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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1918 2
1923 3
1924 1
1926 1
1927 2
1928 2
1929 1
1930 2
1932 2
1933 3
1934 2
1936 2
1937 1
1938 1
1939 2
1940 1
1941 3
1943 1
1945 10
1946 57
1947 31
1948 63
1949 47
1950 89
1951 75
1952 60
1953 72
1954 86
1955 93
1956 93
1957 97
1958 115
1959 130
1960 213
1961 332
1962 423
1963 575
1964 1056
1965 827
1966 757
1967 1332
1968 2004
1969 2371
1970 2623
1971 3202
1972 3511
1973 3507
1974 4189
1975 4344
1976 4096
1977 4315
1978 5277
1979 5676
1980 6217
1981 6989
1982 8252
1983 9320
1984 10118
1985 10682
1986 11812
1987 14100
1988 16204
1989 19750
1990 23722
1991 26462
1992 29099
1993 31681
1994 34883
1995 38402
1996 40814
1997 43842
1998 48306
1999 52217
2000 57684
2001 60683
2002 61949
2003 66165
2004 70935
2005 75563
2006 80773
2007 83534
2008 87030
2009 91526
2010 97862
2011 104622
2012 109747
2013 114234
2014 116282
2015 118908
2016 116424
2017 117044
2018 117357
2019 121564
2020 129549
2021 132578
2022 122402
2023 111550
2024 46485

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2,692,307 results

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Page 1
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers.
Dufva O, Gandolfi S, Huuhtanen J, Dashevsky O, Duàn H, Saeed K, Klievink J, Nygren P, Bouhlal J, Lahtela J, Näätänen A, Ghimire BR, Hannunen T, Ellonen P, Lähteenmäki H, Rumm P, Theodoropoulos J, Laajala E, Härkönen J, Pölönen P, Heinäniemi M, Hollmén M, Yamano S, Shirasaki R, Barbie DA, Roth JA, Romee R, Sheffer M, Lähdesmäki H, Lee DA, De Matos Simoes R, Kankainen M, Mitsiades CS, Mustjoki S. Dufva O, et al. Immunity. 2023 Dec 12;56(12):2816-2835.e13. doi: 10.1016/j.immuni.2023.11.008. Immunity. 2023. PMID: 38091953 Free article.
Cancer cells can evade natural killer (NK) cell activity, thereby limiting anti-tumor immunity. To reveal genetic determinants of susceptibility to NK cell activity, we examined interacting NK cells and blood cancer cells using single- …
Cancer cells can evade natural killer (NK) cell activity, thereby limiting anti-tumor immunity. To reveal genetic deter …
Evolutionary cell type mapping with single-cell genomics.
Tanay A, Sebé-Pedrós A. Tanay A, et al. Trends Genet. 2021 Oct;37(10):919-932. doi: 10.1016/j.tig.2021.04.008. Epub 2021 May 18. Trends Genet. 2021. PMID: 34020820 Review.
Single-cell genomics is emerging as a powerful tool to build comprehensive catalogs of cell types and their associated gene regulatory programs in non-traditional model species. We review the current state of sampling efforts across the animal tree of life and chall …
Single-cell genomics is emerging as a powerful tool to build comprehensive catalogs of cell types and their associated gene re …
Transcriptional Control of Developmental Cell Behaviors.
Bernadskaya Y, Christiaen L. Bernadskaya Y, et al. Annu Rev Cell Dev Biol. 2016 Oct 6;32:77-101. doi: 10.1146/annurev-cellbio-111315-125218. Epub 2016 Aug 8. Annu Rev Cell Dev Biol. 2016. PMID: 27501446 Review.
Cell behaviors classically range from mesenchymal cell motility to cell shape changes in epithelial sheets. These behaviors emerge from the tissue-specific, multiscale integration of the local activities of universal and pleiotropic effectors, which underlie …
Cell behaviors classically range from mesenchymal cell motility to cell shape changes in epithelial sheets. These behav …
The promise of single-cell genomics in plants.
McFaline-Figueroa JL, Trapnell C, Cuperus JT. McFaline-Figueroa JL, et al. Curr Opin Plant Biol. 2020 Apr;54:114-121. doi: 10.1016/j.pbi.2020.04.002. Epub 2020 May 5. Curr Opin Plant Biol. 2020. PMID: 32388018 Free PMC article. Review.
