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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2020 57
2021 150
2022 183
2023 133
2024 47

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513 results

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Clinical Approach to Post-acute Sequelae After COVID-19 Infection and Vaccination.
Hulscher N, Procter BC, Wynn C, McCullough PA. Hulscher N, et al. Cureus. 2023 Nov 21;15(11):e49204. doi: 10.7759/cureus.49204. eCollection 2023 Nov. Cureus. 2023. PMID: 38024037 Free PMC article. Review.
The spike protein of SARS-CoV-2 has been found to exhibit pathogenic characteristics and be a possible cause of post-acute sequelae after SARS-CoV-2 infection or COVID-19 vaccination. COVID-19 vaccines utilize a modified, stabilized prefusion sp …
The spike protein of SARS-CoV-2 has been found to exhibit pathogenic characteristics and be a possible cause of post-acute sequelae after SA …
COVID-19 mRNA vaccines: Platforms and current developments.
Szabó GT, Mahiny AJ, Vlatkovic I. Szabó GT, et al. Mol Ther. 2022 May 4;30(5):1850-1868. doi: 10.1016/j.ymthe.2022.02.016. Epub 2022 Feb 19. Mol Ther. 2022. PMID: 35189345 Free PMC article. Review.
This research uncovered the unique favorable characteristics of mRNA vaccines, including their ability to give rise to non-toxic, potent immune responses and the potential to design and upscale them rapidly, making them excellent vaccine candidates during the corona …
This research uncovered the unique favorable characteristics of mRNA vaccines, including their ability to give rise to non-toxic …
Strategies to reduce the risks of mRNA drug and vaccine toxicity.
Bitounis D, Jacquinet E, Rogers MA, Amiji MM. Bitounis D, et al. Nat Rev Drug Discov. 2024 Apr;23(4):281-300. doi: 10.1038/s41573-023-00859-3. Epub 2024 Jan 23. Nat Rev Drug Discov. 2024. PMID: 38263456 Review.
mRNA formulated with lipid nanoparticles is a transformative technology that has enabled the rapid development and administration of billions of coronavirus disease 2019 (COVID-19) vaccine doses worldwide. However, avoiding unacceptable toxicity with m …
mRNA formulated with lipid nanoparticles is a transformative technology that has enabled the rapid development and administration of billion …
mRNA: Vaccine or Gene Therapy? The Safety Regulatory Issues.
Banoun H. Banoun H. Int J Mol Sci. 2023 Jun 22;24(13):10514. doi: 10.3390/ijms241310514. Int J Mol Sci. 2023. PMID: 37445690 Free PMC article. Review.
COVID-19 vaccines were developed and approved rapidly in response to the urgency created by the pandemic. ...Now that the pandemic emergency has passed, it is time to consider the safety issues associated with this rapid approval. The mode of action of COV …
COVID-19 vaccines were developed and approved rapidly in response to the urgency created by the pandemic. ...Now that t …
Preclinical Toxicity and Immunogenicity of a COVID-19 Vaccine (ZF2001) in Cynomolgus Monkeys.
Yang H, Pan W, Chen G, Huang E, Lu Q, Chen Y, Chen Y, Yang Z, Wen L, Zhang S, Xu C, Lv W, Dai L, Wu C, Zhang L. Yang H, et al. Vaccines (Basel). 2022 Dec 5;10(12):2080. doi: 10.3390/vaccines10122080. Vaccines (Basel). 2022. PMID: 36560490 Free PMC article.
Although the new coronavirus disease 2019 (COVID-19) outbreak occurred in late 2019, it is still endemic worldwide, and has become a global public health problem. Vaccination against SARS-CoV-2 is considered to be the most effective intervention to prevent the sprea …
Although the new coronavirus disease 2019 (COVID-19) outbreak occurred in late 2019, it is still endemic worldwide, and has be …
Autopsy Histopathologic Cardiac Findings in 2 Adolescents Following the Second COVID-19 Vaccine Dose.
Gill JR, Tashjian R, Duncanson E. Gill JR, et al. Arch Pathol Lab Med. 2022 Aug 1;146(8):925-929. doi: 10.5858/arpa.2021-0435-SA. Arch Pathol Lab Med. 2022. PMID: 35157759 Free article.
.-: Myocarditis in adolescents has been diagnosed clinically following the administration of the second dose of an mRNA vaccine for coronavirus disease 2019 (COVID-19). OBJECTIVE.-: To examine the autopsy microscopic cardiac findings in adolescent deaths that occurr …
.-: Myocarditis in adolescents has been diagnosed clinically following the administration of the second dose of an mRNA vaccine for coronavi …
Lipid Nanoparticle-mRNA Formulations for Therapeutic Applications.
Wang C, Zhang Y, Dong Y. Wang C, et al. Acc Chem Res. 2021 Dec 7;54(23):4283-4293. doi: 10.1021/acs.accounts.1c00550. Epub 2021 Nov 18. Acc Chem Res. 2021. PMID: 34793124 Free PMC article.
After decades of extensive fundamental studies and clinical trials, lipid nanoparticles (LNPs) have demonstrated effective mRNA delivery such as the Moderna and Pfizer-BioNTech vaccines fighting against COVID-19. Moreover, researchers and clinicians have been …
After decades of extensive fundamental studies and clinical trials, lipid nanoparticles (LNPs) have demonstrated effective mRNA delivery suc …
Viral Vectors in Gene Therapy: Where Do We Stand in 2023?
Lundstrom K. Lundstrom K. Viruses. 2023 Mar 7;15(3):698. doi: 10.3390/v15030698. Viruses. 2023. PMID: 36992407 Free PMC article. Review.
In the context of cancer gene therapy, viral vectors expressing anti-tumor, toxic, suicide and immunostimulatory genes, such as cytokines and chemokines, have been applied. ...In a broader meaning, vaccine development against infectious diseases and various cancers has bee …
In the context of cancer gene therapy, viral vectors expressing anti-tumor, toxic, suicide and immunostimulatory genes, such as cytok …
Nanovaccine: an emerging strategy.
Das A, Ali N. Das A, et al. Expert Rev Vaccines. 2021 Oct;20(10):1273-1290. doi: 10.1080/14760584.2021.1984890. Epub 2021 Sep 29. Expert Rev Vaccines. 2021. PMID: 34550859 Review.
Subunit vaccines alone, however, fail to elicit sufficiently strong and long-lasting protective immunity against deadly pathogens. ...It provides a concise overview of current nanoparticle-based vaccines, their adjuvant potential and their cellular delivery mechanis …
Subunit vaccines alone, however, fail to elicit sufficiently strong and long-lasting protective immunity against deadly pathogens. .. …
Hydrogels for RNA delivery.
Zhong R, Talebian S, Mendes BB, Wallace G, Langer R, Conde J, Shi J. Zhong R, et al. Nat Mater. 2023 Jul;22(7):818-831. doi: 10.1038/s41563-023-01472-w. Epub 2023 Mar 20. Nat Mater. 2023. PMID: 36941391 Free PMC article. Review.
RNA-based therapeutics have shown tremendous promise in disease intervention at the genetic level, and some have been approved for clinical use, including the recent COVID-19 messenger RNA vaccines. The clinical success of RNA therapy is largely dependent on …
RNA-based therapeutics have shown tremendous promise in disease intervention at the genetic level, and some have been approved for clinical …
513 results