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93 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
The probiotic Bacillus subtilis BS50 decreases gastrointestinal symptoms in healthy adults: a randomized, double-blind, placebo-controlled trial.
Garvey SM, Mah E, Blonquist TM, Kaden VN, Spears JL. Garvey SM, et al. Gut Microbes. 2022 Jan-Dec;14(1):2122668. doi: 10.1080/19490976.2022.2122668. Gut Microbes. 2022. PMID: 36269141 Free PMC article. Clinical Trial.
To help meet this demand, the safety and efficacy of daily supplementation of Bacillus subtilis BS50 for 6 weeks was investigated in a randomized, double-blind, placebo-controlled, parallel clinical trial of 76 healthy adults. ...In conclusion, the results suggest t …
To help meet this demand, the safety and efficacy of daily supplementation of Bacillus subtilis BS50 for 6 weeks was investiga …
Acute physiological effects following Bacillus subtilis DE111 oral ingestion - a randomised, double blinded, placebo-controlled study.
Colom J, Freitas D, Simon A, Khokhlova E, Mazhar S, Buckley M, Phipps C, Deaton J, Brodkorb A, Rea K. Colom J, et al. Benef Microbes. 2023 Mar 14;14(1):31-44. doi: 10.3920/BM2022.0081. Epub 2023 Feb 15. Benef Microbes. 2023. PMID: 36790091 Clinical Trial.
Previous studies using ileostomy samples from study participants demonstrated that the spore-forming probiotic Bacillus subtilis DE111() can germinate in the small intestine as early as 4 hours after ingestion. ...Acute B. subtilis DE111 ingestion had limited …
Previous studies using ileostomy samples from study participants demonstrated that the spore-forming probiotic Bacillus subtilis …
Bacillus Subtilis (BG01-4(TM)) Improves Self-Reported Symptoms for Constipation, Indigestion, and Dyspepsia: A Phase 1/2A Randomized Controlled Trial.
Patch C, Pearce AJ, Cheng M, Boyapati R, Brenna JT. Patch C, et al. Nutrients. 2023 Oct 24;15(21):4490. doi: 10.3390/nu15214490. Nutrients. 2023. PMID: 37960143 Free PMC article. Clinical Trial.
We conducted a double-blinded randomised controlled trial of a proprietary strain of deactivated Bacillus subtilis (BG01-4) high in branched-chain fatty acids (BCFA) to treat self-reported FGID. ...
We conducted a double-blinded randomised controlled trial of a proprietary strain of deactivated Bacillus subtilis (BG01-4) hi …
Bacillus subtilis DE111 intake may improve blood lipids and endothelial function in healthy adults.
Trotter RE, Vazquez AR, Grubb DS, Freedman KE, Grabos LE, Jones S, Gentile CL, Melby CL, Johnson SA, Weir TL. Trotter RE, et al. Benef Microbes. 2020 Nov 15;11(7):621-630. doi: 10.3920/BM2020.0039. Epub 2020 Nov 9. Benef Microbes. 2020. PMID: 33161737 Free PMC article. Clinical Trial.
Evidence exists for a positive correlation between Bifidobacterium and vascular function, glucose tolerance, and reduced systemic inflammation. Another probiotic species, Bacillus subtilis, has also been found to reduce cholesterol levels in human and animal models. …
Evidence exists for a positive correlation between Bifidobacterium and vascular function, glucose tolerance, and reduced systemic inflammati …
Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand: a phase 2, double-blind, randomised, placebo-controlled trial.
Piewngam P, Khongthong S, Roekngam N, Theapparat Y, Sunpaweravong S, Faroongsarng D, Otto M. Piewngam P, et al. Lancet Microbe. 2023 Feb;4(2):e75-e83. doi: 10.1016/S2666-5247(22)00322-6. Epub 2023 Jan 13. Lancet Microbe. 2023. PMID: 36646104 Free PMC article. Clinical Trial.
However, previous topical strategies targeting the nose or skin had little success, and oral antibiotic-based decolonisation is ill advised because of eradication of the microbiota and development of antibiotic resistance. We previously showed that the probiotic Bacillus …
However, previous topical strategies targeting the nose or skin had little success, and oral antibiotic-based decolonisation is ill advised …
Efficacy of Bacillus subtilis to replace in-feed antibiotics of broiler chickens under necrotic enteritis-challenged experiments: a systematic review and meta-analysis.
