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1970 1
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2002 2
2003 5
2004 6
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2007 7
2008 14
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397 results

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Page 1
Cuproptosis illustrates tumor micro-environment features and predicts prostate cancer therapeutic sensitivity and prognosis.
Cheng B, Tang C, Xie J, Zhou Q, Luo T, Wang Q, Huang H. Cheng B, et al. Life Sci. 2023 Jul 15;325:121659. doi: 10.1016/j.lfs.2023.121659. Epub 2023 Apr 1. Life Sci. 2023. PMID: 37011878
Cuproptosis, a copper-dependent programmed cell death mechanism, plays a vital role in tumor development, therapy resistance, and immune microenvironment regulation in PCA. ...PDHA1 can be regarded as an important target for PCA therapy....
Cuproptosis, a copper-dependent programmed cell death mechanism, plays a vital role in tumor development, therapy resistance, and imm …
A novel signature to guide osteosarcoma prognosis and immune microenvironment: Cuproptosis-related lncRNA.
Yang M, Zheng H, Xu K, Yuan Q, Aihaiti Y, Cai Y, Xu P. Yang M, et al. Front Immunol. 2022 Jul 29;13:919231. doi: 10.3389/fimmu.2022.919231. eCollection 2022. Front Immunol. 2022. PMID: 35967366 Free PMC article.
Risk curve, survival, receiver operating characteristic (ROC) curve, and independent prognostic analyses were performed. Next, principal component analysis (PCA) and t-distributed stochastic neighbor embedding (t-SNE) analysis were performed. ...
Risk curve, survival, receiver operating characteristic (ROC) curve, and independent prognostic analyses were performed. Next, principal com …
Copper, PET/CT and prostate cancer: a systematic review of the literature.
Piccardo A, Ugolini M, Righi S, Bottoni G, Cistaro A, Paparo F, Giovanella L, Evangelista L. Piccardo A, et al. Q J Nucl Med Mol Imaging. 2020 Dec;64(4):382-392. doi: 10.23736/S1824-4785.20.03277-X. Epub 2020 Sep 9. Q J Nucl Med Mol Imaging. 2020. PMID: 32900177 Review.
Copper is an essential element that plays an important role in both cancer development and growth. Indeed, high levels of copper have been found in prostate cancer (PCa), and this finding have paved the way for the use of this element as a target for positron
Copper is an essential element that plays an important role in both cancer development and growth. Indeed, high levels of copper
EREG is the core onco-immunological biomarker of cuproptosis and mediates the cross-talk between VEGF and CD99 signaling in glioblastoma.
Zhou Y, Xiao D, Jiang X, Nie C. Zhou Y, et al. J Transl Med. 2023 Jan 16;21(1):28. doi: 10.1186/s12967-023-03883-4. J Transl Med. 2023. PMID: 36647156 Free PMC article.
Glioblastoma multiforme (GBM) is the most malignant form of glioma with an extremely poor prognosis. A novel, regulated cell death form of copper-induced cell death called "cuproptosis" provides a new prospect for cancer treatment by regulating cuproptosis. ...Epiregulin ( …
Glioblastoma multiforme (GBM) is the most malignant form of glioma with an extremely poor prognosis. A novel, regulated cell death form of …
Copper-inducible expression system for metabolic engineering of Escherichia coli.
Liu L, Zhang L, Wang J, Cao M, Yuan J. Liu L, et al. J Appl Microbiol. 2023 Jun 1;134(6):lxad109. doi: 10.1093/jambio/lxad109. J Appl Microbiol. 2023. PMID: 37230951
By integrating the gene encoding T7 RNAP at the CusC locus, we managed to program eGFP expression under the T7 promoter in response to different concentrations of Cu2+ (0-20 muM). Subsequently, we demonstrated that the copper-inducible expression system was suitable for th …
By integrating the gene encoding T7 RNAP at the CusC locus, we managed to program eGFP expression under the T7 promoter in response to diffe …
Identification of cuproptosis-related genes for predicting the development of prostate cancer.
