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Page 1
Showing results for paigen
Search for apigen instead (1 results)
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y. Huang X, et al. Cell Mol Gastroenterol Hepatol. 2022;14(1):1-26. doi: 10.1016/j.jcmgh.2022.03.006. Epub 2022 Mar 31. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35367665 Free PMC article.
METHODS: C57BL/6J wild-type and macrophage SCAP-specific knockout mice (SCAP(deltaM)) were subjected to Paigen diet (PD) feeding induced lean NAFLD. Inflammation and lipid metabolism of adipose and liver were evaluated. ...
METHODS: C57BL/6J wild-type and macrophage SCAP-specific knockout mice (SCAP(deltaM)) were subjected to Paigen diet (PD) feeding indu …
Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner.
Lawrie A, Hameed AG, Chamberlain J, Arnold N, Kennerley A, Hopkinson K, Pickworth J, Kiely DG, Crossman DC, Francis SE. Lawrie A, et al. Am J Pathol. 2011 Oct;179(4):1693-705. doi: 10.1016/j.ajpath.2011.06.037. Epub 2011 Aug 9. Am J Pathol. 2011. PMID: 21835155 Free PMC article.
Male IL-1R1(-/-), ApoE(-/-), and ApoE(-/-)/IL-1R1(-/-) mice were fed regular chow or a high-fat diet (Paigen diet) for 8 weeks before phenotyping for PAH. No abnormal phenotype was observed in the IL-1R1(-/-) mice. ...
Male IL-1R1(-/-), ApoE(-/-), and ApoE(-/-)/IL-1R1(-/-) mice were fed regular chow or a high-fat diet (Paigen diet) for 8 weeks before …
An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats.
Nozako M, Koyama T, Nagano C, Sato M, Matsumoto S, Mitani K, Yasufuku R, Kohashi M, Yoshikawa T. Nozako M, et al. PLoS One. 2015 Nov 25;10(11):e0143979. doi: 10.1371/journal.pone.0143979. eCollection 2015. PLoS One. 2015. PMID: 26606054 Free PMC article.
In this study, we investigated the influence of an atherogenic Paigen diet (PD) on the progression of nephropathy in spontaneous type 2 diabetic OLETF rats. ...
In this study, we investigated the influence of an atherogenic Paigen diet (PD) on the progression of nephropathy in spontaneous type …
Lactobacillus reuteri CCFM8631 Alleviates Hypercholesterolaemia Caused by the Paigen Atherogenic Diet by Regulating the Gut Microbiota.
Wang Q, He Y, Li X, Zhang T, Liang M, Wang G, Zhao J, Zhang H, Chen W. Wang Q, et al. Nutrients. 2022 Mar 17;14(6):1272. doi: 10.3390/nu14061272. Nutrients. 2022. PMID: 35334930 Free PMC article.
In this study, Lactobacillus reuteri CCFM8631 treatment was shown to decrease plasma total cholesterol (TC), low-density lipoprotein-cholesterol, aspartate transaminase, alanine transaminase and trimethylamine N-oxide concentrations, decrease liver TC and malondialdehyde concentr …
In this study, Lactobacillus reuteri CCFM8631 treatment was shown to decrease plasma total cholesterol (TC), low-density lipoprotein-cholest …
PRDM9 and Its Role in Genetic Recombination.
Paigen K, Petkov PM. Paigen K, et al. Trends Genet. 2018 Apr;34(4):291-300. doi: 10.1016/j.tig.2017.12.017. Epub 2018 Jan 21. Trends Genet. 2018. PMID: 29366606 Free PMC article. Review.
Evaluation of Antiatherogenic Properties of Ezetimibe Using (3)H-Labeled Low-Density-Lipoprotein Cholesterol and (99m)Tc-cAbVCAM1-5 SPECT in ApoE(-/-) Mice Fed the Paigen Diet.
Dumas LS, Briand F, Clerc R, Brousseau E, Montemagno C, Ahmadi M, Bacot S, Soubies A, Perret P, Riou LM, Devoogdt N, Lahoutte T, Barone-Rochette G, Fagret D, Ghezzi C, Sulpice T, Broisat A. Dumas LS, et al. J Nucl Med. 2017 Jul;58(7):1088-1093. doi: 10.2967/jnumed.116.177279. Epub 2017 Mar 9. J Nucl Med. 2017. PMID: 28280218 Free article.
Here, we investigated the mechanisms by which inhibition of intestinal cholesterol absorption might contribute to the clinically observed reduction in cardiovascular events by evaluating its effect on inflammatory plaque development in apolipoprotein E(-/-) mice. Methods: Apolipo …
Here, we investigated the mechanisms by which inhibition of intestinal cholesterol absorption might contribute to the clinically observed re …
Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.
Yesilaltay A, Daniels K, Pal R, Krieger M, Kocher O. Yesilaltay A, et al. PLoS One. 2009 Dec 1;4(12):e8103. doi: 10.1371/journal.pone.0008103. PLoS One. 2009. PMID: 19956623 Free PMC article.
PRINCIPAL FINDINGS: Here, we have examined the effects of PDZK1 deficiency in apoE KO mice fed with the atherogenic 'Paigen' diet for three months. Relative to apoE KO, PDZK1/apoE double KO (dKO) mice showed increased plasma lipids (33% increase in total cholesterol; 49 % …
PRINCIPAL FINDINGS: Here, we have examined the effects of PDZK1 deficiency in apoE KO mice fed with the atherogenic 'Paigen' diet for …
Purple perilla frutescens extracts containing α-asarone inhibit inflammatory atheroma formation and promote hepatic HDL cholesterol uptake in dyslipidemic apoE-deficient mice.
Park SH, Sim YE, Kang MK, Kim DY, Kang IJ, Lim SS, Kang YH. Park SH, et al. Nutr Res Pract. 2023 Dec;17(6):1099-1112. doi: 10.4162/nrp.2023.17.6.1099. Epub 2023 Aug 28. Nutr Res Pract. 2023. PMID: 38053825 Free PMC article.
RESULTS: The Paigen's diet reduced body weight gain in apoE-deficient mice, which was not restored by PPE or alpha-asarone. ...Paigen's diet-induced systemic inflammation was reduced in PPE or alpha-asarone-treated apoE-deficient mice. ...
RESULTS: The Paigen's diet reduced body weight gain in apoE-deficient mice, which was not restored by PPE or alpha-asarone. ...Pai …
Sex-specific hepatic lipid and bile acid metabolism alterations in Fancd2-deficient mice following dietary challenge.
Moore ES, Daugherity EK, Karambizi DI, Cummings BP, Behling-Kelly E, Schaefer DMW, Southard TL, McFadden JW, Weiss RS. Moore ES, et al. J Biol Chem. 2019 Oct 25;294(43):15623-15637. doi: 10.1074/jbc.RA118.005729. Epub 2019 Aug 21. J Biol Chem. 2019. PMID: 31434739 Free PMC article.
Fancd2(-/-) and wildtype (WT) mice were fed a standard diet (SD), a diet enriched in fat, cholesterol, and cholic acid (Paigen diet), or a diet enriched in lipid alone (high-fat diet (HFD)). Fancd2(-/-) mice developed hepatobiliary disease and exhibited decreased survival …
Fancd2(-/-) and wildtype (WT) mice were fed a standard diet (SD), a diet enriched in fat, cholesterol, and cholic acid (Paigen diet), …
436 results