Single-cell genomic approaches have the potential to revolutionize the study of plant systems. ...Lastly, we discuss the inherent limitations of single-cell studies and address future directions for plant single-cell genomics....
Single-cell genomic approaches have the potential to revolutionize the study of plant systems. ...Lastly, we discuss the inherent lim …
New epigenetic regulators of T cell exhaustion.
Kissick H, Ahmed R. Kissick H, et al. Cancer Cell. 2022 Jul 11;40(7):708-710. doi: 10.1016/j.ccell.2022.06.008. Cancer Cell. 2022. PMID: 35820395 Free article.
In this issue of Cancer Cell, Belk et al. perform an in vitro CRISPR screen to identify genes that regulate CD8(+) T cell exhaustion. They find several genes related to epigenetic modification and show that by eliminating Arid1a, CD8(+) T cells retain prolife …
In this issue of Cancer Cell, Belk et al. perform an in vitro CRISPR screen to identify genes that regulate CD8(+) T cell exha …
Mapping Human Reproduction with Single-Cell Genomics.
Marečková M, Massalha H, Lorenzi V, Vento-Tormo R. Marečková M, et al. Annu Rev Genomics Hum Genet. 2022 Aug 31;23:523-547. doi: 10.1146/annurev-genom-120121-114415. Epub 2022 May 13. Annu Rev Genomics Hum Genet. 2022. PMID: 35567278 Free article. Review.
The trillions of cells in the human body develop as a result of the fusion of two extremely specialized cells: an oocyte and a sperm. This process is essential for the continuation of our species, as it ensures that parental genetic information is mixed and p …
The trillions of cells in the human body develop as a result of the fusion of two extremely specialized cells: an oocyte and a …
The Genomics and Cell Biology of Host-Beneficial Intracellular Infections.
McCutcheon JP. McCutcheon JP. Annu Rev Cell Dev Biol. 2021 Oct 6;37:115-142. doi: 10.1146/annurev-cellbio-120219-024122. Epub 2021 Jul 9. Annu Rev Cell Dev Biol. 2021. PMID: 34242059 Review.
Microbes gain access to eukaryotic cells as food for bacteria-grazing protists, for host protection by microbe-killing immune cells, or for microbial benefit when pathogens enter host cells to replicate. ...The genomes of host-beneficial intracellular bacteri …
Microbes gain access to eukaryotic cells as food for bacteria-grazing protists, for host protection by microbe-killing immune cell …
Single-cell genomics.
Lange BM. Lange BM. Curr Opin Plant Biol. 2005 Jun;8(3):236-41. doi: 10.1016/j.pbi.2005.03.015. Curr Opin Plant Biol. 2005. PMID: 15860419 Review.
The evolution of higher plants depended on the ability of cells to express hereditary information in many different ways and led to the development of specialized cell types, reflecting an elaborate system of control over gene expression in the individual component …
The evolution of higher plants depended on the ability of cells to express hereditary information in many different ways and led to t …
Applying single-cell highly multiplexed secretome proteomics to characterize immunotherapeutic products and predict clinical responses.
Ni W, Han EX, Cyr M, Mackay S, Zhou J. Ni W, et al. Proteomics. 2023 Jul;23(13-14):e2200242. doi: 10.1002/pmic.202200242. Epub 2023 Feb 25. Proteomics. 2023. PMID: 36786585 Review.
Genetically and phenotypically identical immune cell populations can be highly heterogenous in terms of their immune functions and protein secretion profiles. ...Increasing evidence has demonstrated that polyfunctional T cells that simultaneously produce 2+ p …
Genetically and phenotypically identical immune cell populations can be highly heterogenous in terms of their immune functions …
Thomas A. Richards.
Richards TA. Richards TA. Curr Biol. 2023 Apr 10;33(7):R247-R248. doi: 10.1016/j.cub.2023.03.001. Curr Biol. 2023. PMID: 37040700 Free article.
Interview with Tom Richards, who uses comparative genomics and molecular biology to explore eukaryotic cell evolution....
Interview with Tom Richards, who uses comparative genomics and molecular biology to explore eukaryotic cell evolution....
2,692,307 results
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