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Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages.
Ramírez CM, Torrecilla-Parra M, Pardo-Marqués V, de-Frutos MF, Pérez-García A, Tabraue C, de la Rosa JV, Martín-Rodriguez P, Díaz-Sarmiento M, Nuñez U, Orizaola MC, Través PG, Camps M, Boscá L, Castrillo A. Ramírez CM, et al. Among authors: de la rosa jv. Front Endocrinol (Lausanne). 2021 May 27;12:635923. doi: 10.3389/fendo.2021.635923. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34122329 Free PMC article.
Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages.
González de la Aleja A, Herrero C, Torres-Torresano M, de la Rosa JV, Alonso B, Capa-Sardón E, Muller IB, Jansen G, Puig-Kröger A, Vega MA, Castrillo A, Corbí ÁL. González de la Aleja A, et al. Among authors: de la rosa jv. Front Immunol. 2022 Feb 24;13:835478. doi: 10.3389/fimmu.2022.835478. eCollection 2022. Front Immunol. 2022. PMID: 35280993 Free PMC article.
The nuclear receptor LXRα controls the functional specialization of splenic macrophages.
A-Gonzalez N, Guillen JA, Gallardo G, Diaz M, de la Rosa JV, Hernandez IH, Casanova-Acebes M, Lopez F, Tabraue C, Beceiro S, Hong C, Lara PC, Andujar M, Arai S, Miyazaki T, Li S, Corbi AL, Tontonoz P, Hidalgo A, Castrillo A. A-Gonzalez N, et al. Among authors: de la rosa jv. Nat Immunol. 2013 Aug;14(8):831-9. doi: 10.1038/ni.2622. Epub 2013 Jun 16. Nat Immunol. 2013. PMID: 23770640 Free PMC article.
Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment.
Carbó JM, León TE, Font-Díaz J, De la Rosa JV, Castrillo A, Picard FR, Staudenraus D, Huber M, Cedó L, Escolà-Gil JC, Campos L, Bakiri L, Wagner EF, Caelles C, Stratmann T, Van Ginderachter JA, Valledor AF. Carbó JM, et al. Among authors: de la rosa jv. Cancer Res. 2021 Feb 15;81(4):968-985. doi: 10.1158/0008-5472.CAN-19-3360. Epub 2020 Dec 23. Cancer Res. 2021. PMID: 33361391 Free article.
20 results