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35 results
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Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
Parhiz H, Brenner JS, Patel PN, Papp TE, Shahnawaz H, Li Q, Shi R, Zamora ME, Yadegari A, Marcos-Contreras OA, Natesan A, Pardi N, Shuvaev VV, Kiseleva R, Myerson JW, Uhler T, Riley RS, Han X, Mitchell MJ, Lam K, Heyes J, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: brenner js. J Control Release. 2022 Apr;344:50-61. doi: 10.1016/j.jconrel.2021.12.027. Epub 2021 Dec 23. J Control Release. 2022. PMID: 34953981 Free PMC article.
The Nano-War Against Complement Proteins.
Wang Z, Brenner JS. Wang Z, et al. Among authors: brenner js. AAPS J. 2021 Sep 10;23(5):105. doi: 10.1208/s12248-021-00630-9. AAPS J. 2021. PMID: 34505951 Free PMC article. Review.
Here, we review how complement achieves its blockade of nanomedicine, which nanocarrier materials properties best avoid complement, and current and future strategies to control complement to unleash nanomedicine's potential....
Here, we review how complement achieves its blockade of nanomedicine, which nanocarrier materials properties best avoid complement, and curr …
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
Parhiz H, Shuvaev VV, Pardi N, Khoshnejad M, Kiseleva RY, Brenner JS, Uhler T, Tuyishime S, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: brenner js. J Control Release. 2018 Dec 10;291:106-115. doi: 10.1016/j.jconrel.2018.10.015. Epub 2018 Oct 15. J Control Release. 2018. PMID: 30336167 Free PMC article.
Nanomedicine to fight infectious disease.
Rubey KM, Brenner JS. Rubey KM, et al. Among authors: brenner js. Adv Drug Deliv Rev. 2021 Dec;179:113996. doi: 10.1016/j.addr.2021.113996. Epub 2021 Oct 8. Adv Drug Deliv Rev. 2021. PMID: 34634395 Free PMC article. Review.
Targeting drug delivery in the vascular system: Focus on endothelium.
Glassman PM, Myerson JW, Ferguson LT, Kiseleva RY, Shuvaev VV, Brenner JS, Muzykantov VR. Glassman PM, et al. Among authors: brenner js. Adv Drug Deliv Rev. 2020;157:96-117. doi: 10.1016/j.addr.2020.06.013. Epub 2020 Jun 21. Adv Drug Deliv Rev. 2020. PMID: 32579890 Free PMC article. Review.
Nanoparticle-Induced Augmentation of Neutrophils' Phagocytosis of Bacteria.
Rubey KM, Mukhitov AR, Nong J, Wu J, Krymskaya VP, Myerson JW, Worthen GS, Brenner JS. Rubey KM, et al. Among authors: brenner js. Front Pharmacol. 2022 Jul 4;13:923814. doi: 10.3389/fphar.2022.923814. eCollection 2022. Front Pharmacol. 2022. PMID: 35860017 Free PMC article.
Systems approaches to design of targeted therapeutic delivery.
Myerson JW, Brenner JS, Greineder CF, Muzykantov VR. Myerson JW, et al. Among authors: brenner js. Wiley Interdiscip Rev Syst Biol Med. 2015 Sep-Oct;7(5):253-65. doi: 10.1002/wsbm.1304. Epub 2015 May 6. Wiley Interdiscip Rev Syst Biol Med. 2015. PMID: 25946066 Free PMC article. Review.
Imatinib alleviates lung injury and prolongs survival in ventilated rats.
Xin Y, Cereda M, Yehya N, Humayun S, Delvecchio P, Thompson JM, Martin K, Hamedani H, Martorano P, Duncan I, Kadlecek S, Makvandi M, Brenner JS, Rizi RR. Xin Y, et al. Among authors: brenner js. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L866-L872. doi: 10.1152/ajplung.00006.2022. Epub 2022 Apr 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35438574
35 results