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Centella asiatica alleviates psoriasis through JAK/STAT3-mediated inflammation: An in vitro and in vivo study.
Lin P, Shi HY, Lu YY, Lin J. Lin P, et al. J Ethnopharmacol. 2023 Dec 5;317:116746. doi: 10.1016/j.jep.2023.116746. Epub 2023 Jun 8. J Ethnopharmacol. 2023. PMID: 37295572
CONCLUSION: Centella asiatica extracts were effective in improving skin inflammation and skin barrier dysfunction, and also alleviated psoriasis through JAK/STAT3 pathway. The results provided experimental support for the potential use of Centella asiatica in …
CONCLUSION: Centella asiatica extracts were effective in improving skin inflammation and skin barrier dysfunction, and also al …
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.
Lee Y, Choi HK, N'deh KPU, Choi YJ, Fan M, Kim EK, Chung KH, An AJH. Lee Y, et al. Nutrients. 2020 Feb 5;12(2):411. doi: 10.3390/nu12020411. Nutrients. 2020. PMID: 32033291 Free PMC article.
This study explored the anti-inflammatory and immunomodulatory effects of the Centella asiatica ethanol extract (CA) on an AD-like dermal disorder. ...Collectively, our data demonstrate the pharmacological role and signaling mechanism of CA in the regulation of allergic …
This study explored the anti-inflammatory and immunomodulatory effects of the Centella asiatica ethanol extract (CA) on an AD-like de …
Protective effects of Centella asiatica extract on spatial memory and learning deficits in animal model of systemic inflammation induced by lipopolysaccharide.
Md Pisar M, Chee BJ, Long I, Osman A. Md Pisar M, et al. Ann Med. 2023 Dec;55(1):2224970. doi: 10.1080/07853890.2023.2224970. Ann Med. 2023. PMID: 37318144 Free PMC article.
The present study was designed to investigate the effect of Centella asiatica (CA) extract on inflammatory responses induced by lipopolysaccharide (LPS) and resulting changes in cognitive behavior. ...Pathologically, neither gross abnormalities nor histopathological change …
The present study was designed to investigate the effect of Centella asiatica (CA) extract on inflammatory responses induced by lipop …
Centella asiatica extract protects against cisplatin-induced hepatotoxicity via targeting oxidative stress, inflammation, and apoptosis.
Ferah Okkay I, Okkay U, Aydin IC, Bayram C, Ertugrul MS, Mendil AS, Hacimuftuoglu A. Ferah Okkay I, et al. Environ Sci Pollut Res Int. 2022 May;29(22):33774-33784. doi: 10.1007/s11356-022-18626-z. Epub 2022 Jan 14. Environ Sci Pollut Res Int. 2022. PMID: 35029831
This study was designed to investigate the protective effects of Centella asiatica (CA) on cisplatin-induced hepatotoxicity and to clarify the underlying mechanism by biochemical, molecular, immunohistochemical, and histopathological analyses. ...
This study was designed to investigate the protective effects of Centella asiatica (CA) on cisplatin-induced hepatotoxicity and to cl …
Centella asiatica (L.) extract attenuates inflammation and improve insulin sensitivity in a coculture of lipopolysaccharide (LPS)-induced 3T3-L1 adipocytes and RAW 264.7 macrophages.
Kusumastuti SA, Nugrahaningsih DAA, Wahyuningsih MSH. Kusumastuti SA, et al. Drug Discov Ther. 2019;13(5):261-267. doi: 10.5582/ddt.2019.01052. Drug Discov Ther. 2019. PMID: 31723097 Free article.
Insulin resistance in obese condition is related to chronic low-grade inflammation which leads to insulin signaling impairment. Centella asiatica (L.) is an herb that exhibits anti-inflammatory and blood sugar-lowering activity (hypoglycemia). ...These findings sugg …
Insulin resistance in obese condition is related to chronic low-grade inflammation which leads to insulin signaling impairment. Ce
Centella asiatica Extract Attenuates Kidney Fibrosis Through Reducing Mesenchymal Transition and Inflammation in Ureteral Ligation Model in Mice.
