produced by Streptomyces.
Procópio RE, Silva IR, Martins MK, Azevedo JL, Araújo JM. Procópio RE, et al. Braz J Infect Dis. 2012 Sep-Oct;16(5):466-71. doi: 10.1016/j.bjid.2012.08.014. Epub 2012 Sep 11. Braz J Infect Dis. 2012. PMID: 22975171 Free article. Review.
The most interesting property of Streptomyces is the ability to produce bioactive secondary metabolites, such as antifungals, antivirals, antitumorals, anti-hypertensives, immunosuppressants, and especially antibiotics. ...Self-medication and overuse of antibioti …
The most interesting property of Streptomyces is the ability to produce bioactive secondary metabolites, such as antifungals, antivir …
Antibiotic discovery through microbial interactions.
Zhang C, Straight PD. Zhang C, et al. Curr Opin Microbiol. 2019 Oct;51:64-71. doi: 10.1016/j.mib.2019.06.006. Epub 2019 Jul 22. Curr Opin Microbiol. 2019. PMID: 31344518 Review.
Microorganisms produce biologically active natural products, some of which are useful as antibiotics and other medicines. ...Although the pace of discovery has slowed dramatically, new approaches to identifying antibiotics show promise for the future. Among m …
Microorganisms produce biologically active natural products, some of which are useful as antibiotics and other medicines. ...A …
Antibiotic glycosyltransferases.
Walsh CT, Losey HC, Freel Meyers CL. Walsh CT, et al. Biochem Soc Trans. 2003 Jun;31(Pt 3):487-92. doi: 10.1042/bst0310487. Biochem Soc Trans. 2003. PMID: 12773141 Review.
In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycosyltransferases in the latter stages of the pathways. Two glycosylation pathways will be examined: the glycopeptide antibiotics of the …
In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycos …
Discovery of a Polyamino Acid Antibiotic Solely Comprising l-beta-Lysine by Potential Producer Prioritization-Guided Genome Mining.
Yamanaka K, Fukumoto H, Yoshimura N, Arakawa K, Kato Y, Hamano Y, Oikawa T. Yamanaka K, et al. ACS Chem Biol. 2022 Jan 21;17(1):171-180. doi: 10.1021/acschembio.1c00832. Epub 2021 Dec 10. ACS Chem Biol. 2022. PMID: 34886659
We report here the rational discovery of an unexplored cationic homo polyamino acid (CHPA) antibiotic by potential producer prioritization-guided genome mining. Mining the genome of gamma-poly-d-diaminobutyric acid (poly-d-Dab)-producing Streptoalloteichus hi …
We report here the rational discovery of an unexplored cationic homo polyamino acid (CHPA) antibiotic by potential producer pr …
Comparison of Antibiotic Resistance Mechanisms in Antibiotic-Producing and Pathogenic Bacteria.
Ogawara H. Ogawara H. Molecules. 2019 Sep 21;24(19):3430. doi: 10.3390/molecules24193430. Molecules. 2019. PMID: 31546630 Free PMC article. Review.
Antibiotic resistance poses a tremendous threat to human health. To overcome this problem, it is essential to know the mechanism of antibiotic resistance in antibiotic-producing and pathogenic bacteria. This paper deals with this problem from four poin …
Antibiotic resistance poses a tremendous threat to human health. To overcome this problem, it is essential to know the mechanism of …
Holomycin, an Antibiotic Secondary Metabolite, Is Required for Biofilm Formation by the Native Producer Photobacterium galatheae S2753.
Zhang SD, Isbrandt T, Lindqvist LL, Larsen TO, Gram L. Zhang SD, et al. Appl Environ Microbiol. 2021 May 11;87(11):e00169-21. doi: 10.1128/AEM.00169-21. Print 2021 May 11. Appl Environ Microbiol. 2021. PMID: 33771780 Free PMC article.
While the effects of antibiotics on microorganisms are widely studied, it remains less well understood how antibiotics affect the physiology of the native producing organisms. ...Here, we studied the effects of the antibiotic holomycin on its native …
While the effects of antibiotics on microorganisms are widely studied, it remains less well understood how antibiotics affect …
86,444 results
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