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Showing results for apelin
Your search for apolin retrieved no results
Targeting the apelin system for the treatment of cardiovascular diseases.
Chapman FA, Maguire JJ, Newby DE, Davenport AP, Dhaun N. Chapman FA, et al. Cardiovasc Res. 2023 Dec 30;119(17):2683-2696. doi: 10.1093/cvr/cvad171. Cardiovasc Res. 2023. PMID: 37956047 Free PMC article. Review.
Despite currently available treatments, there remains a huge burden of cardiovascular disease-associated morbidity for patients and healthcare systems, and newer treatments are needed. The apelin system, comprising the apelin receptor and its two endogenous ligands …
Despite currently available treatments, there remains a huge burden of cardiovascular disease-associated morbidity for patients and healthca …
Apelin/APJ system in inflammation.
Wang X, Zhang L, Li P, Zheng Y, Yang Y, Ji S. Wang X, et al. Int Immunopharmacol. 2022 Aug;109:108822. doi: 10.1016/j.intimp.2022.108822. Epub 2022 May 20. Int Immunopharmacol. 2022. PMID: 35605524 Review.
Recent studies indicate that the apelin/APJ system plays an important role in physiological and pathophysiological situations. ...Further, the mechanistic basis by which apelin regulates various inflammation-related diseases is analyzed. ...
Recent studies indicate that the apelin/APJ system plays an important role in physiological and pathophysiological situations. ...Fur …
The exerkine apelin reverses age-associated sarcopenia.
Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradère JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C. Vinel C, et al. Nat Med. 2018 Sep;24(9):1360-1371. doi: 10.1038/s41591-018-0131-6. Epub 2018 Jul 30. Nat Med. 2018. PMID: 30061698 Clinical Trial.
Mice deficient in either apelin or its receptor (APLNR) presented dramatic alterations in muscle function with increasing age. ...Taken together, these findings revealed positive regulatory feedback between physical activity, apelin and muscle function and identifie …
Mice deficient in either apelin or its receptor (APLNR) presented dramatic alterations in muscle function with increasing age. ...Tak …
Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential.
Pang B, Jiang YR, Xu JY, Shao DX, Hao LY. Pang B, et al. Eur J Pharmacol. 2023 Jun 15;949:175727. doi: 10.1016/j.ejphar.2023.175727. Epub 2023 Apr 14. Eur J Pharmacol. 2023. PMID: 37062502 Review.
Apelin has been proven to regulate cardiac hypertrophy through various pathways. And an increasing number of studies on ELABELA, the newly discovered endogenous ligand, suggest it can alleviate cardiac hypertrophy through mechanisms similar or different to apelin. I …
Apelin has been proven to regulate cardiac hypertrophy through various pathways. And an increasing number of studies on ELABELA, the …
Review: Apelin in disease.
Antushevich H, Wójcik M. Antushevich H, et al. Clin Chim Acta. 2018 Aug;483:241-248. doi: 10.1016/j.cca.2018.05.012. Epub 2018 May 8. Clin Chim Acta. 2018. PMID: 29750964 Review.
Apelin, a regulatory peptide, is a ligand of the APJ receptor that belongs to the G protein-coupled receptor family. Apelin and APJ are widely distributed in the body and play potential physiological roles in the cytoprotection of many internal organs. ...
Apelin, a regulatory peptide, is a ligand of the APJ receptor that belongs to the G protein-coupled receptor family. Apelin an …
Apelin C-Terminal Fragments: Biological Properties and Therapeutic Potential.
Pisarenko OI, Studneva IM. Pisarenko OI, et al. Biochemistry (Mosc). 2023 Nov;88(11):1874-1889. doi: 10.1134/S0006297923110160. Biochemistry (Mosc). 2023. PMID: 38105205 Review.
In the recent years, it has been established that C-terminal fragments of apelin, an endogenous ligand of the APJ receptor, reduce metabolic and functional disorders in experimental heart damage. The review presents literature data and generalized results of our own experi …
In the recent years, it has been established that C-terminal fragments of apelin, an endogenous ligand of the APJ receptor, reduce me …
Apelin/APJ system: an emerging therapeutic target for neurological diseases.
Li A, Zhao Q, Chen L, Li Z. Li A, et al. Mol Biol Rep. 2023 Feb;50(2):1639-1653. doi: 10.1007/s11033-022-08075-9. Epub 2022 Nov 15. Mol Biol Rep. 2023. PMID: 36378421 Free PMC article. Review.
This article reviews the role of apelin/APJ system in neurological diseases. In detail, apelin/APJ system can relieve acute brain injury including subarachnoid hemorrhage, traumatic brain injury, and ischemic stroke. ...However, apelin/APJ system exacerbates …
This article reviews the role of apelin/APJ system in neurological diseases. In detail, apelin/APJ system can relieve acute br …
Apelin/Apelin receptor: A new therapeutic target in Polycystic Ovary Syndrome.
Liu Q, Jiang J, Shi Y, Mo Z, Li M. Liu Q, et al. Life Sci. 2020 Nov 1;260:118310. doi: 10.1016/j.lfs.2020.118310. Epub 2020 Aug 21. Life Sci. 2020. PMID: 32835696 Review.
Studies have shown that Apelin/apelin-receptor also expressed in ovary such as follicles, granulosa cells. ...These indicate that the Apelin/apelin-receptor play an important role in the development of follicle. ...
Studies have shown that Apelin/apelin-receptor also expressed in ovary such as follicles, granulosa cells. ...These indicate t …
Apelin and Vasopressin: The Yin and Yang of Water Balance.
Girault-Sotias PE, Gerbier R, Flahault A, de Mota N, Llorens-Cortes C. Girault-Sotias PE, et al. Front Endocrinol (Lausanne). 2021 Nov 22;12:735515. doi: 10.3389/fendo.2021.735515. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34880830 Free PMC article. Review.
Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions. ...In patients with the syndrome of inappropriate antidiuresis, in which vasopressin hypersecretion leads to hyponatremia, the balance between …
Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions. ...In …
Apelin/APJ system: A novel therapeutic target for locomotor system diseases.
Luo J, Liu W, Feng F, Chen L. Luo J, et al. Eur J Pharmacol. 2021 Sep 5;906:174286. doi: 10.1016/j.ejphar.2021.174286. Epub 2021 Jun 24. Eur J Pharmacol. 2021. PMID: 34174264 Review.
Apelin is an endogenous ligand of G protein-coupled receptor APJ. ...Considering the pleiotropic effects of apelin on locomotor system, apelin/APJ system may be an important therapeutic target for locomotor system diseases....
Apelin is an endogenous ligand of G protein-coupled receptor APJ. ...Considering the pleiotropic effects of apelin on locomoto …
2,536 results

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