Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1957 1
1958 2
1959 2
1961 1
1962 2
1975 4
1977 1
1979 2
1980 1
1983 1
1984 1
1988 1
1989 1
1990 3
1991 1
1995 1
1998 1
2018 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Metabolism of beclamide, N-benzyl-3-chloropropionamide, in man.
Nicholls PJ, Ross MS, Luscombe DK. Nicholls PJ, et al. Xenobiotica. 1979 Feb;9(2):129-40. doi: 10.3109/00498257909038713. Xenobiotica. 1979. PMID: 433311
1. Following oral administration of [14C]beclamide to human subjects there was almost complete elimination of radioactivity in the urine within 48 h. 2. ...Six minor metabolites were also detected, of which the following were identified: benzoic acid (up to c. 7%), N-(4-hy …
1. Following oral administration of [14C]beclamide to human subjects there was almost complete elimination of radioactivity in the ur …
Metabolism of beclamide after a single oral dose in man: quantitative studies.
Ahmadi M, Nicholls PJ, Smith HJ, Spencer PS, Preet-Ryatt MS, Spragg BP. Ahmadi M, et al. J Pharm Pharmacol. 1995 Oct;47(10):876-8. doi: 10.1111/j.2042-7158.1995.tb05757.x. J Pharm Pharmacol. 1995. PMID: 8583359
A simple reverse phase HPLC assay is described for the determination of the anticonvulsant compound, beclamide and its 3- and 4-hydroxyphenyl metabolites in urine. Following oral administration of 1 g beclamide to a panel of healthy volunteers, less than 0.4% of the …
A simple reverse phase HPLC assay is described for the determination of the anticonvulsant compound, beclamide and its 3- and 4-hydro …
Studies on the masking of unpleasant taste of beclamide: microencapsulation and tabletting.
Ozer AY, Hincal AA. Ozer AY, et al. J Microencapsul. 1990 Jul-Sep;7(3):327-39. doi: 10.3109/02652049009021843. J Microencapsul. 1990. PMID: 2384836
Beclamide was microencapsulated in order to mask the taste, by a simple coacervation method using gelatin. ...The dissolution pattern of beclamide was first-order kinetic. Release rate constants, t50%, t90% and AUC values were calculated. ...
Beclamide was microencapsulated in order to mask the taste, by a simple coacervation method using gelatin. ...The dissolution pattern …
Anticonvulsants as adjuncts for the neuroleptic treatment of schizophrenic psychoses: a clinical study with beclamide.
Raptis C, Garcia-Borreguero D, Weber MM, Dose M, Bremer D, Emrich HM. Raptis C, et al. Acta Psychiatr Scand. 1990 Feb;81(2):162-7. doi: 10.1111/j.1600-0447.1990.tb06472.x. Acta Psychiatr Scand. 1990. PMID: 2183543 Clinical Trial.
A recent study showed an adjuvant effect of carbamazepine in the neuroleptic treatment of acute schizophrenic psychoses. Since beclamide (beta-chlorpropionamide) was reported to reduce the neuroleptic doses required, the combination haloperidol-beclamide was tested …
A recent study showed an adjuvant effect of carbamazepine in the neuroleptic treatment of acute schizophrenic psychoses. Since beclamide …
Comparison of the inhibitory action of aminobeclamide and beclamide on socially offensive behaviour.
Darmani NA, Sewell RD, Hasan MY, Nicholls PJ. Darmani NA, et al. J Pharm Pharmacol. 1990 Jun;42(6):447-9. doi: 10.1111/j.2042-7158.1990.tb06591.x. J Pharm Pharmacol. 1990. PMID: 1979631
The inhibitory effects of aminobeclamide (N-(p-aminobenzyl)-beta-chloropropionamide) on socially offensive behaviour has been studied and compared with those of the parent drug beclamide (N-benzyl-beta-chloropropionamide). Following oral administration in mice which had be …
The inhibitory effects of aminobeclamide (N-(p-aminobenzyl)-beta-chloropropionamide) on socially offensive behaviour has been studied and co …
Beclamide in intractable epilepsy: a controlled trial.
WILSON J, WALTON JN, NEWELL DJ. WILSON J, et al. Br Med J. 1959 May 16;1(5132):1275-8. doi: 10.1136/bmj.1.5132.1275. Br Med J. 1959. PMID: 13651708 Free PMC article. No abstract available.
Effects of beclamide on isolation-induced aggression and locomotor activity in mice.
Darmani NA, Sewell RD, Nicholls PJ. Darmani NA, et al. J Pharm Pharmacol. 1988 Dec;40(12):891-3. doi: 10.1111/j.2042-7158.1988.tb06297.x. J Pharm Pharmacol. 1988. PMID: 2907587
In addition, the highest dose of beclamide (250 mg kg-1 p.o.) did not significantly modify locomotor activity in mice. It was concluded that beclamide induced anti-aggressive effects at non-sedative doses. This anti-aggressive action was thought be at least partiall …
In addition, the highest dose of beclamide (250 mg kg-1 p.o.) did not significantly modify locomotor activity in mice. It was conclud …
Acute effects of beclamide on brain regional monoamine concentrations, their metabolites and radioligand binding studies.
Darmani NA, Sewell RD, Nicholls PJ. Darmani NA, et al. J Pharm Pharmacol. 1991 Jun;43(6):425-9. doi: 10.1111/j.2042-7158.1991.tb03502.x. J Pharm Pharmacol. 1991. PMID: 1717674
The effects of beclamide on regional brain monoamine levels and radioligand binding have been studied in rats. ...The concentrations of bioamines and their metabolites in the hypothalamus were unaffected by such acute beclamide treatment. In radioligand binding stud …
The effects of beclamide on regional brain monoamine levels and radioligand binding have been studied in rats. ...The concentrations …
Nydrane as an anticonvulsant.
KAYE N, JONES IH, WARRIER GK. KAYE N, et al. Br Med J. 1959 Mar 7;1(5122):627-9. doi: 10.1136/bmj.1.5122.627. Br Med J. 1959. PMID: 13629072 Free PMC article. No abstract available.
28 results