Wang X, Chen X, Xu C, Zhou W, Wu D. Wang X, et al. Open Med (Wars). 2023 Sep 6;18(1):20230717. doi: 10.1515/med-2023-0717. eCollection 2023. Open Med (Wars). 2023. PMID: 37711156 Free PMC article.
Copper can be toxic at very high intracellular concentrations and can inhibit prostate cancer (PCa) progression. ...The expression of LIAS, LIPT1, DLAT, and PDHB did not alter upon the incidence of PCa in Chinese patients. A constructed regression model showe
Copper can be toxic at very high intracellular concentrations and can inhibit prostate cancer (PCa) progression. ...The expres
Determination of copper status by five biomarkers in serum of healthy women.
Chillon TS, Tuchtenhagen M, Schwarz M, Hackler J, Heller R, Kaghazian P, Moghaddam A, Schomburg L, Haase H, Kipp AP, Schwerdtle T, Maares M. Chillon TS, et al. J Trace Elem Med Biol. 2024 Mar 22;84:127441. doi: 10.1016/j.jtemb.2024.127441. Online ahead of print. J Trace Elem Med Biol. 2024. PMID: 38579499 Free article.
The correlation and Principal Component Analyses (PCA) indicated that CP, CPO activity and total copper correlated well, followed by CuEXC, while the labile copper pool was unrelated to the other parameters. CONCLUSIONS: This study suggests that the non-CP-bo …
The correlation and Principal Component Analyses (PCA) indicated that CP, CPO activity and total copper correlated well, follo …
Biocompatible and biodegradable copper-protocatechuic metal-organic frameworks as rifampicin carrier.
Angkawijaya AE, Bundjaja V, Santoso SP, Go AW, Lin SP, Cheng KC, Soetaredjo FE, Ismadji S. Angkawijaya AE, et al. Biomater Adv. 2023 Mar;146:213269. doi: 10.1016/j.bioadv.2022.213269. Epub 2022 Dec 22. Biomater Adv. 2023. PMID: 36696782
For this reason, biomolecule metal-organic framework (BioMOF) with good biocompatibility, nontoxicity, bioactivity, and high stability are becoming potential drug carriers. This study used a bioactive protocatechuic acid (PCA) as organic linker to prepare copper-bas …
For this reason, biomolecule metal-organic framework (BioMOF) with good biocompatibility, nontoxicity, bioactivity, and high stability are b …
Preparation of Ultra-Small Copper Nanoparticles-Loaded Self-Healing Hydrogels with Antibacterial, Inflammation-Suppressing and Angiogenesis-Enhancing Properties for Promoting Diabetic Wound Healing.
Geng X, Liu K, Wang J, Su X, Shi Y, Zhao L. Geng X, et al. Int J Nanomedicine. 2023 Jun 19;18:3339-3358. doi: 10.2147/IJN.S399933. eCollection 2023. Int J Nanomedicine. 2023. PMID: 37361387 Free PMC article.
CMCS was chemically conjugated to PCA to form self-healing hydrogels via the formation of an amide bond followed by the loading of ultra-small copper nanoparticles. ...It exhibited good biocompatibility in diabetic wounds. Furthermore, Cunps@CMCS-PCA hydrogel …
CMCS was chemically conjugated to PCA to form self-healing hydrogels via the formation of an amide bond followed by the loading of ul …
Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer.
Pinto CIG, Bucar S, Alves V, Fonseca A, Abrunhosa AJ, da Silva CL, Guerreiro JF, Mendes F. Pinto CIG, et al. Front Mol Biosci. 2020 Dec 1;7:609172. doi: 10.3389/fmolb.2020.609172. eCollection 2020. Front Mol Biosci. 2020. PMID: 33335914 Free PMC article.
Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. ...We have previously demonstrated, using monolayer-cultured cells, that copper-64 chloride, a promising theranostic agent for PCa
Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. ...W …
397 results