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Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes.
Schröder SP, de Boer C, McGregor NGS, Rowland RJ, Moroz O, Blagova E, Reijngoud J, Arentshorst M, Osborn D, Morant MD, Abbate E, Stringer MA, Krogh KBRM, Raich L, Rovira C, Berrin JG, van Wezel GP, Ram AFJ, Florea BI, van der Marel GA, Codée JDC, Wilson KS, Wu L, Davies GJ, Overkleeft HS. Schröder SP, et al. Among authors: de boer c. ACS Cent Sci. 2019 Jun 26;5(6):1067-1078. doi: 10.1021/acscentsci.9b00221. Epub 2019 May 24. ACS Cent Sci. 2019. PMID: 31263766 Free PMC article.
An overview of activity-based probes for glycosidases.
Wu L, Armstrong Z, Schröder SP, de Boer C, Artola M, Aerts JM, Overkleeft HS, Davies GJ. Wu L, et al. Among authors: de boer c. Curr Opin Chem Biol. 2019 Dec;53:25-36. doi: 10.1016/j.cbpa.2019.05.030. Epub 2019 Aug 13. Curr Opin Chem Biol. 2019. PMID: 31419756 Review.
Direct Stereoselective Aziridination of Cyclohexenols with 3-Amino-2-(trifluoromethyl)quinazolin-4(3H)-one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors.
Artola M, Wouters S, Schröder SP, de Boer C, Chen Y, Petracca R, van den Nieuwendijk AMCH, Aerts JMFG, van der Marel GA, Codée JDC, Overkleeft HS. Artola M, et al. Among authors: de boer c. European J Org Chem. 2019 Feb 14;2019(6):1397-1404. doi: 10.1002/ejoc.201801703. Epub 2019 Jan 11. European J Org Chem. 2019. PMID: 31787842 Free PMC article.
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, van der Stelt M, van der Marel GM, Codée JDC, Aerts JMFG, Wu L, Overkleeft HS, Davies GJ. Armstrong Z, et al. Among authors: de boer c. J Am Chem Soc. 2020 Jul 29;142(30):13021-13029. doi: 10.1021/jacs.0c03880. Epub 2020 Jul 16. J Am Chem Soc. 2020. PMID: 32605368
Activity-Based Protein Profiling of Retaining α-Amylases in Complex Biological Samples.
Chen Y, Armstrong Z, Artola M, Florea BI, Kuo CL, de Boer C, Rasmussen MS, Abou Hachem M, van der Marel GA, Codée JDC, Aerts JMFG, Davies GJ, Overkleeft HS. Chen Y, et al. Among authors: de boer c. J Am Chem Soc. 2021 Feb 10;143(5):2423-2432. doi: 10.1021/jacs.0c13059. Epub 2021 Jan 26. J Am Chem Soc. 2021. PMID: 33497208 Free PMC article.
Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases.
de Boer C, McGregor NGS, Peterse E, Schröder SP, Florea BI, Jiang J, Reijngoud J, Ram AFJ, van Wezel GP, van der Marel GA, Codée JDC, Overkleeft HS, Davies GJ. de Boer C, et al. RSC Chem Biol. 2020 Jul 28;1(3):148-155. doi: 10.1039/d0cb00045k. eCollection 2020 Aug 1. RSC Chem Biol. 2020. PMID: 34458755 Free PMC article.
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
de Boer C, Armstrong Z, Lit VAJ, Barash U, Ruijgrok G, Boyango I, Weitzenberg MM, Schröder SP, Sarris AJC, Meeuwenoord NJ, Bule P, Kayal Y, Ilan N, Codée JDC, Vlodavsky I, Overkleeft HS, Davies GJ, Wu L. de Boer C, et al. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203167119. doi: 10.1073/pnas.2203167119. Epub 2022 Jul 26. Proc Natl Acad Sci U S A. 2022. PMID: 35881786 Free PMC article.
234 results