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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1982 1
1987 1
1989 2
1990 1
1991 1
1992 1
1993 1
1994 2
1995 1
1997 1
2001 1
2002 2
2003 2
2004 3
2005 2
2006 1
2008 1
2009 7
2010 2
2011 5
2012 1
2013 2
2014 1
2015 2
2016 1
2017 2
2020 2
2021 2
2023 1
2024 1

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53 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Cyclobenzaprine for the treatment of myofascial pain in adults.
Leite FM, Atallah AN, El Dib R, Grossmann E, Januzzi E, Andriolo RB, da Silva EM. Leite FM, et al. Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD006830. doi: 10.1002/14651858.CD006830.pub3. Cochrane Database Syst Rev. 2009. PMID: 19588406 Free PMC article. Review.
SELECTION CRITERIA: All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or secondary outcome. ...AUTHORS' CONCLUSIONS: There was insufficient evidence to support the use of cyclobenzaprine in the treatment of MP …
SELECTION CRITERIA: All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or sec …
Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review.
Chou R, Peterson K, Helfand M. Chou R, et al. J Pain Symptom Manage. 2004 Aug;28(2):140-75. doi: 10.1016/j.jpainsymman.2004.05.002. J Pain Symptom Manage. 2004. PMID: 15276195 Free article. Review.
Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. ...There is insufficient evidence to determine the relative efficacy or safety of cyclobenzaprine, carisoprodol, orphenadrine, tizanidine, metaxalone, met …
Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. ...There is insuffici …
Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double-Blind, Placebo-Controlled Trial.
Lederman S, Arnold LM, Vaughn B, Kelley M, Sullivan GM. Lederman S, et al. Arthritis Care Res (Hoboken). 2023 Nov;75(11):2359-2368. doi: 10.1002/acr.25142. Epub 2023 Jul 4. Arthritis Care Res (Hoboken). 2023. PMID: 37165930 Clinical Trial.
OBJECTIVE: To evaluate the efficacy and safety of TNX-102 SL, a once-nightly sublingual formulation of cyclobenzaprine, in reducing pain in patients with fibromyalgia (FM). ...
OBJECTIVE: To evaluate the efficacy and safety of TNX-102 SL, a once-nightly sublingual formulation of cyclobenzaprine, in reducing p …
Cyclobenzaprine and back pain: a meta-analysis.
Browning R, Jackson JL, O'Malley PG. Browning R, et al. Arch Intern Med. 2001 Jul 9;161(13):1613-20. doi: 10.1001/archinte.161.13.1613. Arch Intern Med. 2001. PMID: 11434793
BACKGROUND: Back pain is a common problem for which cyclobenzaprine hydrochloride is frequently prescribed. OBJECTIVE: To perform a systematic review of cyclobenzaprine's effectiveness in the treatment of back pain. ...CONCLUSIONS: Cyclobenzaprine is more eff …
BACKGROUND: Back pain is a common problem for which cyclobenzaprine hydrochloride is frequently prescribed. OBJECTIVE: To perform a s …
Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials.
Borenstein DG, Korn S. Borenstein DG, et al. Clin Ther. 2003 Apr;25(4):1056-73. doi: 10.1016/s0149-2918(03)80067-x. Clin Ther. 2003. PMID: 12809957 Clinical Trial.
Although physicians frequently prescribe an analgesic or NSAID in addition to cyclobenzaprine, these studies were not designed to assess whether adding cyclobenzaprine provides a benefit over that of an analgesic. ...On day 7, significantly more patients receiving …
Although physicians frequently prescribe an analgesic or NSAID in addition to cyclobenzaprine, these studies were not designed to ass …
A randomized trial of cyclobenzaprine for the treatment of fibromyalgia.
Quimby LG, Gratwick GM, Whitney CD, Block SR. Quimby LG, et al. J Rheumatol Suppl. 1989 Nov;19:140-3. J Rheumatol Suppl. 1989. PMID: 2481741 Clinical Trial.
We attempted a randomized, double blind trial of placebo vs cyclobenzaprine (Flexeril) in 40 female patients with fibromyalgia from a private rheumatology practice in Maine. ...How much this awareness contributed to the perceived effectiveness of cyclobenzaprine is …
We attempted a randomized, double blind trial of placebo vs cyclobenzaprine (Flexeril) in 40 female patients with fibromyalgia from a …
Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency.
Winchell GA, King JD, Chavez-Eng CM, Constanzer ML, Korn SH. Winchell GA, et al. J Clin Pharmacol. 2002 Jan;42(1):61-9. doi: 10.1177/0091270002042001007. J Clin Pharmacol. 2002. PMID: 11808825 Clinical Trial.
Cyclobenzaprine plasma clearance was 689 ml/min, and the bioavailability of a 5 mg oral dose was 0.55. Following oral doses of 2.5 to 10 mg tid in healthy young subjects, cyclobenzaprine pharmacokinetics were linear, and plasma concentrations generally increased pro …
Cyclobenzaprine plasma clearance was 689 ml/min, and the bioavailability of a 5 mg oral dose was 0.55. Following oral doses of 2.5 to …
Cyclobenzaprine with ibuprofen versus ibuprofen alone in acute myofascial strain: a randomized, double-blind clinical trial.
Turturro MA, Frater CR, D'Amico FJ. Turturro MA, et al. Ann Emerg Med. 2003 Jun;41(6):818-26. doi: 10.1067/mem.2003.188. Ann Emerg Med. 2003. PMID: 12764337 Clinical Trial.
STUDY OBJECTIVE: We evaluate the analgesic and side effects of adding cyclobenzaprine to ibuprofen in emergency department patients with acute myofascial strain. ...In addition, 51 patients received a single dose of 10 mg of cyclobenzaprine and a vial of 6 capsules …
STUDY OBJECTIVE: We evaluate the analgesic and side effects of adding cyclobenzaprine to ibuprofen in emergency department patients w …
Cyclobenzaprine and naproxen versus naproxen alone in the treatment of acute low back pain and muscle spasm.
Borenstein DG, Lacks S, Wiesel SW. Borenstein DG, et al. Clin Ther. 1990 Mar-Apr;12(2):125-31. Clin Ther. 1990. PMID: 2141299 Clinical Trial.
Cyclobenzaprine was added to the naproxen regimen as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful, musculoskeletal conditions. ...Combination therapy was associated with more side effects, due primarily to drowsiness fro …
Cyclobenzaprine was added to the naproxen regimen as an adjunct to rest and physical therapy for relief of muscle spasm associated wi …
Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets.
Brioschi TM, Schramm SG, Kano EK, Koono EE, Ching TH, Serra CH, Porta V. Brioschi TM, et al. Biomed Res Int. 2013;2013:281392. doi: 10.1155/2013/281392. Epub 2013 Sep 16. Biomed Res Int. 2013. PMID: 24151591 Free PMC article. Clinical Trial.
The purpose of this study was to investigate cyclobenzaprine pharmacokinetics and to evaluate bioequivalence between two different tablet formulations containing the drug. ...Cyclobenzaprine plasma profiles for the reference and test products were similar, as well a …
The purpose of this study was to investigate cyclobenzaprine pharmacokinetics and to evaluate bioequivalence between two different ta …
53 results

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