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PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
Sladky VC, Knapp K, Szabo TG, Braun VZ, Bongiovanni L, van den Bos H, Spierings DC, Westendorp B, Curinha A, Stojakovic T, Scharnagl H, Timelthaler G, Tsuchia K, Pinter M, Semmler G, Foijer F, de Bruin A, Reiberger T, Rohr-Udilova N, Villunger A. Sladky VC, et al. Among authors: de bruin a. EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23. EMBO Rep. 2020. PMID: 33225610 Free PMC article.
E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Sladky VC, Knapp K, Soratroi C, Heppke J, Eichin F, Rocamora-Reverte L, Szabo TG, Bongiovanni L, Westendorp B, Moreno E, van Liere EA, Bakker B, Spierings DCJ, Wardenaar R, Pereyra D, Starlinger P, Schultze S, Trauner M, Stojakovic T, Scharnagl H, Fava LL, Foijer F, de Bruin A, Villunger A. Sladky VC, et al. Among authors: de bruin a. Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23. Dev Cell. 2020. PMID: 31983631 Free article.
Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.
Aziz K, Limzerwala JF, Sturmlechner I, Hurley E, Zhang C, Jeganathan KB, Nelson G, Bronk S, Fierro Velasco RO, van Deursen EJ, O'Brien DR, Kocher JA, Youssef SA, van Ree JH, de Bruin A, van den Bos H, Spierings DCJ, Foijer F, van de Sluis B, Roberts LR, Gores GJ, Li H, van Deursen JM. Aziz K, et al. Among authors: de bruin a. Gastroenterology. 2019 Jul;157(1):210-226.e12. doi: 10.1053/j.gastro.2019.03.016. Epub 2019 Mar 13. Gastroenterology. 2019. PMID: 30878468 Free PMC article.
E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.
Moreno E, Toussaint MJM, van Essen SC, Bongiovanni L, van Liere EA, Koster MH, Yuan R, van Deursen JM, Westendorp B, de Bruin A. Moreno E, et al. Among authors: de bruin a. Hepatology. 2021 Jan;73(1):303-317. doi: 10.1002/hep.31259. Hepatology. 2021. PMID: 32259305 Free PMC article.
Inhibition of polyploidization in Pten-deficient livers reduces steatosis.
Moreno E, Matondo AB, Bongiovanni L, van de Lest CHA, Molenaar MR, Toussaint MJM, van Essen SC, Houweling M, Helms JB, Westendorp B, de Bruin A. Moreno E, et al. Among authors: de bruin a. Liver Int. 2022 Nov;42(11):2442-2452. doi: 10.1111/liv.15384. Epub 2022 Sep 2. Liver Int. 2022. PMID: 35924448 Free PMC article.
CDC6: A novel canine tumour biomarker detected in circulating extracellular vesicles.
Andriessen A, Bongiovanni L, Driedonks TAP, van Liere E, Seijger A, Hegeman CV, van Nimwegen SA, Galac S, Westendorp B, Nolte-'t Hoen ENM, de Bruin A. Andriessen A, et al. Among authors: de bruin a. Vet Comp Oncol. 2022 Jun;20(2):381-392. doi: 10.1111/vco.12781. Epub 2021 Nov 17. Vet Comp Oncol. 2022. PMID: 34743398 Free PMC article.
381 results