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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1977 1
1978 1
1980 3
1981 1
1982 1
1983 2
1985 1
1986 1
1988 2
1990 1
1991 3
1992 1
1993 1
1994 1
1996 1
1997 2
1998 1
2001 1
2002 2
2003 1
2004 6
2005 7
2006 7
2007 7
2008 13
2009 10
2010 9
2011 12
2012 17
2013 18
2014 7
2015 11
2016 18
2017 18
2018 19
2019 23
2020 37
2021 34
2022 43
2023 46
2024 17

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360 results

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Page 1
Pharmacokinetics and pharmacodynamics of cannabinoids.
Grotenhermen F. Grotenhermen F. Clin Pharmacokinet. 2003;42(4):327-60. doi: 10.2165/00003088-200342040-00003. Clin Pharmacokinet. 2003. PMID: 12648025 Review.
However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered modulators of the endogenous cannabinoid system are also promising candidates for clinical research and therapeutic uses. Cannabinoid …
However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered mod …
The role of cannabinoids in pain modulation in companion animals.
Miranda-Cortés A, Mota-Rojas D, Crosignani-Outeda N, Casas-Alvarado A, Martínez-Burnes J, Olmos-Hernández A, Mora-Medina P, Verduzco-Mendoza A, Hernández-Ávalos I. Miranda-Cortés A, et al. Front Vet Sci. 2023 Jan 4;9:1050884. doi: 10.3389/fvets.2022.1050884. eCollection 2022. Front Vet Sci. 2023. PMID: 36686189 Free PMC article. Review.
The use of cannabinoids in both veterinary and human medicine is controversial for legal and ethical reasons. ...This review aims to examine the role of cannabinoids in pain modulation by analyzing scientific findings regarding the signaling pathways of the endocann …
The use of cannabinoids in both veterinary and human medicine is controversial for legal and ethical reasons. ...This review aims to …
Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants.
van Breemen RB, Muchiri RN, Bates TA, Weinstein JB, Leier HC, Farley S, Tafesse FG. van Breemen RB, et al. J Nat Prod. 2022 Jan 28;85(1):176-184. doi: 10.1021/acs.jnatprod.1c00946. Epub 2022 Jan 10. J Nat Prod. 2022. PMID: 35007072 Free PMC article.
Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein. .. …
Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid aci …
Strategies for enhancing the oral bioavailability of cannabinoids.
Bar-Hai A, Domb AJ, Hoffman A. Bar-Hai A, et al. Expert Opin Drug Metab Toxicol. 2022 May;18(5):313-322. doi: 10.1080/17425255.2022.2099837. Epub 2022 Jul 18. Expert Opin Drug Metab Toxicol. 2022. PMID: 35818714
INTRODUCTION: Oral administration of cannabinoids is a convenient route of administration in many cases. To enhance the poor and variable bioavailability of cannabinoids, selected strategies utilizing proper delivery systems have been designed. ...EXPERT OPIN …
INTRODUCTION: Oral administration of cannabinoids is a convenient route of administration in many cases. To enhance the poor and vari …
Cannabidiol: pharmacology and therapeutic targets.
Britch SC, Babalonis S, Walsh SL. Britch SC, et al. Psychopharmacology (Berl). 2021 Jan;238(1):9-28. doi: 10.1007/s00213-020-05712-8. Epub 2020 Nov 21. Psychopharmacology (Berl). 2021. PMID: 33221931 Free PMC article. Review.
The scientific evidence supporting these claims largely arises not from controlled clinical trials, but from the recognition that CBD has numerous biological targets. Yet, CBD is commonly consumed and often in over-the-counter products that are unapproved and of unknown co …
The scientific evidence supporting these claims largely arises not from controlled clinical trials, but from the recognition that CBD has nu …
Mechanisms of Action and Pharmacokinetics of Cannabis.
Chayasirisobhon S. Chayasirisobhon S. Perm J. 2020 Dec;25:1-3. doi: 10.7812/TPP/19.200. Perm J. 2020. PMID: 33635755 Free PMC article.
At least 100 cannabis species are compounds known as cannabinoids, a molecule with a 21-carbon terpenophenolic skeleton. Cannabinoids produce more than 100 naturally occurring chemicals, the most abundant of which are delta-9-tetrahydrocannabinol (THC), cannabidiol …
At least 100 cannabis species are compounds known as cannabinoids, a molecule with a 21-carbon terpenophenolic skeleton. Cannabino …
Cannabidiol in canine epilepsy.
Potschka H, Bhatti SFM, Tipold A, McGrath S. Potschka H, et al. Vet J. 2022 Dec;290:105913. doi: 10.1016/j.tvjl.2022.105913. Epub 2022 Oct 6. Vet J. 2022. PMID: 36209995 Free article.
Moreover, social media and public pressure has sparked a renewed awareness of cannabinoids, which have been used for epilepsy since ancient times. Unfortunately, at this moment veterinarians and veterinary neurologists have difficulty prescribing cannabinoids becaus …
Moreover, social media and public pressure has sparked a renewed awareness of cannabinoids, which have been used for epilepsy since a …
The Basal Pharmacology of Palmitoylethanolamide.
Rankin L, Fowler CJ. Rankin L, et al. Int J Mol Sci. 2020 Oct 26;21(21):7942. doi: 10.3390/ijms21217942. Int J Mol Sci. 2020. PMID: 33114698 Free PMC article. Review.
In terms of its pharmacokinetic properties, most work has been undertaken upon designing formulations for its absorption and upon characterising the enzymes involved in its metabolism, but little is known about its bioavailability, tissue distribution, and excretion pathwa …
In terms of its pharmacokinetic properties, most work has been undertaken upon designing formulations for its absorption and upon characteri …
Pharmacology of cannabinoids in the treatment of epilepsy.
Gaston TE, Friedman D. Gaston TE, et al. Epilepsy Behav. 2017 May;70(Pt B):313-318. doi: 10.1016/j.yebeh.2016.11.016. Epub 2017 Jan 10. Epilepsy Behav. 2017. PMID: 28087250 Review.
We describe the absorption, distribution, metabolism, and excretion of each of the above mentioned compounds. Cannabinoids as a whole are very lipophilic, resulting in decreased bioavailability, which presents challenges in optimal drug delivery. ...This article is …
We describe the absorption, distribution, metabolism, and excretion of each of the above mentioned compounds. Cannabinoids as a whole …
Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities.
Lal S, Shekher A, Puneet, Narula AS, Abrahamse H, Gupta SC. Lal S, et al. Pharmacol Res. 2021 Jan;163:105302. doi: 10.1016/j.phrs.2020.105302. Epub 2020 Nov 24. Pharmacol Res. 2021. PMID: 33246167 Review.
The non-psychoactive cannabidiol (CBD) and the psychoactive delta(9)-tetrahydrocannabinol (delta(9)-THC) are the major and widely studied constituents from this plant. Cannabinoids exert their effects through the endocannabinoid system (ECS) that comprises cannabinoid …
The non-psychoactive cannabidiol (CBD) and the psychoactive delta(9)-tetrahydrocannabinol (delta(9)-THC) are the major and widely studied co …
360 results