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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1861 1
1873 1
1875 2
1905 1
1907 1
1909 1
1921 1
1923 1
1926 1
1927 1
1931 1
1935 2
1940 1
1941 1
1945 8
1946 14
1947 26
1948 93
1949 75
1950 68
1951 38
1952 13
1953 16
1954 14
1955 19
1956 24
1957 36
1958 29
1959 30
1960 28
1961 32
1962 38
1963 50
1964 80
1965 49
1966 42
1967 71
1968 98
1969 128
1970 152
1971 190
1972 190
1973 138
1974 191
1975 222
1976 213
1977 203
1978 185
1979 196
1980 256
1981 271
1982 309
1983 401
1984 502
1985 594
1986 590
1987 617
1988 656
1989 720
1990 795
1991 822
1992 781
1993 871
1994 930
1995 872
1996 907
1997 921
1998 909
1999 942
2000 969
2001 983
2002 1053
2003 1130
2004 1205
2005 1375
2006 1507
2007 1480
2008 1469
2009 1530
2010 1645
2011 1775
2012 1859
2013 1902
2014 1896
2015 1847
2016 1810
2017 1681
2018 1704
2019 1643
2020 1835
2021 1776
2022 1700
2023 1429
2024 773

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Search Results

49,942 results

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Page 1
Uncaging calcium in neurons.
Delaney KR, Shahrezaei V. Delaney KR, et al. Cold Spring Harb Protoc. 2013 Dec 1;2013(12):1115-24. doi: 10.1101/pdb.top079491. Cold Spring Harb Protoc. 2013. PMID: 24298037 Review.
Changes in intracellular free calcium concentration (delta[Ca(2+)]i) driving physiological events such as neurotransmitter release or Ca(2+)-dependent currents can be monitored using Ca(2+)-sensitive fluorescent dyes. ...Photolabile Ca(2+) chelators are Ca(2+)-binding mole …
Changes in intracellular free calcium concentration (delta[Ca(2+)]i) driving physiological events such as neurotransmitter release or …
Calcium and Calcium Salts.
Trailokya A, Srivastava A, Bhole M, Zalte N. Trailokya A, et al. J Assoc Physicians India. 2017 Feb;65(2):100-103. J Assoc Physicians India. 2017. PMID: 28457049 No abstract available.
Extracellular Calcium Receptor as a Target for Glutathione and Its Derivatives.
Goralski T, Ram JL. Goralski T, et al. Int J Mol Sci. 2022 Jan 10;23(2):717. doi: 10.3390/ijms23020717. Int J Mol Sci. 2022. PMID: 35054903 Free PMC article. Review.
Extracellular glutathione (GSH) and oxidized glutathione (GSSG) can modulate the function of the extracellular calcium sensing receptor (CaSR). The CaSR has a binding pocket in the extracellular domain of CaSR large enough to bind either GSH or GSSG, as well as the natural …
Extracellular glutathione (GSH) and oxidized glutathione (GSSG) can modulate the function of the extracellular calcium sensing recept …
Metallacyclosilanes of Calcium, Yttrium, and Iron.
Pöcheim A, Zitz R, Hönigsberger J, Marschner C, Baumgartner J. Pöcheim A, et al. Inorg Chem. 2022 Nov 7;61(44):17527-17536. doi: 10.1021/acs.inorgchem.2c02508. Epub 2022 Oct 25. Inorg Chem. 2022. PMID: 36281990 Free PMC article.
Utilizing a choice of alpha,omega-oligosilanylene diides, it is possible to synthesize a number of heterocyclosilanes with heteroelements of calcium, yttrium, and iron by metathesis reactions with respective metal halides CaI(2), YCl(3), and FeBr(2). (29)Si NMR spectroscop …
Utilizing a choice of alpha,omega-oligosilanylene diides, it is possible to synthesize a number of heterocyclosilanes with heteroelements of …
An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction.
Gregory CA, Gunn WG, Peister A, Prockop DJ. Gregory CA, et al. Anal Biochem. 2004 Jun 1;329(1):77-84. doi: 10.1016/j.ab.2004.02.002. Anal Biochem. 2004. PMID: 15136169
Alizarin red S (ARS) staining has been used for decades to evaluate calcium-rich deposits by cells in culture. It is particularly versatile in that the dye can be extracted from the stained monolayer and assayed. ...Furthermore, the linear range is much wider than those of …