Sari DCR, Budiharjo S, Afifah H, Jasmin D, Kokasih O, Putri TG, Arifiani K, Setyaningsih WAW, Arfian N. Sari DCR, et al. Front Pharmacol. 2021 Mar 17;12:621894. doi: 10.3389/fphar.2021.621894. eCollection 2021. Front Pharmacol. 2021. PMID: 33815106 Free PMC article.
Centella asiatia (CeA) is an herb that has a reno-protective effect. ...Conclusion: CeA treatment with dose-dependently ameliorates mesenchymal transition and inflammation in kidney fibrosis in mice....
Centella asiatia (CeA) is an herb that has a reno-protective effect. ...Conclusion: CeA treatment with dose-dependently ameliorates m
A review of pharmacokinetic and pharmacological properties of asiaticoside, a major active constituent of Centella asiatica (L.) Urb.
He Z, Hu Y, Niu Z, Zhong K, Liu T, Yang M, Ji L, Hu W. He Z, et al. J Ethnopharmacol. 2023 Feb 10;302(Pt A):115865. doi: 10.1016/j.jep.2022.115865. Epub 2022 Oct 25. J Ethnopharmacol. 2023. PMID: 36306932 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Centella asiatica (L.) Urb., a potential medicinal plant, is widely used in orient traditional medicine. ...It has a variety of pharmacological effects including anti-neural inflammation and anti-cancer properties, as well as protecti …
ETHNOPHARMACOLOGICAL RELEVANCE: Centella asiatica (L.) Urb., a potential medicinal plant, is widely used in orient traditional medici …
Centella asiatica promotes antioxidant gene expression and mitochondrial oxidative respiration in experimental autoimmune encephalomyelitis.
Kundu P, Yasuhara K, Brandes MS, Zweig JA, Neff CJ, Holden S, Kessler K, Matsumoto S, Offner H, Waslo CS, Vandenbark A, Soumyanath A, Sherman LS, Raber J, Gray NE, Spain RI. Kundu P, et al. Res Sq [Preprint]. 2023 Oct 6:rs.3.rs-3393042. doi: 10.21203/rs.3.rs-3393042/v1. Res Sq. 2023. PMID: 37886497 Free PMC article. Preprint.
Centella asiatica (Centella) is a traditional botanical medicine that shows promise in treating dementia based on behavioral alterations seen in animal models of aging and cognitive dysfunction. In order to determine if Centella could similarly improve cognit
Centella asiatica (Centella) is a traditional botanical medicine that shows promise in treating dementia based on behavioral a
Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency.
Lichota A, Gwozdzinski L, Gwozdzinski K. Lichota A, et al. Eur J Med Chem. 2019 Aug 15;176:68-91. doi: 10.1016/j.ejmech.2019.04.075. Epub 2019 May 6. Eur J Med Chem. 2019. PMID: 31096120 Review.
It is, however, based on hypotensive blood vessels, hypoxia, and other mechanisms associated with inflammation. This work describes mechanisms related to the formation and development of the varicose vein. It discusses risk factors, pathogenesis of chronic venous disease, …
It is, however, based on hypotensive blood vessels, hypoxia, and other mechanisms associated with inflammation. This work describes m …
Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort.
Herrera-Hidalgo L, Muñoz P, Álvarez-Uría A, Alonso-Menchén D, Luque-Marquez R, Gutiérrez-Carretero E, Fariñas MDC, Miró JM, Goenaga MA, López-Cortés LE, Angulo-Lara B, Boix-Palop L, de Alarcón A; Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES) Cohort Investigators. Herrera-Hidalgo L, et al. Int J Infect Dis. 2023 Dec;137:134-143. doi: 10.1016/j.ijid.2023.10.019. Epub 2023 Nov 4. Int J Infect Dis. 2023. PMID: 37926195 Free article.
123 results