Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1966 1
1967 2
1968 1
1969 2
1970 5
1971 5
1972 1
1973 6
1974 7
1975 14
1976 7
1977 15
1978 9
1979 18
1980 14
1981 24
1982 26
1983 42
1984 48
1985 34
1986 36
1987 47
1988 53
1989 48
1990 58
1991 45
1992 53
1993 46
1994 46
1995 37
1996 51
1997 49
1998 55
1999 59
2000 54
2001 53
2002 57
2003 57
2004 64
2005 71
2006 77
2007 87
2008 90
2009 74
2010 89
2011 95
2012 116
2013 109
2014 142
2015 148
2016 158
2017 159
2018 164
2019 178
2020 180
2021 219
2022 276
2023 221
2024 96

Text availability

Article attribute

Article type

Publication date

Search Results

3,694 results

Results by year

Filters applied: . Clear all
Page 1
Classifying cephalosporins: from generation to cross-reactivity.
Fernandez J, Jimenez-Rodriguez TW, Blanca-Lopez N. Fernandez J, et al. Curr Opin Allergy Clin Immunol. 2021 Aug 1;21(4):346-354. doi: 10.1097/ACI.0000000000000755. Curr Opin Allergy Clin Immunol. 2021. PMID: 34074874 Review.
PURPOSE OF REVIEW: To review the most recent literature studying the classifications, immunochemistry, and crossreactivity of allergy reactions to cephalosporins. RECENT FINDINGS: Over the last five years, research interest has focused on three areas related to cephalos
PURPOSE OF REVIEW: To review the most recent literature studying the classifications, immunochemistry, and crossreactivity of allergy reacti …
Cephalosporin Allergy: Current Understanding and Future Challenges.
Khan DA, Banerji A, Bernstein JA, Bilgicer B, Blumenthal K, Castells M, Ein D, Lang DM, Phillips E. Khan DA, et al. J Allergy Clin Immunol Pract. 2019 Sep-Oct;7(7):2105-2114. doi: 10.1016/j.jaip.2019.06.001. J Allergy Clin Immunol Pract. 2019. PMID: 31495420 Free PMC article. Review.
Hypersensitivity reactions to cephalosporins are becoming increasingly common with a wide range of immunopathologic mechanisms. ...Patients allergic to cephalosporins tend to tolerate cephalosporins with disparate R1 side chains but may react to other …
Hypersensitivity reactions to cephalosporins are becoming increasingly common with a wide range of immunopathologic mechanisms
New Perspectives on Antimicrobial Agents: Cefiderocol.
McCreary EK, Heil EL, Tamma PD. McCreary EK, et al. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0217120. doi: 10.1128/AAC.02171-20. Epub 2021 Jul 16. Antimicrob Agents Chemother. 2021. PMID: 34031052 Free PMC article. Review.
No available agent comes close to the broad range of activity afforded by cefiderocol, a novel siderophore-cephalosporin conjugate. The novelty of and need for cefiderocol are clear, but available clinical data are conflicting, leaving infectious diseases specialists puzzl …
No available agent comes close to the broad range of activity afforded by cefiderocol, a novel siderophore-cephalosporin conjugate. T …
Mechanism of action of cefiderocol.
Soriano A, Mensa J. Soriano A, et al. Rev Esp Quimioter. 2022 Sep;35 Suppl 2(Suppl 2):16-19. doi: 10.37201/req/s02.02.2022. Epub 2022 Oct 4. Rev Esp Quimioter. 2022. PMID: 36193980 Free PMC article. Review.
In 2017 and 2019, the World Health Organization published a list of urgent threats and priorities in the context of drug resistance, which only included Gram-negative bacteria and specially focused on carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa, as wel …
In 2017 and 2019, the World Health Organization published a list of urgent threats and priorities in the context of drug resistance, which o …
Cephalosporins as key lead generation beta-lactam antibiotics.
Lin X, Kück U. Lin X, et al. Appl Microbiol Biotechnol. 2022 Dec;106(24):8007-8020. doi: 10.1007/s00253-022-12272-8. Appl Microbiol Biotechnol. 2022. PMID: 36401643 Free PMC article. Review.