Alizarin red S (ARS) staining has been used for decades to evaluate calcium-rich deposits by cells in culture. It is particularly ver …
Dithiadiazole derivative 3-(4-nitrophenyl)-5-phenyl-3H-1,2,3,4-dithiadiazole-2-oxide - Novel modulator of store-operated calcium entry.
Grekhnev DA, Novikova IV, Krisanova AV, Yuskovets VN, Chernov NM, Yakovlev IP, Kaznacheyeva EV, Vigont VA. Grekhnev DA, et al. Biochem Biophys Res Commun. 2022 Oct 20;626:38-43. doi: 10.1016/j.bbrc.2022.08.001. Epub 2022 Aug 5. Biochem Biophys Res Commun. 2022. PMID: 35981420
Last decades store-operated calcium channels have been repeatedly postulated as a therapeutic target, so the compounds acting on them can be considered promising drug prototypes. ...Moreover, incubation of the cells with this compound also resulted in the dec …
Last decades store-operated calcium channels have been repeatedly postulated as a therapeutic target, so the compounds acting …
Intracellular calcium and neurotoxic events.
Bondy SC. Bondy SC. Neurotoxicol Teratol. 1989 Nov-Dec;11(6):527-31. doi: 10.1016/0892-0362(89)90032-9. Neurotoxicol Teratol. 1989. PMID: 2696873 Review.
Calcium is important in many intracellular regulatory processes. However, the maintenance of low levels of this cation within the cytosol is essential for maintenance of cell viability, in view of the large concentration gradient of ionic calcium across the plasma m …
Calcium is important in many intracellular regulatory processes. However, the maintenance of low levels of this cation within the cyt …
Changes in calcium's role as a messenger during aging in neuronal and nonneuronal cells.
Peterson C. Peterson C. Ann N Y Acad Sci. 1992 Nov 21;663:279-93. doi: 10.1111/j.1749-6632.1992.tb38671.x. Ann N Y Acad Sci. 1992. PMID: 1482059 Review.
Alterations in calcium transport appear to be functionally significant. Treatment with drugs that promote calcium uptake partially reverse some of the age-related deficits in calcium-dependent processes. ...Depressed cell spreading of fibroblasts can be rever …
Alterations in calcium transport appear to be functionally significant. Treatment with drugs that promote calcium uptake parti …
A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.
Boutin ME, Strong CE, Van Hese B, Hu X, Itkin Z, Chen YC, LaCroix A, Gordon R, Guicherit O, Carromeu C, Kundu S, Lee E, Ferrer M. Boutin ME, et al. SLAS Discov. 2022 Jun;27(4):209-218. doi: 10.1016/j.slasd.2022.01.003. Epub 2022 Jan 31. SLAS Discov. 2022. PMID: 35092840 Free PMC article.
In this report we present a proof-of-concept study evaluating 3D iPSC-derived cortical neural spheroids as a physiologically- and pharmacologically-relevant high-throughput screening (HTS) platform and investigate their potential for use for therapeutic development. To this end, …
In this report we present a proof-of-concept study evaluating 3D iPSC-derived cortical neural spheroids as a physiologically- and pharmacolo …
2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors.
Wang YS, Yeh TK, Chang WC, Liou JP, Liu YM, Huang WC. Wang YS, et al. Eur J Med Chem. 2022 Dec 5;243:114773. doi: 10.1016/j.ejmech.2022.114773. Epub 2022 Sep 17. Eur J Med Chem. 2022. PMID: 36179401
Furthermore, the cell proliferation assay results showed that MPT0M004 (8a) had lower cytotoxicity than 2-APB, the reference compound. In the pharmacokinetic study, MPT0M004 (8a) has a long half-life (T(1/2) = 24 h) and lower daily dose administered intravenously with an o …
Furthermore, the cell proliferation assay results showed that MPT0M004 (8a) had lower cytotoxicity than 2-APB, the reference compound …
49,942 results
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