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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 1
1953 2
1954 2
1955 2
1956 5
1957 3
1958 2
1960 1
1962 1
1963 1
1964 4
1965 3
1966 7
1967 5
1968 6
1969 5
1970 5
1971 4
1972 9
1973 9
1974 5
1975 11
1976 5
1977 4
1978 4
1979 4
1980 5
1981 5
1982 10
1983 9
1984 11
1985 12
1986 7
1987 7
1988 8
1989 12
1990 10
1991 7
1992 10
1993 11
1994 5
1995 7
1996 14
1997 14
1998 19
1999 13
2000 24
2001 16
2002 29
2003 23
2004 27
2005 22
2006 27
2007 43
2008 41
2009 38
2010 39
2011 46
2012 48
2013 52
2014 43
2015 48
2016 51
2017 58
2018 57
2019 53
2020 56
2021 61
2022 65
2023 47
2024 33

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1,216 results

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Page 1
Effects of betaine on non-alcoholic liver disease.
Chen W, Xu M, Xu M, Wang Y, Zou Q, Xie S, Wang L. Chen W, et al. Nutr Res Rev. 2022 Jun;35(1):28-38. doi: 10.1017/S0954422421000056. Epub 2021 Apr 5. Nutr Res Rev. 2022. PMID: 33818349 Review.
The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) poses a growing challenge in terms of its prevention and treatment. The 'multiple hits' hypothesis of multiple insults, such as dietary fat intake, de novo lipogenesis, insulin resistance, oxidative str …
The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) poses a growing challenge in terms of its prevention and treat …
Role of betaine in liver disease-worth revisiting or has the die been cast?
Mukherjee S. Mukherjee S. World J Gastroenterol. 2020 Oct 14;26(38):5745-5748. doi: 10.3748/wjg.v26.i38.5745. World J Gastroenterol. 2020. PMID: 33132631 Free PMC article. Review.
Nonalcoholic steatohepatitis (NASH) is an important indication for liver transplantation in many Western countries due to the epidemic of obesity and insulin resistance. ...It seems reasonable to re-evaluate betaine in clinical trials for NASH and alcoholic liver …
Nonalcoholic steatohepatitis (NASH) is an important indication for liver transplantation in many Western countries due to the epidemi …
Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms.
Wang C, Ma C, Gong L, Dai S, Li Y. Wang C, et al. Eur J Pharmacol. 2021 Dec 5;912:174604. doi: 10.1016/j.ejphar.2021.174604. Epub 2021 Oct 28. Eur J Pharmacol. 2021. PMID: 34743980 Review.
In recent years, a large number of literatures have shown that betaine has good preventive and therapeutic effects on many liver diseases, including chemical or drug-induced liver injury, nonalcoholic fatty liver disease, alcoholic fatty liver d …
In recent years, a large number of literatures have shown that betaine has good preventive and therapeutic effects on many liver …
Betaine chemistry, roles, and potential use in liver disease.
Day CR, Kempson SA. Day CR, et al. Biochim Biophys Acta. 2016 Jun;1860(6):1098-106. doi: 10.1016/j.bbagen.2016.02.001. Epub 2016 Feb 2. Biochim Biophys Acta. 2016. PMID: 26850693 Free article. Review.
The abundance of both betaine and the betaine transporter in liver greatly exceeds that of other organs. ...MAJOR CONCLUSIONS: A significant amount of data from animal models of liver disease indicates that administration of betaine can halt and …
The abundance of both betaine and the betaine transporter in liver greatly exceeds that of other organs. ...MAJOR CONCL …
Betaine transport in kidney and liver: use of betaine in liver injury.
Kempson SA, Vovor-Dassu K, Day C. Kempson SA, et al. Cell Physiol Biochem. 2013;32(7):32-40. doi: 10.1159/000356622. Epub 2013 Dec 18. Cell Physiol Biochem. 2013. PMID: 24429813 Free article. Review.