CPC serves as a core compound for producing semi-synthetic cephalosporins that can control infections with different resistance mechanisms. ...Finally, we describe how CPC serves as a key lead generation source for the in vitro and better, in vivo synthesis of 7-ami …
CPC serves as a core compound for producing semi-synthetic cephalosporins that can control infections with different resistance me
[Penicillin allergy].
Ortega-Cisneros M, Moras-Villela VL, Delgado-Bañuelos A, Madrigal-Beas IM, Aguilar-Chávez Y, Ochoa-García IV, Chávez-Meléndez MÁ, Gómez-Hernández N. Ortega-Cisneros M, et al. Rev Alerg Mex. 2022;69 Suppl 1:s81-s93. doi: 10.29262/ram.v69iSup1.1038. Rev Alerg Mex. 2022. PMID: 34998313 Spanish.
Cross reaction is reported in 2 to 5 % between penicillins and cephalosporin. There is no cross reaction between penicillins and aztreonam, but there is with ceftazidime. All the mechanisms of the Gell and Coombs classification are included in the pathophysiology of …
Cross reaction is reported in 2 to 5 % between penicillins and cephalosporin. There is no cross reaction between penicillins and aztr …
Aspects of the mechanism of action of some cephalosporins.
Russell AD, Fountain RH. Russell AD, et al. J Bacteriol. 1971 Apr;106(1):65-9. doi: 10.1128/jb.106.1.65-69.1971. J Bacteriol. 1971. PMID: 4928017 Free PMC article.
Cephaloridine and cephalexin had no effect on ribonucleic acid (RNA), deoxyribonucleic acid (DNA), or protein synthesis in Escherichia coli. However, cephalosporin 7/30 [7-(S-benzylthioacetamido)-cephem-3-ylmethyl-N -dimethyldithiocarbamate-4-carboxylic acid] and dimethyld …
Cephaloridine and cephalexin had no effect on ribonucleic acid (RNA), deoxyribonucleic acid (DNA), or protein synthesis in Escherichia coli. …
Potential Application of Cephalosporins Carried in Organic or Inorganic Nanosystems against Gram-Negative Pathogens.
Bezerra BMS, Dantas de Mendonça Y Araujo SE, Cordeiro de Macêdo A, Costa KMN, Sato MR, Oshiro-Junior JA. Bezerra BMS, et al. Curr Med Chem. 2022 Aug 15;29(31):5212-5229. doi: 10.2174/0929867329666220329201817. Curr Med Chem. 2022. PMID: 35352643 Review.
Commercially, conventional pharmaceutical forms require high doses to ensure clinical efficacy. Additionally, beta-lactam resistance mechanisms, such as the production of enzymes (called extended-spectrum beta-lactamases) and the low plasma half-life of these antibiotics, …
Commercially, conventional pharmaceutical forms require high doses to ensure clinical efficacy. Additionally, beta-lactam resistance mech
Third-generation cephalosporins: a critical evaluation.
Barriere SL, Flaherty JF. Barriere SL, et al. Clin Pharm. 1984 Jul-Aug;3(4):351-73. Clin Pharm. 1984. PMID: 6432420 Review.
Six third-generation cephalosporins--cefotaxime, moxalactam, cefoperazone, ceftizoxime, ceftriaxone, and cefmenoxime--are reviewed; covered are chemistry and structure-activity relationships, mechanism of action, spectra of activity, pharmacokinetics, clinical utili …
Six third-generation cephalosporins--cefotaxime, moxalactam, cefoperazone, ceftizoxime, ceftriaxone, and cefmenoxime--are reviewed; c …
Antibacterial spectrum of cefiderocol.
Gijón Cordero D, Castillo-Polo JA, Ruiz-Garbajosa P, Cantón R. Gijón Cordero D, et al. Rev Esp Quimioter. 2022 Sep;35 Suppl 2(Suppl 2):20-27. doi: 10.37201/req/s02.03.2022. Epub 2022 Oct 4. Rev Esp Quimioter. 2022. PMID: 36193981 Free PMC article. Review.
Cefiderocol, a siderophore catechol cephalosporin, recently introduced in the market has been developed to enhance the in vitro activity of extended spectrum cephalosporins and to avoid resistance mechanisms affecting cephalosporins and carbapenems. .. …
Cefiderocol, a siderophore catechol cephalosporin, recently introduced in the market has been developed to enhance the in vitro activ …
3,694 results