CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival.
Eesmaa A, Yu LY, Göös H, Danilova T, Nõges K, Pakarinen E, Varjosalo M, Lindahl M, Lindholm P, Saarma M.
Eesmaa A, et al.
Int J Mol Sci. 2022 Aug 22;23(16):9489. doi: 10.3390/ijms23169489.
Int J Mol Sci. 2022.
PMID: 36012764
Free PMC article.
We used tunicamycin to induce ER stress in mice in vivo and used cultured primary neurons and found that CDNF expression is regulated by ER stress in vivo and that the involvement of UPR pathways is important for the neuroprotective function of CDNF. Moreover, we us …
We used tunicamycin to induce ER stress in mice in vivo and used cultured primary neurons and found that CDNF expression is regulated …