Betaine is much more abundant in kidney and liver compared to other mammalian organs. ...Entry of betaine into liver cells is a necessary first step for its action at the cellular level. ...
Betaine is much more abundant in kidney and liver compared to other mammalian organs. ...Entry of betaine into liver …
Betaine, ethanol, and the liver: a review.
Barak AJ, Beckenhauer HC, Tuma DJ. Barak AJ, et al. Alcohol. 1996 Jul-Aug;13(4):395-8. doi: 10.1016/0741-8329(96)00030-4. Alcohol. 1996. PMID: 8836329 Review.
Concomitant with the betaine-generated SAM, ethanol-induced hepatic fatty infiltration was ameliorated. In view of the fact that SAM has already been used successfully in the treatment of human maladies, including liver dysfunction, betaine, shown to protect …
Concomitant with the betaine-generated SAM, ethanol-induced hepatic fatty infiltration was ameliorated. In view of the fact that SAM …
Role of betaine in liver injury induced by the exposure to ionizing radiation.
Shedid SM, Abdel-Magied N, Saada HN. Shedid SM, et al. Environ Toxicol. 2019 Feb;34(2):123-130. doi: 10.1002/tox.22664. Epub 2018 Oct 11. Environ Toxicol. 2019. PMID: 30311401
The objective of this study was to investigate the influence of betaine on radiation-induced liver damage. Animals were exposed to 9 Gy applied in 3 doses of 3 Gy/wk. ...In conclusion, betaine through its antioxidant activity and by enhancing liver det …
The objective of this study was to investigate the influence of betaine on radiation-induced liver damage. Animals were expose …
Effect of Betaine Supplementation on Liver Tissue and Ultrastructural Changes in Methionine-Choline-Deficient Diet-Induced NAFLD.
Vesković M, Labudović-Borović M, Mladenović D, Jadžić J, Jorgačević B, Vukićević D, Vučević D, Radosavljević T. Vesković M, et al. Microsc Microanal. 2020 Oct;26(5):997-1006. doi: 10.1017/S1431927620024265. Microsc Microanal. 2020. PMID: 32782033
The aim of this study was to examine the effect of betaine on ultrastructural changes in the mouse liver with methionine- and choline-deficient (MCD) diet-induced NAFLD. ...Liver samples were taken for pathohistology and transmission electron microscopy. ...
The aim of this study was to examine the effect of betaine on ultrastructural changes in the mouse liver with methionine- and …
Betaine in ameliorating alcohol-induced hepatic steatosis.
Rehman A, Mehta KJ. Rehman A, et al. Eur J Nutr. 2022 Apr;61(3):1167-1176. doi: 10.1007/s00394-021-02738-2. Epub 2021 Nov 24. Eur J Nutr. 2022. PMID: 34817678 Free PMC article. Review.
Alcohol-associated liver disease (AALD) is one of most common chronic liver diseases. ...Despite its therapeutic potential, very few clinical trials have examined betaine's effect on alcohol-induced hepatic lipid accumulation. This review will provide further …
Alcohol-associated liver disease (AALD) is one of most common chronic liver diseases. ...Despite its therapeutic potential, ve …
Betaine attenuates chronic alcohol-induced fatty liver by broadly regulating hepatic lipid metabolism.
Yang W, Huang L, Gao J, Wen S, Tai Y, Chen M, Huang Z, Liu R, Tang C, Li J. Yang W, et al. Mol Med Rep. 2017 Oct;16(4):5225-5234. doi: 10.3892/mmr.2017.7295. Epub 2017 Aug 21. Mol Med Rep. 2017. PMID: 28849079 Free PMC article.
Betaine has previously been demonstrated to protect the liver against alcohol-induced fat accumulation. ...The present study aimed to investigate the effect of betaine on alcoholic simple fatty liver and hepatic lipid metabolism disorders. ...
Betaine has previously been demonstrated to protect the liver against alcohol-induced fat accumulation. ...The present study a …
1,216 results