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Crocus Sativus L. (Saffron) in Alzheimer's Disease Treatment: Bioactive Effects on Cognitive Impairment.
D'Onofrio G, Nabavi SM, Sancarlo D, Greco A, Pieretti S. D'Onofrio G, et al. Curr Neuropharmacol. 2021;19(9):1606-1616. doi: 10.2174/1570159X19666210113144703. Curr Neuropharmacol. 2021. PMID: 33441068 Free PMC article. Review.
Crocus sativus L. (saffron) appears to own neuroprotective effects on cognitive impairment in patients with Alzheimer's disease (AD). ...As for the clinical studies, the selection criteria included: 1) patients aged 60, 2) AD diagnosis according
Crocus sativus L. (saffron) appears to own neuroprotective effects on cognitive impairment in patients with Alzheimer'
Antioxidant Properties of Crocus Sativus L. and Its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer's and Parkinson's Disease.
Hatziagapiou K, Kakouri E, Lambrou GI, Bethanis K, Tarantilis PA. Hatziagapiou K, et al. Curr Neuropharmacol. 2019;17(4):377-402. doi: 10.2174/1570159X16666180321095705. Curr Neuropharmacol. 2019. PMID: 29564976 Free PMC article. Review.
OBJECTIVE: The present study aims to address the protective role of Crocus Sativus L. in neurodegeneration with an emphasis in Parkinson's and Alzheimer's disease. ...RESULTS: Hence, the authors focused on the literature concerning the role of …
OBJECTIVE: The present study aims to address the protective role of Crocus Sativus L. in neurodegeneration with an emphasis in …
A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer's Disease.
Finley JW, Gao S. Finley JW, et al. J Agric Food Chem. 2017 Feb 8;65(5):1005-1020. doi: 10.1021/acs.jafc.6b04398. Epub 2017 Jan 31. J Agric Food Chem. 2017. PMID: 28098452 Review.
Alzheimer's disease (AD) is the most common form of dementia, in which the death of brain cells causes memory loss and cognitive decline. ...The biological properties of saffron, the dry stigma of the plant Crocus sativus L., and particularly it
Alzheimer's disease (AD) is the most common form of dementia, in which the death of brain cells causes memory loss and
Active constituents of saffron (Crocus sativus L.) and their prospects in treating neurodegenerative diseases (Review).
Yang W, Qiu X, Wu Q, Chang F, Zhou T, Zhou M, Pei J. Yang W, et al. Exp Ther Med. 2023 Apr 3;25(5):235. doi: 10.3892/etm.2023.11934. eCollection 2023 May. Exp Ther Med. 2023. PMID: 37114174 Free PMC article. Review.
Crocus sativus L. (saffron) is widely used as a traditional spice for flavoring, coloring and medicinal purposes. ...Thus, saffron has the potential to treat neurodegenerative diseases (NDs) associated with oxidative stress, inflammation and impaired mitochondrial f
Crocus sativus L. (saffron) is widely used as a traditional spice for flavoring, coloring and medicinal purposes. ...Thus, saf
Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway.
Wani A, Al Rihani SB, Sharma A, Weadick B, Govindarajan R, Khan SU, Sharma PR, Dogra A, Nandi U, Reddy CN, Bharate SS, Singh G, Bharate SB, Vishwakarma RA, Kaddoumi A, Kumar A. Wani A, et al. Autophagy. 2021 Nov;17(11):3813-3832. doi: 10.1080/15548627.2021.1872187. Epub 2021 Jan 19. Autophagy. 2021. PMID: 33404280 Free PMC article.
Alzheimer disease (AD) is usually accompanied by two prominent pathological features, cerebral accumulation of amyloid-beta (Abeta) plaques and presence of MAPT/tau neurofibrillary tangles. ...In this study, we have identified crocetin, a pharmacologically active co
Alzheimer disease (AD) is usually accompanied by two prominent pathological features, cerebral accumulation of amyloid-beta (A
The effects of Crocus sativus (saffron) and its constituents on nervous system: A review.
Khazdair MR, Boskabady MH, Hosseini M, Rezaee R, M Tsatsakis A. Khazdair MR, et al. Avicenna J Phytomed. 2015 Sep-Oct;5(5):376-91. Avicenna J Phytomed. 2015. PMID: 26468457 Free PMC article. Review.
Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. ...The anticonvulsant and anti-Alzheimer properties of saffron extract were shown in human and animal studies. ...
Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially …
Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases.
Ashktorab H, Soleimani A, Singh G, Amin A, Tabtabaei S, Latella G, Stein U, Akhondzadeh S, Solanki N, Gondré-Lewis MC, Habtezion A, Brim H. Ashktorab H, et al. Nutrients. 2019 Apr 26;11(5):943. doi: 10.3390/nu11050943. Nutrients. 2019. PMID: 31027364 Free PMC article.
Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases, Alzheimer's, rheumatoid arthritis as well as common malignancies of the colon, stomach, lung, breast, and skin. ...
Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases, Al
Neuropharmacological Aspects of Crocus sativus L.: A Review of Preclinical Studies and Ongoing Clinical Research.
Singh D. Singh D. CNS Neurol Disord Drug Targets. 2015;14(7):880-902. doi: 10.2174/1871527314666150303161817. CNS Neurol Disord Drug Targets. 2015. PMID: 25714974 Review.
Crocus sativus L. (Iridaceae) is an important member of the genus Crocus having high medicinal value. ...Many clinical studies proving beneficial effect of Crocus sativus in depressive disorders, Alzheimer's disease and so
Crocus sativus L. (Iridaceae) is an important member of the genus Crocus having high medicinal value. ...Many clinical
Crocus Sativus (Saffron): An Immunoregulatory Factor in the Autoimmune and Non-autoimmune Diseases.
Poursamimi J, Shariati-Sarabi Z, Tavakkol-Afshari J, Mohajeri SA, Mohammadi M. Poursamimi J, et al. Iran J Allergy Asthma Immunol. 2020 May 17;19(S1):27-42. doi: 10.18502/ijaai.v19i(s1.r1).2852. Iran J Allergy Asthma Immunol. 2020. PMID: 32534508 Free article. Review.
It has been reported that patients with arthritis, osteoarthritis, atherosclerosis, coronary artery disease, brain ischemia, diabetes, and inflammatory bowel disease (IBD) suffer from pro-inflammatory and oxidant related responses. ...Due to fact that several invest …
It has been reported that patients with arthritis, osteoarthritis, atherosclerosis, coronary artery disease, brain ischemia, diabetes …
Effects of saffron (Crocus sativus L.) on cognitive function. A systematic review of RCTs.
Avgerinos KI, Vrysis C, Chaitidis N, Kolotsiou K, Myserlis PG, Kapogiannis D. Avgerinos KI, et al. Neurol Sci. 2020 Oct;41(10):2747-2754. doi: 10.1007/s10072-020-04427-0. Epub 2020 May 23. Neurol Sci. 2020. PMID: 32445136 Free PMC article. Review.
INTRODUCTION: Improvement of cognitive function may be desirable for healthy individuals and clinically beneficial for those with cognitive impairment such as from Alzheimer's disease (AD) or mild cognitive impairment (MCI). The aim of this systematic review …
INTRODUCTION: Improvement of cognitive function may be desirable for healthy individuals and clinically beneficial for those with cognitive …
74 results