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Showing results for apollon
Search for apoplon instead (1 results)
APOLLON Study and Others.
Erol Ç. Erol Ç. Anatol J Cardiol. 2023 Sep;27(9):503. doi: 10.14744/AnatolJCardiol.2023.9. Anatol J Cardiol. 2023. PMID: 37655738 Free PMC article. No abstract available.
Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma.
Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, Chen S, Wang Q, Shen X, Xue R, Dong L. Zhang S, et al. Oncotarget. 2014 Aug 30;5(16):7183-97. doi: 10.18632/oncotarget.2293. Oncotarget. 2014. PMID: 25216531 Free PMC article.
Apollon targeted Smac for degradation in ESCC cells. The effect of Apollon on chemosensitivity was reversed by Smac knockdown in ESCC cells. Taken together, our data show association of Apollon expression with chemotherapeutic response in ESCC, and provide a
Apollon targeted Smac for degradation in ESCC cells. The effect of Apollon on chemosensitivity was reversed by Smac knockdown
Apollon/Bruce is upregulated by Humanin.
Hashimoto Y, Takeshita Y, Naito M, Uchino H, Matsuoka M. Hashimoto Y, et al. Mol Cell Biochem. 2014 Dec;397(1-2):147-55. doi: 10.1007/s11010-014-2182-4. Epub 2014 Aug 20. Mol Cell Biochem. 2014. PMID: 25138702
Here we show that the Humanin signaling pathway via htHNR/JAKs/STAT3 increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins, and that overexpression of Apollon/Bruce inhibits neuronal death, ca …
Here we show that the Humanin signaling pathway via htHNR/JAKs/STAT3 increased the expression levels of mRNA and protein of Apollon/B …
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function.
Hao Y, Sekine K, Kawabata A, Nakamura H, Ishioka T, Ohata H, Katayama R, Hashimoto C, Zhang X, Noda T, Tsuruo T, Naito M. Hao Y, et al. Nat Cell Biol. 2004 Sep;6(9):849-60. doi: 10.1038/ncb1159. Epub 2004 Aug 8. Nat Cell Biol. 2004. PMID: 15300255
Apollon inhibits apoptosis, but its molecular and physiological function remains unclear. ...Targeted disruption of Apollon in mice caused embryonic and neonatal lethality. Notably, SMAC induced apoptosis in Apollon-deficient cells, but not in Apollon-
Apollon inhibits apoptosis, but its molecular and physiological function remains unclear. ...Targeted disruption of Apollon in
Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis.
Dorman SE, Nahid P, Kurbatova EV, Phillips PPJ, Bryant K, Dooley KE, Engle M, Goldberg SV, Phan HTT, Hakim J, Johnson JL, Lourens M, Martinson NA, Muzanyi G, Narunsky K, Nerette S, Nguyen NV, Pham TH, Pierre S, Purfield AE, Samaneka W, Savic RM, Sanne I, Scott NA, Shenje J, Sizemore E, Vernon A, Waja Z, Weiner M, Swindells S, Chaisson RE; AIDS Clinical Trials Group; Tuberculosis Trials Consortium. Dorman SE, et al. N Engl J Med. 2021 May 6;384(18):1705-1718. doi: 10.1056/NEJMoa2033400. N Engl J Med. 2021. PMID: 33951360 Free PMC article. Clinical Trial.
Apollon/RNF41 myocardial messenger RNA diagnoses cardiac allograft apoptosis in rejection.
Aharinejad S, Andrukhova O, Gmeiner M, Thomas A, Krenn K, Zuckermann A, Grimm M. Aharinejad S, et al. Transplantation. 2010 Jan 27;89(2):245-52. doi: 10.1097/TP.0b013e3181c3c690. Transplantation. 2010. PMID: 20098290
A method that could avoid discordant EMB analysis would be desirable. The apoptosis rate in EMB correlates with ACR severity. Apollon inhibits apoptosis, and RNF41 catalyzes its degradation. Whether tissue Apollon/RNF41 could diagnose ACR is not known. ...Increased …
A method that could avoid discordant EMB analysis would be desirable. The apoptosis rate in EMB correlates with ACR severity. Apollon
Expression and clinical significance of Apollon in renal carcinoma.
Guo H, Zhong W, Wang X, Pan B, Li F, Lu K, Su Z, Zhang S. Guo H, et al. Oncol Lett. 2016 Dec;12(6):5129-5135. doi: 10.3892/ol.2016.5349. Epub 2016 Nov 3. Oncol Lett. 2016. PMID: 28105219 Free PMC article.
The aim of the present study was to assess the association between renal carcinoma (RC) and Apollon expression, and to highlight the link between Apollon expression and the occurrence, development and prognosis of RC. ...There was a significant difference in T-stage …
The aim of the present study was to assess the association between renal carcinoma (RC) and Apollon expression, and to highlight the …
Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation.
Lopergolo A, Pennati M, Gandellini P, Orlotti NI, Poma P, Daidone MG, Folini M, Zaffaroni N. Lopergolo A, et al. Br J Cancer. 2009 Mar 10;100(5):739-46. doi: 10.1038/sj.bjc.6604927. Epub 2009 Feb 17. Br J Cancer. 2009. PMID: 19223905 Free PMC article.
Furthermore, the activation of caspase-3 seemed to be essential for the induction of apoptosis after Apollon knockdown, as the Apollon-specific siRNA had no effect on the viability of caspase-3-deficient, wild-type p53 MCF-7 cells or the ZR75.1 cells after RNA inter …
Furthermore, the activation of caspase-3 seemed to be essential for the induction of apoptosis after Apollon knockdown, as the Apo
Expression and clinical significance of Apollon in esophageal squamous cell carcinoma.
Li R, Chen BL, Zhou YW, Guo RW, Shuai MT, Zeng JX, Leng AM. Li R, et al. Mol Med Rep. 2016 Sep;14(3):1933-40. doi: 10.3892/mmr.2016.5473. Epub 2016 Jul 6. Mol Med Rep. 2016. PMID: 27432467 Free PMC article.
The aim of the present study was to assess the association between esophageal squamous cell carcinoma (ESCC) and Apollon expression levels, and to highlight the association between Apollon and the occurrence, development and prognosis of ESCC. ...The overexpression …
The aim of the present study was to assess the association between esophageal squamous cell carcinoma (ESCC) and Apollon expression l …
RNA interference-mediated validation of survivin and Apollon/BRUCE as new therapeutic targets for cancer therapy.
Pennati M, Millo E, Gandellini P, Folini M, Zaffaroni N. Pennati M, et al. Curr Top Med Chem. 2012;12(2):69-78. doi: 10.2174/156802612798919169. Curr Top Med Chem. 2012. PMID: 22196277 Review.
The present review summarizes the findings from studies relying on the use of RNAi-based approaches to functionally validate two members of the inhibitors of apoptosis protein family, survivin and Apollon/BRUCE, as new cancer therapeutic targets. Results collected thus far …
The present review summarizes the findings from studies relying on the use of RNAi-based approaches to functionally validate two members of …
197 results