Cocaine and its metabolites constrict cerebral arterioles in newborn pigs.
Kurth CD, Monitto C, Albuquerque ML, Feuer P, Anday E, Shaw L.
Kurth CD, et al.
J Pharmacol Exp Ther. 1993 May;265(2):587-91.
J Pharmacol Exp Ther. 1993.
PMID: 8496809
Cerebral vasoconstriction induced by topically applied norepinephrine was enhanced by cocaine, norcocaine and cocaethylene, but not by the other three metabolites. Topical application of phentolamine failed to block vasoconstriction elicited by coca …
Cerebral vasoconstriction induced by topically applied norepinephrine was enhanced by cocaine, norcocaine and cocaethylene, bu …