de Winther MPJ - Search Results

1

The Link between Hematopoiesis and Atherosclerosis.

de Winther MPJ, Lutgens E. de Winther MPJ, et al. N Engl J Med. 2019 May 9;380(19):1869-1871. doi: 10.1056/NEJMcibr1901397. N Engl J Med. 2019. PMID: 31067380 No abstract available.

2

Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis.

Smook ML, Heeringa P, Damoiseaux JG, Daemen MJ, de Winther MP, Gijbels MJ, Beckers L, Lutgens E, Tervaert JW. Smook ML, et al. Atherosclerosis. 2005 Dec;183(2):275-82. doi: 10.1016/j.atherosclerosis.2005.03.051. Epub 2005 Jul 5. Atherosclerosis. 2005. PMID: 16002076

3

Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation.

Lutgens E, Lutgens SP, Faber BC, Heeneman S, Gijbels MM, de Winther MP, Frederik P, van der Made I, Daugherty A, Sijbers AM, Fisher A, Long CJ, Saftig P, Black D, Daemen MJ, Cleutjens KB. Lutgens E, et al. Circulation. 2006 Jan 3;113(1):98-107. doi: 10.1161/CIRCULATIONAHA.105.561449. Epub 2005 Dec 19. Circulation. 2006. PMID: 16365196

4

Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic.

Lutgens SP, Kisters N, Lutgens E, van Haaften RI, Evelo CT, de Winther MP, Saftig P, Daemen MJ, Heeneman S, Cleutjens KB. Lutgens SP, et al. J Pathol. 2006 Nov;210(3):334-43. doi: 10.1002/path.2054. J Pathol. 2006. PMID: 16972305

5

Disruption of hedgehog signalling in ApoE - /- mice reduces plasma lipid levels, but increases atherosclerosis due to enhanced lipid uptake by macrophages.

Beckers L, Heeneman S, Wang L, Burkly LC, Rousch MM, Davidson NO, Gijbels MJ, de Winther MP, Daemen MJ, Lutgens E. Beckers L, et al. J Pathol. 2007 Aug;212(4):420-8. doi: 10.1002/path.2193. J Pathol. 2007. PMID: 17573667

6

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice.

Xanthoulea S, Thelen M, Pöttgens C, Gijbels MJ, Lutgens E, de Winther MP. Xanthoulea S, et al. PLoS One. 2009 Jul 7;4(7):e6113. doi: 10.1371/journal.pone.0006113. PLoS One. 2009. PMID: 19582157 Free PMC article.

7

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.

Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Lutgens E, et al. J Exp Med. 2010 Feb 15;207(2):391-404. doi: 10.1084/jem.20091293. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100871 Free PMC article.

8

Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions.

Goossens P, Gijbels MJ, Zernecke A, Eijgelaar W, Vergouwe MN, van der Made I, Vanderlocht J, Beckers L, Buurman WA, Daemen MJ, Kalinke U, Weber C, Lutgens E, de Winther MP. Goossens P, et al. Cell Metab. 2010 Aug 4;12(2):142-53. doi: 10.1016/j.cmet.2010.06.008. Cell Metab. 2010. PMID: 20674859 Free article.

9

Distribution of macrophage polarization markers in human atherosclerosis.

Stöger JL, Gijbels MJ, van der Velden S, Manca M, van der Loos CM, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Stöger JL, et al. Atherosclerosis. 2012 Dec;225(2):461-8. doi: 10.1016/j.atherosclerosis.2012.09.013. Epub 2012 Sep 26. Atherosclerosis. 2012. PMID: 23078881 Free article.

10

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, de Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Heymans S, et al. Circulation. 2013 Sep 24;128(13):1420-32. doi: 10.1161/CIRCULATIONAHA.112.001357. Epub 2013 Aug 16. Circulation. 2013. PMID: 23956210

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