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T cells expressing the activating NK-cell receptors KIR2DS4, NKG2C and NKG2D are elevated in paroxysmal nocturnal hemoglobinuria and cytotoxic toward hematopoietic progenitor cell lines.
van Bijnen ST, Withaar M, Preijers F, van der Meer A, de Witte T, Muus P, Dolstra H. van Bijnen ST, et al. Among authors: de witte t. Exp Hematol. 2011 Jul;39(7):751-62.e1-3. doi: 10.1016/j.exphem.2011.04.003. Epub 2011 Apr 21. Exp Hematol. 2011. PMID: 21554925 Free article.
Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation.
Hobo W, Broen K, van der Velden WJ, Greupink-Draaisma A, Adisty N, Wouters Y, Kester M, Fredrix H, Jansen JH, van der Reijden B, Falkenburg JH, de Witte T, Preijers F, Schattenberg T, Feuth T, Blijlevens NM, Schaap N, Dolstra H. Hobo W, et al. Among authors: de witte t. Biol Blood Marrow Transplant. 2013 Feb;19(2):274-82. doi: 10.1016/j.bbmt.2012.09.008. Epub 2012 Sep 27. Biol Blood Marrow Transplant. 2013. PMID: 23022467 Free PMC article.
Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients.
Hobo W, Strobbe L, Maas F, Fredrix H, Greupink-Draaisma A, Esendam B, de Witte T, Preijers F, Levenga H, van Rees B, Raymakers R, Schaap N, Dolstra H. Hobo W, et al. Among authors: de witte t. Cancer Immunol Immunother. 2013 Aug;62(8):1381-92. doi: 10.1007/s00262-013-1438-2. Epub 2013 Jun 2. Cancer Immunol Immunother. 2013. PMID: 23728352 Free PMC article. Clinical Trial.
Counterflow centrifugation allows addition of appropriate numbers of T cells to allogeneic marrow and blood stem cell grafts to prevent severe GVHD without substantial loss of mature and immature progenitor cells.
Preijers FW, van Hennik PB, Schattenberg A, Ruijs P, Ploemacher RE, de Witte T. Preijers FW, et al. Among authors: de witte t. Bone Marrow Transplant. 1999 May;23(10):1061-70. doi: 10.1038/sj.bmt.1701775. Bone Marrow Transplant. 1999. PMID: 10373074
Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma.
Levenga H, Schaap N, Maas F, Esendam B, Fredrix H, Greupink-Draaisma A, de Witte T, Dolstra H, Raymakers R. Levenga H, et al. Among authors: de witte t. Biol Blood Marrow Transplant. 2010 Mar;16(3):320-32. doi: 10.1016/j.bbmt.2009.10.006. Epub 2009 Oct 14. Biol Blood Marrow Transplant. 2010. PMID: 19835972 Free article. Clinical Trial.
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