Ningsih N, Respati AN, Astuti D, Triswanto T, Purnamayanti L, Yano AA, Putra RP, Jayanegara A, Ratriyanto A, Irawan A. Ningsih N, et al. Poult Sci. 2023 Oct;102(10):102923. doi: 10.1016/j.psj.2023.102923. Epub 2023 Jul 6. Poult Sci. 2023. PMID: 37494807 Free PMC article.
Necrotic enteritis (NE) and coccidiosis are among the most prevalent infectious diseases in broiler chickens, contributing to large profitability losses. Bacillus subtilis is a promising direct-fed probiotic to counter various pathogens infection in broiler chickens …
Necrotic enteritis (NE) and coccidiosis are among the most prevalent infectious diseases in broiler chickens, contributing to large profitab …
Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial.
Wauters L, Slaets H, De Paepe K, Ceulemans M, Wetzels S, Geboers K, Toth J, Thys W, Dybajlo R, Walgraeve D, Biessen E, Verbeke K, Tack J, Van de Wiele T, Hellings N, Vanuytsel T. Wauters L, et al. Lancet Gastroenterol Hepatol. 2021 Oct;6(10):784-792. doi: 10.1016/S2468-1253(21)00226-0. Epub 2021 Aug 3. Lancet Gastroenterol Hepatol. 2021. PMID: 34358486 Clinical Trial.
METHODS: In this single-centre, randomised, double-blind, placebo-controlled pilot trial that took place at University Hospitals Leuven (Leuven, Belgium), adult patients (18 years) with functional dyspepsia (as defined by Rome IV criteria, on proton-pump inhibitors or off proton- …
METHODS: In this single-centre, randomised, double-blind, placebo-controlled pilot trial that took place at University Hospitals Leuven (Leu …
Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans.
Lefevre M, Racedo SM, Denayrolles M, Ripert G, Desfougères T, Lobach AR, Simon R, Pélerin F, Jüsten P, Urdaci MC. Lefevre M, et al. Regul Toxicol Pharmacol. 2017 Feb;83:54-65. doi: 10.1016/j.yrtph.2016.11.010. Epub 2016 Nov 5. Regul Toxicol Pharmacol. 2017. PMID: 27825987 Free article. Clinical Trial.
Bacillus subtilis CU1 is a recently described probiotic strain with beneficial effects on immune health in elderly subjects. ...Using a combination of 16S rDNA and gyrB nucleotide analyses, the species was identified as a member of the Bacillus subtilis …
Bacillus subtilis CU1 is a recently described probiotic strain with beneficial effects on immune health in elderly subjects. . …
Evaluation of Bacillus clausii CSI08, Bacillus megaterium MIT411 and a Bacillus cocktail on gastrointestinal health: a randomised, double-blind, placebo-controlled pilot study.
Rea K, Colom J, Simon EA, Khokhlova E, Mazhar S, Barrena M, Enrique M, Martorell P, Perez BA, Tortajada M, Phipps C, Deaton J. Rea K, et al. Benef Microbes. 2023 Apr 18;14(2):165-182. doi: 10.3920/BM2022.0117. Epub 2023 Apr 7. Benef Microbes. 2023. PMID: 37026366 Clinical Trial.
In the present study, the safety, tolerance and impact of 110(9) cfu Bacillus clausii CSI08, 110(9) cfu Bacillus megaterium MIT411 and a probiotic cocktail containing Bacillus subtilis DE111(), Bacillus megaterium MIT411, Bacillus coagula …
In the present study, the safety, tolerance and impact of 110(9) cfu Bacillus clausii CSI08, 110(9) cfu Bacillus megaterium MI …
Bacillus subtilis PB6 improves intestinal health of broiler chickens challenged with Clostridium perfringens-induced necrotic enteritis.
Jayaraman S, Thangavel G, Kurian H, Mani R, Mukkalil R, Chirakkal H. Jayaraman S, et al. Poult Sci. 2013 Feb;92(2):370-4. doi: 10.3382/ps.2012-02528. Poult Sci. 2013. PMID: 23300303 Free article. Clinical Trial.
The present study investigated the influence of a dietary supplement, Bacillus subtilis PB6, on performance, intestinal health, and gut integrity against C. perfringens-induced NE in broiler birds. Bacillus subtilis PB6 (ATCC-PTA 6737) is a natural str …
The present study investigated the influence of a dietary supplement, Bacillus subtilis PB6, on performance, intestinal health …
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